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Results: 1 to 20 of 109

1.

Application of physiologically-based toxicokinetic modelling in oral-to-dermal extrapolation of threshold doses of cosmetic ingredients.

Gajewska M, Worth A, Urani C, Briesen H, Schramm KW.

Toxicol Lett. 2014 Jun 16;227(3):189-202. doi: 10.1016/j.toxlet.2014.03.013. Epub 2014 Apr 13.

PMID:
24731971
[PubMed - indexed for MEDLINE]
Free Article
2.

Physiologically based toxicokinetic modelling as a tool to assess target organ toxicity in route-to-route extrapolation--the case of coumarin.

Mielke H, Abraham K, Götz M, Vieth B, Lampen A, Luch A, Gundert-Remy U.

Toxicol Lett. 2011 Apr 25;202(2):100-10. doi: 10.1016/j.toxlet.2011.01.022. Epub 2011 Feb 1.

PMID:
21291965
[PubMed - indexed for MEDLINE]
3.

Simulation of urinary excretion of 1-hydroxypyrene in various scenarios of exposure to polycyclic aromatic hydrocarbons with a generic, cross-chemical predictive PBTK-model.

Jongeneelen F, ten Berge W.

Int Arch Occup Environ Health. 2012 Aug;85(6):689-702. doi: 10.1007/s00420-011-0713-9. Epub 2011 Oct 29.

PMID:
22038087
[PubMed - indexed for MEDLINE]
4.
6.

The acute effects of daily nicotine intake on heart rate - A toxicokinetic and toxicodynamic modelling study.

Gajewska M, Worth A, Urani C, Briesen H, Schramm KW.

Regul Toxicol Pharmacol. 2014 Oct;70(1):312-24. doi: 10.1016/j.yrtph.2014.07.015. Epub 2014 Jul 24.

PMID:
25066669
[PubMed - in process]
Free Article
9.

The contribution of dermal exposure to the internal exposure of bisphenol A in man.

Mielke H, Partosch F, Gundert-Remy U.

Toxicol Lett. 2011 Jul 28;204(2-3):190-8. doi: 10.1016/j.toxlet.2011.04.032. Epub 2011 May 5.

PMID:
21571050
[PubMed - indexed for MEDLINE]
10.

Hydroquinone PBPK model refinement and application to dermal exposure.

Poet TS, Carlton BD, Deyo JA, Hinderliter PM.

Food Chem Toxicol. 2010 Nov;48(11):3085-92. doi: 10.1016/j.fct.2010.08.002. Epub 2010 Aug 6.

PMID:
20692312
[PubMed - indexed for MEDLINE]
11.

Comparison of PBTK model and biomarker based estimates of the internal dosimetry of acrylamide.

DeWoskin RS, Sweeney LM, Teeguarden JG, Sams R 2nd, Vandenberg J.

Food Chem Toxicol. 2013 Aug;58:506-21. doi: 10.1016/j.fct.2013.05.008. Epub 2013 May 21.

PMID:
23707562
[PubMed - indexed for MEDLINE]
13.
14.

Prediction of concentration-time profile and its inter-individual variability following the dermal drug absorption.

Polak S, Ghobadi C, Mishra H, Ahamadi M, Patel N, Jamei M, Rostami-Hodjegan A.

J Pharm Sci. 2012 Jul;101(7):2584-95. doi: 10.1002/jps.23155. Epub 2012 Apr 19.

PMID:
22517028
[PubMed - indexed for MEDLINE]
16.

Development of physiologically based toxicokinetic models for improving the human indoor exposure assessment to water contaminants: trichloroethylene and trihalomethanes.

Haddad S, Tardif GC, Tardif R.

J Toxicol Environ Health A. 2006 Dec;69(23):2095-136.

PMID:
17060096
[PubMed - indexed for MEDLINE]
17.

Physiologically based toxicokinetic modelling as a tool to support risk assessment: three case studies.

Mielke H, Gundert-Remy U.

J Toxicol. 2012;2012:359471. doi: 10.1155/2012/359471. Epub 2012 May 9.

PMID:
22649449
[PubMed]
Free PMC Article
18.

PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthalene.

Kim D, Andersen ME, Chao YC, Egeghy PP, Rappaport SM, Nylander-French LA.

Environ Health Perspect. 2007 Jun;115(6):894-901. Epub 2007 Feb 14.

PMID:
17589597
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The role of hair follicles in the percutaneous absorption of caffeine.

Otberg N, Patzelt A, Rasulev U, Hagemeister T, Linscheid M, Sinkgraven R, Sterry W, Lademann J.

Br J Clin Pharmacol. 2008 Apr;65(4):488-92. Epub 2007 Dec 7.

PMID:
18070215
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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