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Results: 1 to 20 of 102

Similar articles for PubMed (Select 24726842)

1.

VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats.

Godbole AM, Ramalingam S, Ramamurthy VP, Khandelwal A, Bruno RD, Upreti VV, Gediya LK, Purushottamachar P, Mbatia HW, Addya S, Ambulos N, Njar VC.

Eur J Pharmacol. 2014 Jul 5;734:98-104. doi: 10.1016/j.ejphar.2014.04.004. Epub 2014 Apr 12.

PMID:
24726842
2.
3.

Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth.

Patel JB, Mehta J, Belosay A, Sabnis G, Khandelwal A, Brodie AM, Soprano DR, Njar VC.

Br J Cancer. 2007 Apr 23;96(8):1204-15. Epub 2007 Mar 27.

4.

Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenografts.

Godbole AM, Purushottamachar P, Martin MS, Daskalakis C, Njar VC.

Mol Cancer Ther. 2012 Apr;11(4):898-908. doi: 10.1158/1535-7163.MCT-11-0860. Epub 2012 Feb 14.

5.

Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1.

Godbole AM, Purushottamachar P, Martin MS, Njar VC.

Cancer Chemother Pharmacol. 2012 Aug;70(2):339-44. doi: 10.1007/s00280-012-1877-z. Epub 2012 May 13.

6.

17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response.

Bruno RD, Gover TD, Burger AM, Brodie AM, Njar VC.

Mol Cancer Ther. 2008 Sep;7(9):2828-36. doi: 10.1158/1535-7163.MCT-08-0336.

7.

Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus.

Goss PE, Qi S, Hu H, Gediya LK, Purushottamachar P, Godbole AM, Njar VC.

Breast Cancer Res Treat. 2012 May;133(1):137-44. doi: 10.1007/s10549-011-1724-7. Epub 2011 Aug 14.

8.

Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.

Patel JB, Khandelwal A, Chopra P, Handratta VD, Njar VC.

Cancer Chemother Pharmacol. 2007 Nov;60(6):899-905. Epub 2007 Mar 8.

PMID:
17345084
9.

Combined treatment with SAHA, bortezomib, and clarithromycin for concomitant targeting of aggresome formation and intracellular proteolytic pathways enhances ER stress-mediated cell death in breast cancer cells.

Komatsu S, Moriya S, Che XF, Yokoyama T, Kohno N, Miyazawa K.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):41-7. doi: 10.1016/j.bbrc.2013.06.032. Epub 2013 Jun 18.

PMID:
23792097
10.

MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours.

Khandelwal A, Gediya L, Njar V.

Br J Cancer. 2008 Apr 8;98(7):1234-43. doi: 10.1038/sj.bjc.6604295. Epub 2008 Mar 18.

11.

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo.

Chiu HW, Yeh YL, Wang YC, Huang WJ, Chen YA, Chiou YS, Ho SY, Lin P, Wang YJ.

PLoS One. 2013 Oct 10;8(10):e76340. doi: 10.1371/journal.pone.0076340. eCollection 2013.

12.

Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors.

Thomas S, Sharma N, Golden EB, Cho H, Agarwal P, Gaffney KJ, Petasis NA, Chen TC, Hofman FM, Louie SG, Schönthal AH.

Cancer Lett. 2012 Dec 1;325(1):63-71. doi: 10.1016/j.canlet.2012.05.030. Epub 2012 Jun 1.

PMID:
22664238
13.

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.

Periyasamy-Thandavan S, Jackson WH, Samaddar JS, Erickson B, Barrett JR, Raney L, Gopal E, Ganapathy V, Hill WD, Bhalla KN, Schoenlein PV.

Autophagy. 2010 Jan;6(1):19-35.

14.

Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress.

Shi JM, Bai LL, Zhang DM, Yiu A, Yin ZQ, Han WL, Liu JS, Li Y, Fu DY, Ye WC.

Biochem Pharmacol. 2013 Apr 1;85(7):913-26. doi: 10.1016/j.bcp.2013.01.009. Epub 2013 Jan 21.

PMID:
23348250
15.

Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.

Brüning A, Friese K, Burges A, Mylonas I.

Breast Cancer Res. 2010;12(4):R45. doi: 10.1186/bcr2602. Epub 2010 Jul 1.

16.

Aromatase and breast cancer.

Brodie A, Sabnis G, Jelovac D.

J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):97-102.

17.

Apoptosis and autophagy in breast cancer cells following exemestane treatment.

Amaral C, Borges M, Melo S, da Silva ET, Correia-da-Silva G, Teixeira N.

PLoS One. 2012;7(8):e42398. doi: 10.1371/journal.pone.0042398. Epub 2012 Aug 13.

18.

Inhibition of autophagy enhances the cytotoxic effect of PA-MSHA in breast cancer.

Xu WH, Liu ZB, Hou YF, Hong Q, Hu DL, Shao ZM.

BMC Cancer. 2014 Apr 21;14:273. doi: 10.1186/1471-2407-14-273.

19.

Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells.

Chiu HW, Tseng YC, Hsu YH, Lin YF, Foo NP, Guo HR, Wang YJ.

Cancer Lett. 2015 Jan 28;356(2 Pt B):762-72. doi: 10.1016/j.canlet.2014.10.025. Epub 2014 Oct 27.

PMID:
25449439
20.

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells.

Cheng X, Liu H, Jiang CC, Fang L, Chen C, Zhang XD, Jiang ZW.

Int J Mol Med. 2014 Sep;34(3):772-81. doi: 10.3892/ijmm.2014.1822. Epub 2014 Jun 25.

PMID:
24970676
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