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Results: 1 to 20 of 107

Similar articles for PubMed (Select 24726726)

1.

Molecular insights into NF2/Merlin tumor suppressor function.

Cooper J, Giancotti FG.

FEBS Lett. 2014 Aug 19;588(16):2743-52. doi: 10.1016/j.febslet.2014.04.001. Epub 2014 Apr 12. Review.

PMID:
24726726
2.

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG.

Cell. 2010 Feb 19;140(4):477-90. doi: 10.1016/j.cell.2010.01.029.

3.

Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression.

Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG.

Sci Signal. 2011 Aug 23;4(188):pt6. doi: 10.1126/scisignal.2002314.

PMID:
21878678
4.

Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4 (DCAF1).

Li W, Giancotti FG.

Cell Cycle. 2010 Nov 15;9(22):4433-6. Epub 2010 Nov 15.

5.

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.

Li W, Cooper J, Karajannis MA, Giancotti FG.

EMBO Rep. 2012 Mar;13(3):204-15. Review.

6.
7.

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway.

Li Y, Zhou H, Li F, Chan SW, Lin Z, Wei Z, Yang Z, Guo F, Lim CJ, Xing W, Shen Y, Hong W, Long J, Zhang M.

Cell Res. 2015 Jul;25(7):801-17. doi: 10.1038/cr.2015.69. Epub 2015 Jun 5.

PMID:
26045165
8.

Merlin, a multi-suppressor from cell membrane to the nucleus.

Zhou L, Hanemann CO.

FEBS Lett. 2012 May 21;586(10):1403-8. doi: 10.1016/j.febslet.2012.03.016. Epub 2012 Mar 21. Review.

9.

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus.

Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, Karajannis MA, Giancotti FG.

Cancer Cell. 2014 Jul 14;26(1):48-60. doi: 10.1016/j.ccr.2014.05.001.

PMID:
25026211
10.

Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.

Laulajainen M, Muranen T, Nyman TA, Carpén O, Grönholm M.

Neoplasia. 2011 Jul;13(7):643-52.

11.

Shedding light on Merlin's wizardry.

Okada T, You L, Giancotti FG.

Trends Cell Biol. 2007 May;17(5):222-9. Epub 2007 Apr 17. Review. Erratum in: Trends Cell Biol. 2008 Jan;18(1):11.

PMID:
17442573
12.

Merlin, the NF2 gene product.

Pećina-Šlaus N.

Pathol Oncol Res. 2013 Jul;19(3):365-73. doi: 10.1007/s12253-013-9644-y. Epub 2013 May 12. Review.

PMID:
23666797
13.

Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.

Li Y, Wei Z, Zhang J, Yang Z, Zhang M.

J Biol Chem. 2014 May 23;289(21):14674-81. doi: 10.1074/jbc.M114.551184. Epub 2014 Apr 4.

14.

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.

Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL.

Cancer Cell. 2011 Apr 12;19(4):527-40. doi: 10.1016/j.ccr.2011.02.017.

15.

Merlin sumoylation is required for its tumor suppressor activity.

Qi Q, Liu X, Brat DJ, Ye K.

Oncogene. 2014 Oct 9;33(41):4893-903. doi: 10.1038/onc.2013.438. Epub 2013 Oct 28.

PMID:
24166499
16.

NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.

James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V.

Mol Cell Biol. 2009 Aug;29(15):4250-61. doi: 10.1128/MCB.01581-08. Epub 2009 May 18.

18.

The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.

Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A.

Neoplasia. 2008 Nov;10(11):1204-12.

19.

Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein.

Lee H, Kim D, Dan HC, Wu EL, Gritsko TM, Cao C, Nicosia SV, Golemis EA, Liu W, Coppola D, Brem SS, Testa JR, Cheng JQ.

Mol Cell Biol. 2007 Mar;27(6):2103-19. Epub 2007 Jan 8.

20.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

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