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Results: 1 to 20 of 100

1.

Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection.

Perisé-Barrios AJ, Jiménez JL, Domínguez-Soto A, de la Mata FJ, Corbí AL, Gomez R, Muñoz-Fernandez MÁ.

J Control Release. 2014 Jun 28;184:51-7. doi: 10.1016/j.jconrel.2014.03.048. Epub 2014 Apr 8.

PMID:
24721235
[PubMed - indexed for MEDLINE]
2.

Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes.

Weber N, Ortega P, Clemente MI, Shcharbin D, Bryszewska M, de la Mata FJ, Gómez R, Muñoz-Fernández MA.

J Control Release. 2008 Nov 24;132(1):55-64. doi: 10.1016/j.jconrel.2008.07.035. Epub 2008 Aug 5.

PMID:
18727943
[PubMed - indexed for MEDLINE]
3.

Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile.

Chonco L, Pion M, Vacas E, Rasines B, Maly M, Serramía MJ, López-Fernández L, De la Mata J, Alvarez S, Gómez R, Muñoz-Fernández MA.

J Control Release. 2012 Aug 10;161(3):949-58. doi: 10.1016/j.jconrel.2012.04.050. Epub 2012 May 28.

PMID:
22652549
[PubMed - indexed for MEDLINE]
4.

Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16.

Gras R, Almonacid L, Ortega P, Serramia MJ, Gomez R, de la Mata FJ, Lopez-Fernandez LA, Muñoz-Fernandez MA.

Pharm Res. 2009 Mar;26(3):577-86. doi: 10.1007/s11095-008-9776-z. Epub 2008 Nov 25. Erratum in: Pharm Res. 2011 Mar;28(3):683-7.

PMID:
19034630
[PubMed - indexed for MEDLINE]
5.

Gene therapy in HIV-infected cells to decrease viral impact by using an alternative delivery method.

Gonzalo T, Clemente MI, Chonco L, Weber ND, Díaz L, Serramía MJ, Gras R, Ortega P, de la Mata FJ, Gómez R, Lopez-Fernández LA, Muñoz-Fernández MA, Jiménez JL.

ChemMedChem. 2010 Jun 7;5(6):921-9. doi: 10.1002/cmdc.201000029.

PMID:
20414916
[PubMed - indexed for MEDLINE]
6.

Carbosilane dendrimer 2G-NN16 represses Tc17 differentiation in primary T CD8+ lymphocytes.

Gras R, García MI, Gómez R, de la Mata FJ, Muñoz-Fernández MA, López-Fernández LA.

Mol Pharm. 2012 Jan 1;9(1):102-10. doi: 10.1021/mp200305u. Epub 2011 Nov 16.

PMID:
22023154
[PubMed - indexed for MEDLINE]
7.

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.

Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ.

Mol Ther. 2011 Dec;19(12):2228-38. doi: 10.1038/mt.2011.207. Epub 2011 Sep 27.

PMID:
21952167
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Validation of a generation 4 phosphorus-containing polycationic dendrimer for gene delivery against HIV-1.

Briz V, Serramía MJ, Madrid R, Hameau A, Caminade AM, Majoral JP, Muñoz-Fernández MA.

Curr Med Chem. 2012;19(29):5044-51.

PMID:
22963636
[PubMed - indexed for MEDLINE]
9.

Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress human immunodeficiency virus type 1 (HIV-1) replication in HIV-1-infected CD4+ T cells and macrophages.

Zheng N, Fujiwara M, Ueno T, Oka S, Takiguchi M.

J Virol. 2009 Aug;83(15):7668-77. doi: 10.1128/JVI.00513-09. Epub 2009 May 20.

PMID:
19457989
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide.

Sepúlveda-Crespo D, Lorente R, Leal M, Gómez R, De la Mata FJ, Jiménez JL, Muñoz-Fernández MÁ.

Nanomedicine. 2014 Apr;10(3):609-18. doi: 10.1016/j.nano.2013.10.002. Epub 2013 Oct 14.

PMID:
24135563
[PubMed - indexed for MEDLINE]
11.

T-tropic human immunodeficiency virus (HIV) type 1 Nef protein enters human monocyte-macrophages and induces resistance to HIV replication: a possible mechanism of HIV T-tropic emergence in AIDS.

Alessandrini L, Santarcangelo AC, Olivetta E, Ferrantelli F, d'Aloja P, Pugliese K, Pelosi E, Chelucci C, Mattia G, Peschle C, Verani P, Federico M.

J Gen Virol. 2000 Dec;81(Pt 12):2905-17.

PMID:
11086122
[PubMed - indexed for MEDLINE]
Free Article
12.

Carbosilane dendrimers to transfect human astrocytes with small interfering RNA targeting human immunodeficiency virus.

Jiménez JL, Clemente MI, Weber ND, Sanchez J, Ortega P, de la Mata FJ, Gómez R, García D, López-Fernández LA, Muñoz-Fernández MA.

BioDrugs. 2010 Oct 1;24(5):331-43. doi: 10.2165/11538400-000000000-00000.

PMID:
20795754
[PubMed - indexed for MEDLINE]
13.

Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1.

Shcharbin D, Pedziwiatr E, Nowacka O, Kumar M, Zaborski M, Ortega P, de la Mata FJ, Gómez R, Muñoz-Fernandez MA, Bryszewska M.

Colloids Surf B Biointerfaces. 2011 Apr 1;83(2):388-91. doi: 10.1016/j.colsurfb.2010.11.009. Epub 2010 Nov 16.

PMID:
21145713
[PubMed - indexed for MEDLINE]
14.

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages.

Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB.

J Exp Med. 1994 Jan 1;179(1):101-13.

PMID:
8270859
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The nef gene controls syncytium formation in primary human lymphocytes and macrophages infected by HIV type 1.

Meylan PR, Baumgartner M, Ciuffi A, Munoz M, Sahli R.

AIDS Res Hum Retroviruses. 1998 Nov 20;14(17):1531-42.

PMID:
9840286
[PubMed - indexed for MEDLINE]
16.

Interaction of cationic carbosilane dendrimers and their complexes with siRNA with erythrocytes and red blood cell ghosts.

Wrobel D, Kolanowska K, Gajek A, Gomez-Ramirez R, de la Mata J, Pedziwiatr-Werbicka E, Klajnert B, Waczulikova I, Bryszewska M.

Biochim Biophys Acta. 2014 Mar;1838(3):882-9. doi: 10.1016/j.bbamem.2013.11.017. Epub 2013 Dec 5. Review.

PMID:
24316171
[PubMed - indexed for MEDLINE]
17.

Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence.

Mahlknecht U, Deng C, Lu MC, Greenough TC, Sullivan JL, O'Brien WA, Herbein G.

J Immunol. 2000 Dec 1;165(11):6437-46.

PMID:
11086083
[PubMed - indexed for MEDLINE]
Free Article
18.

Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity.

Posadas I, López-Hernández B, Clemente MI, Jiménez JL, Ortega P, de la Mata J, Gómez R, Muñoz-Fernández MA, Ceña V.

Pharm Res. 2009 May;26(5):1181-91. doi: 10.1007/s11095-009-9839-9. Epub 2009 Feb 4.

PMID:
19191011
[PubMed - indexed for MEDLINE]
19.

Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages.

Yamamoto T, Miyoshi H, Yamamoto N, Yamamoto N, Inoue J, Tsunetsugu-Yokota Y.

Blood. 2006 Nov 15;108(10):3305-12. Epub 2006 Jul 20.

PMID:
16857988
[PubMed - indexed for MEDLINE]
Free Article
20.

Novel 'Si-C' carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells.

Pedziwiatr-Werbicka E, Fuentes E, Dzmitruk V, Sánchez-Nieves J, Sudas M, Drozd E, Shakhbazau A, Shcharbin D, de la Mata FJ, Gomez-Ramirez R, Munoz-Fernandez MA, Bryszewska M.

Colloids Surf B Biointerfaces. 2013 Sep 1;109:183-9. doi: 10.1016/j.colsurfb.2013.03.045. Epub 2013 Apr 8.

PMID:
23643914
[PubMed - indexed for MEDLINE]
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