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Items: 1 to 20 of 134

1.
2.

Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.

Caton AJ, Kropf E, Simons DM, Aitken M, Weissler KA, Jordan MS.

Eur J Immunol. 2014 Mar;44(3):785-93. doi: 10.1002/eji.201343767. Epub 2013 Dec 27.

3.

Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.

Picca CC, Oh S, Panarey L, Aitken M, Basehoar A, Caton AJ.

Eur J Immunol. 2009 Dec;39(12):3301-6. doi: 10.1002/eji.200939709.

4.

CD4⁺CD25⁺Foxp3⁺ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletion.

Cozzo Picca C, Simons DM, Oh S, Aitken M, Perng OA, Mergenthaler C, Kropf E, Erikson J, Caton AJ.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14890-5. doi: 10.1073/pnas.1103810108. Epub 2011 Aug 22.

5.

Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells.

Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C.

J Immunol. 2007 Jun 1;178(11):7032-41.

6.

Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.

Coutinho A, Caramalho I, Seixas E, Demengeot J.

Curr Top Microbiol Immunol. 2005;293:43-71. Review.

PMID:
15981475
7.

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota.

Cebula A, Seweryn M, Rempala GA, Pabla SS, McIndoe RA, Denning TL, Bry L, Kraj P, Kisielow P, Ignatowicz L.

Nature. 2013 May 9;497(7448):258-62. doi: 10.1038/nature12079. Epub 2013 Apr 28.

8.

Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes.

Wirnsberger G, Hinterberger M, Klein L.

Immunol Cell Biol. 2011 Jan;89(1):45-53. doi: 10.1038/icb.2010.123. Epub 2010 Nov 2. Review.

PMID:
21042335
9.

CD4+CD25+ regulatory T cell repertoire formation shaped by differential presentation of peptides from a self-antigen.

Larkin J 3rd, Rankin AL, Picca CC, Riley MP, Jenks SA, Sant AJ, Caton AJ.

J Immunol. 2008 Feb 15;180(4):2149-57.

10.

A signal integration model of thymic selection and natural regulatory T cell commitment.

Khailaie S, Robert PA, Toker A, Huehn J, Meyer-Hermann M.

J Immunol. 2014 Dec 15;193(12):5983-96. doi: 10.4049/jimmunol.1400889. Epub 2014 Nov 12.

11.

A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease.

Killebrew JR, Perdue N, Kwan A, Thornton AM, Shevach EM, Campbell DJ.

J Immunol. 2011 Jul 15;187(2):861-9. doi: 10.4049/jimmunol.1004009. Epub 2011 Jun 20.

12.

Structural basis for self-recognition by autoimmune T-cell receptors.

Yin Y, Li Y, Mariuzza RA.

Immunol Rev. 2012 Nov;250(1):32-48. doi: 10.1111/imr.12002. Review.

PMID:
23046121
13.

Induction of self-antigen-specific Foxp3+ regulatory T cells in the periphery by lymphodepletion treatment with anti-mouse thymocyte globulin in mice.

Lu Y, Suzuki J, Guillioli M, Umland O, Chen Z.

Immunology. 2011 Sep;134(1):50-9. doi: 10.1111/j.1365-2567.2011.03466.x. Epub 2011 Jun 29.

14.

Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo.

Weissler KA, Garcia V, Kropf E, Aitken M, Bedoya F, Wolf AI, Erikson J, Caton AJ.

J Immunol. 2015 Apr 15;194(8):3784-97. doi: 10.4049/jimmunol.1402960. Epub 2015 Mar 16.

15.

Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection.

Picca CC, Larkin J 3rd, Boesteanu A, Lerman MA, Rankin AL, Caton AJ.

Immunol Rev. 2006 Aug;212:74-85. Review.

PMID:
16903907
16.

A role for accessibility to self-peptide-self-MHC complexes in intrathymic negative selection.

Viret C, Sant'Angelo DB, He X, Ramaswamy H, Janeway CA Jr.

J Immunol. 2001 Apr 1;166(7):4429-37.

17.

The T-cell receptor repertoire of regulatory T cells.

Pacholczyk R, Kern J.

Immunology. 2008 Dec;125(4):450-8. doi: 10.1111/j.1365-2567.2008.02992.x. Review.

18.

Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

Ribot J, Enault G, Pilipenko S, Huchenq A, Calise M, Hudrisier D, Romagnoli P, van Meerwijk JP.

J Immunol. 2007 Nov 15;179(10):6741-8.

19.

A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance.

Feng Y, van der Veeken J, Shugay M, Putintseva EV, Osmanbeyoglu HU, Dikiy S, Hoyos BE, Moltedo B, Hemmers S, Treuting P, Leslie CS, Chudakov DM, Rudensky AY.

Nature. 2015 Dec 3;528(7580):132-6. doi: 10.1038/nature16141. Epub 2015 Nov 25.

20.

Effects and regulation of autoreactive CD8+ T cells in a transgenic mouse model of autoimmune hepatitis.

Zierden M, Kühnen E, Odenthal M, Dienes HP.

Gastroenterology. 2010 Sep;139(3):975-86, 986.e1-3. doi: 10.1053/j.gastro.2010.05.075. Epub 2010 Jun 2.

PMID:
20639127
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