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Results: 1 to 20 of 86

1.

IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1.

Faye MD, Beug ST, Graber TE, Earl N, Xiang X, Wild B, Langlois S, Michaud J, Cowan KN, Korneluk RG, Holcik M.

Oncogene. 2014 Apr 7. doi: 10.1038/onc.2014.90. [Epub ahead of print]

PMID:
24704827
[PubMed - as supplied by publisher]
2.

Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.

Feltham R, Moulin M, Vince JE, Mace PD, Wong WW, Anderton H, Day CL, Vaux DL, Silke J.

J Biol Chem. 2010 Jun 4;285(23):17525-36. doi: 10.1074/jbc.M109.087635. Epub 2010 Mar 30.

PMID:
20356846
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.

Gordon GJ, Mani M, Mukhopadhyay L, Dong L, Yeap BY, Sugarbaker DJ, Bueno R.

J Pathol. 2007 Mar;211(4):439-46.

PMID:
17253597
[PubMed - indexed for MEDLINE]
4.

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P, McKinlay M, Benetatos CA, Condon SM, Chunduru SK, Yeoh G, Brink R, Vaux DL, Silke J.

J Cell Biol. 2008 Jul 14;182(1):171-84. doi: 10.1083/jcb.200801010. Epub 2008 Jul 7.

PMID:
18606850
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.

Allensworth JL, Sauer SJ, Lyerly HK, Morse MA, Devi GR.

Breast Cancer Res Treat. 2013 Jan;137(2):359-71. doi: 10.1007/s10549-012-2352-6. Epub 2012 Dec 7.

PMID:
23225169
[PubMed - indexed for MEDLINE]
6.

Smac mimetic primes apoptosis-resistant acute myeloid leukaemia cells for cytarabine-induced cell death by triggering necroptosis.

Chromik J, Safferthal C, Serve H, Fulda S.

Cancer Lett. 2014 Mar 1;344(1):101-9. doi: 10.1016/j.canlet.2013.10.018. Epub 2013 Oct 30.

PMID:
24184825
[PubMed - indexed for MEDLINE]
7.

cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation.

Marivin A, Berthelet J, Cartier J, Paul C, Gemble S, Morizot A, Boireau W, Saleh M, Bertoglio J, Solary E, Dubrez L.

Oncogene. 2013 Nov 25. doi: 10.1038/onc.2013.499. [Epub ahead of print]

PMID:
24276241
[PubMed - as supplied by publisher]
8.

miR-625 suppresses tumour migration and invasion by targeting IGF2BP1 in hepatocellular carcinoma.

Zhou X, Zhang CZ, Lu SX, Chen GG, Li LZ, Liu LL, Yi C, Fu J, Hu W, Wen JM, Yun JP.

Oncogene. 2014 Mar 17. doi: 10.1038/onc.2014.35. [Epub ahead of print]

PMID:
24632613
[PubMed - as supplied by publisher]
9.

RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.

Basit F, Humphreys R, Fulda S.

J Biol Chem. 2012 Nov 9;287(46):38767-77. doi: 10.1074/jbc.M112.398966. Epub 2012 Aug 27.

PMID:
22927431
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.

Taylor JG 6th, Cheuk AT, Tsang PS, Chung JY, Song YK, Desai K, Yu Y, Chen QR, Shah K, Youngblood V, Fang J, Kim SY, Yeung C, Helman LJ, Mendoza A, Ngo V, Staudt LM, Wei JS, Khanna C, Catchpoole D, Qualman SJ, Hewitt SM, Merlino G, Chanock SJ, Khan J.

J Clin Invest. 2009 Nov;119(11):3395-407. doi: 10.1172/JCI39703. Epub 2009 Oct 5.

PMID:
19809159
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.

Darding M, Feltham R, Tenev T, Bianchi K, Benetatos C, Silke J, Meier P.

Cell Death Differ. 2011 Aug;18(8):1376-86. doi: 10.1038/cdd.2011.10. Epub 2011 Feb 18.

PMID:
21331077
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer.

Foster FM, Owens TW, Tanianis-Hughes J, Clarke RB, Brennan K, Bundred NJ, Streuli CH.

Breast Cancer Res. 2009;11(3):R41. doi: 10.1186/bcr2328. Epub 2009 Jun 29.

PMID:
19563669
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.

Wang MY, Chen PS, Prakash E, Hsu HC, Huang HY, Lin MT, Chang KJ, Kuo ML.

Cancer Res. 2009 Apr 15;69(8):3482-91. doi: 10.1158/0008-5472.CAN-08-2524. Epub 2009 Apr 7.

PMID:
19351859
[PubMed - indexed for MEDLINE]
Free Article
14.

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.

Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, Lacasse EC, Waring J, Korneluk RG.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11778-83. doi: 10.1073/pnas.0711122105. Epub 2008 Aug 12.

PMID:
18697935
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents.

Holt SV, Brookes KE, Dive C, Makin GW.

Oncol Rep. 2011 Apr;25(4):1177-81. doi: 10.3892/or.2011.1167. Epub 2011 Jan 31.

PMID:
21286665
[PubMed - indexed for MEDLINE]
16.

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.

Vanlangenakker N, Vanden Berghe T, Bogaert P, Laukens B, Zobel K, Deshayes K, Vucic D, Fulda S, Vandenabeele P, Bertrand MJ.

Cell Death Differ. 2011 Apr;18(4):656-65. doi: 10.1038/cdd.2010.138. Epub 2010 Nov 5.

PMID:
21052097
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.

Vischioni B, Giaccone G, Span SW, Kruyt FA, Rodriguez JA.

Exp Cell Res. 2004 Aug 15;298(2):535-48.

PMID:
15265700
[PubMed - indexed for MEDLINE]
18.

Dexamethasone inhibits TNF-alpha-induced apoptosis and IAP protein downregulation in MCF-7 cells.

Messmer UK, Pereda-Fernandez C, Manderscheid M, Pfeilschifter J.

Br J Pharmacol. 2001 Jun;133(4):467-76.

PMID:
11399663
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

MI-63: a novel small-molecule inhibitor targets MDM2 and induces apoptosis in embryonal and alveolar rhabdomyosarcoma cells with wild-type p53.

Canner JA, Sobo M, Ball S, Hutzen B, DeAngelis S, Willis W, Studebaker AW, Ding K, Wang S, Yang D, Lin J.

Br J Cancer. 2009 Sep 1;101(5):774-81. doi: 10.1038/sj.bjc.6605199.

PMID:
19707204
[PubMed - indexed for MEDLINE]
Free PMC Article

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