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Items: 1 to 20 of 76

1.

The right choice of antihypertensives protects primary human hepatocytes from ethanol- and recombinant human TGF-β1-induced cellular damage.

Ehnert S, Lukoschek T, Bachmann A, Martínez Sánchez JJ, Damm G, Nussler NC, Pscherer S, Stöckle U, Dooley S, Mueller S, Nussler AK.

Hepat Med. 2013 Mar 22;5:31-41. doi: 10.2147/HMER.S38754. eCollection 2013.

2.

TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I.

Ciuclan L, Ehnert S, Ilkavets I, Weng HL, Gaitantzi H, Tsukamoto H, Ueberham E, Meindl-Beinker NM, Singer MV, Breitkopf K, Dooley S.

J Hepatol. 2010 Mar;52(3):407-16. doi: 10.1016/j.jhep.2009.12.003. Epub 2010 Jan 6.

PMID:
20129692
3.

The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress.

Zeng T, Zhang CL, Song FY, Zhao XL, Yu LH, Zhu ZP, Xie KQ.

Biochim Biophys Acta. 2013 Oct;1830(10):4848-59. doi: 10.1016/j.bbagen.2013.06.028. Epub 2013 Jun 28.

PMID:
23816986
4.

Induction of heme oxygenase-1 in human hepatocytes to protect them from ethanol-induced cytotoxicity.

Liu LG, Yan H, Zhang W, Yao P, Zhang XP, Sun XF, Nussler AK.

Biomed Environ Sci. 2004 Sep;17(3):315-26.

PMID:
15602829
5.

BRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responses.

Li H, Sekine M, Seng S, Avraham S, Avraham HK.

PLoS One. 2009 Sep 21;4(9):e7091. doi: 10.1371/journal.pone.0007091.

6.

Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1.

Zhuge J, Cederbaum AI.

Free Radic Biol Med. 2006 Oct 1;41(7):1100-12. Epub 2006 Jul 4.

PMID:
16962935
7.

Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways.

Yao P, Nussler A, Liu L, Hao L, Song F, Schirmeier A, Nussler N.

J Hepatol. 2007 Aug;47(2):253-61. Epub 2007 Mar 7.

PMID:
17433488
8.

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

Jung Y, Brown KD, Witek RP, Omenetti A, Yang L, Vandongen M, Milton RJ, Hines IN, Rippe RA, Spahr L, Rubbia-Brandt L, Diehl AM.

Gastroenterology. 2008 May;134(5):1532-43. doi: 10.1053/j.gastro.2008.02.022. Epub 2008 Feb 14.

9.
10.

TGF-beta activated Smad signalling leads to a Smad3-mediated down-regulation of DSPP in an odontoblast cell line.

He WX, Niu ZY, Zhao SL, Jin WL, Gao J, Smith AJ.

Arch Oral Biol. 2004 Nov;49(11):911-8.

PMID:
15353247
11.

Antroquinonol from ethanolic extract of mycelium of Antrodia cinnamomea protects hepatic cells from ethanol-induced oxidative stress through Nrf-2 activation.

Kumar KJ, Chu FH, Hsieh HW, Liao JW, Li WH, Lin JC, Shaw JF, Wang SY.

J Ethnopharmacol. 2011 Jun 14;136(1):168-77. doi: 10.1016/j.jep.2011.04.030. Epub 2011 Apr 20.

PMID:
21540101
12.

Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway.

Li Y, Gao C, Shi Y, Tang Y, Liu L, Xiong T, Du M, Xing M, Liu L, Yao P.

Toxicol Appl Pharmacol. 2013 Nov 15;273(1):53-8. doi: 10.1016/j.taap.2013.08.019. Epub 2013 Aug 28.

PMID:
23994557
13.

Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell.

Huang D, Wang Y, Wang L, Zhang F, Deng S, Wang R, Zhang Y, Huang K.

PLoS One. 2011;6(10):e27123. doi: 10.1371/journal.pone.0027123. Epub 2011 Oct 31.

14.

Transforming growth factor-beta suppressed Id-1 Expression in a smad3-dependent manner in LoVo cells.

Song H, Guo B, Zhang J, Song C.

Anat Rec (Hoboken). 2010 Jan;293(1):42-7. doi: 10.1002/ar.21012.

15.

Heme oxygenase-1 upregulated by Ginkgo biloba extract: potential protection against ethanol-induced oxidative liver damage.

Yao P, Li K, Song F, Zhou S, Sun X, Zhang X, Nüssler AK, Liu L.

Food Chem Toxicol. 2007 Aug;45(8):1333-42. Epub 2007 Jan 31.

PMID:
17467134
16.

Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-kappaB pathways in human lung epithelial cells.

Lin CC, Chiang LL, Lin CH, Shih CH, Liao YT, Hsu MJ, Chen BC.

Eur J Pharmacol. 2007 Apr 10;560(2-3):101-9. Epub 2007 Jan 27.

PMID:
17307160
17.

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1.

Ungefroren H, Groth S, Sebens S, Lehnert H, Gieseler F, Fändrich F.

Mol Cancer. 2011 May 30;10:67. doi: 10.1186/1476-4598-10-67.

19.
20.

Effect of salvianolic acid B on Smad3 expression in hepatic stellate cells.

Zhao JF, Liu CH, Hu YY, Xu LM, Liu P, Liu C.

Hepatobiliary Pancreat Dis Int. 2004 Feb;3(1):102-5.

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