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Items: 1 to 20 of 147

1.

A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptor.

Jun LS, Showalter AD, Ali N, Dai F, Ma W, Coskun T, Ficorilli JV, Wheeler MB, Michael MD, Sloop KW.

PLoS One. 2014 Apr 2;9(4):e93746. doi: 10.1371/journal.pone.0093746. eCollection 2014. Erratum in: PLoS One. 2015;10(7):e0132875.

2.

Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway.

Thompson A, Kanamarlapudi V.

Biochem Pharmacol. 2015 Jan 1;93(1):72-84. doi: 10.1016/j.bcp.2014.10.015. Epub 2014 Nov 7.

PMID:
25449603
3.
4.

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

Lamont BJ, Li Y, Kwan E, Brown TJ, Gaisano H, Drucker DJ.

J Clin Invest. 2012 Jan;122(1):388-402. doi: 10.1172/JCI42497. Epub 2011 Dec 19.

5.

The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties.

Irwin DM, Satkunarajah M, Wen Y, Brubaker PL, Pederson RA, Wheeler MB.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7915-20.

6.

An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis.

Baggio LL, Huang Q, Cao X, Drucker DJ.

Gastroenterology. 2008 Apr;134(4):1137-47. doi: 10.1053/j.gastro.2008.01.017. Epub 2008 Jan 11.

PMID:
18313669
7.

The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice.

Maida A, Lovshin JA, Baggio LL, Drucker DJ.

Endocrinology. 2008 Nov;149(11):5670-8. doi: 10.1210/en.2008-0336. Epub 2008 Jul 31.

PMID:
18669601
8.

Bioactive GLP-1 in gut, receptor expression in pancreas, and insulin response to GLP-1 in diabetes-prone rats.

Valverde I, Wang GS, Burghardt K, Kauri LM, Redondo A, Acitores A, Villanueva-Peñacarrillo ML, Courtois P, Sener A, Cancelas J, Malaisse WJ, Scott FW.

Endocrine. 2004 Feb;23(1):77-84.

PMID:
15034199
9.

Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.

Nakashima R, Yano T, Ogawa J, Tanaka N, Toda N, Yoshida M, Takano R, Inoue M, Honda T, Kume S, Matsumoto K.

Eur J Pharmacol. 2014 Aug 15;737:194-201. doi: 10.1016/j.ejphar.2014.05.014. Epub 2014 May 22.

PMID:
24858371
10.

18F-Labeled exendin(9-39).

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Feb 09 [updated 2012 May 17].

11.
12.

Mechanisms of action of glucagon-like peptide 1 in the pancreas.

Doyle ME, Egan JM.

Pharmacol Ther. 2007 Mar;113(3):546-93. Epub 2006 Dec 28. Review.

13.

Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice.

Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE.

Am J Physiol Endocrinol Metab. 2012 Feb 1;302(3):E334-43. doi: 10.1152/ajpendo.00409.2011. Epub 2011 Nov 15.

15.

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

Pederson RA, Satkunarajah M, McIntosh CH, Scrocchi LA, Flamez D, Schuit F, Drucker DJ, Wheeler MB.

Diabetes. 1998 Jul;47(7):1046-52.

PMID:
9648827
16.

Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking.

Roed SN, Nøhr AC, Wismann P, Iversen H, Bräuner-Osborne H, Knudsen SM, Waldhoer M.

J Biol Chem. 2015 Jan 9;290(2):1233-43. doi: 10.1074/jbc.M114.592436. Epub 2014 Dec 1.

18.

Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.

Gu W, Winters KA, Motani AS, Komorowski R, Zhang Y, Liu Q, Wu X, Rulifson IC, Sivits G Jr, Graham M, Yan H, Wang P, Moore S, Meng T, Lindberg RA, Véniant MM.

Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E624-32. doi: 10.1152/ajpendo.00102.2010. Epub 2010 Jul 20.

19.

The peptide-hormone glucagon-like peptide-1 activates cAMP and inhibits growth of breast cancer cells.

Ligumsky H, Wolf I, Israeli S, Haimsohn M, Ferber S, Karasik A, Kaufman B, Rubinek T.

Breast Cancer Res Treat. 2012 Apr;132(2):449-61. doi: 10.1007/s10549-011-1585-0. Epub 2011 Jun 3.

PMID:
21638053
20.

Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation.

Thompson A, Stephens JW, Bain SC, Kanamarlapudi V.

PLoS One. 2016 Apr 21;11(4):e0154229. doi: 10.1371/journal.pone.0154229. eCollection 2016.

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