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Items: 1 to 20 of 105

1.

RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.

Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT.

J Biol Chem. 2014 May 16;289(20):13701-5. doi: 10.1074/jbc.C114.548982. Epub 2014 Apr 1.

2.

Activation of the NLRP3 inflammasome by group B streptococci.

Costa A, Gupta R, Signorino G, Malara A, Cardile F, Biondo C, Midiri A, Galbo R, Trieu-Cuot P, Papasergi S, Teti G, Henneke P, Mancuso G, Golenbock DT, Beninati C.

J Immunol. 2012 Feb 15;188(4):1953-60. doi: 10.4049/jimmunol.1102543. Epub 2012 Jan 16.

3.

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages.

Huang TT, Ojcius DM, Young JD, Wu YH, Ko YF, Wong TY, Wu CY, Lu CC, Lai HC.

PLoS One. 2012;7(7):e41383. doi: 10.1371/journal.pone.0041383. Epub 2012 Jul 23.

4.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

5.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
6.

IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection.

Ketelut-Carneiro N, Silva GK, Rocha FA, Milanezi CM, Cavalcanti-Neto FF, Zamboni DS, Silva JS.

J Immunol. 2015 May 1;194(9):4507-17. doi: 10.4049/jimmunol.1402321. Epub 2015 Mar 30.

PMID:
25825440
7.

Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation.

Orlowski GM, Colbert JD, Sharma S, Bogyo M, Robertson SA, Rock KL.

J Immunol. 2015 Aug 15;195(4):1685-97. doi: 10.4049/jimmunol.1500509. Epub 2015 Jul 20. Erratum in: J Immunol. 2016 Jan 1;196(1):503.

PMID:
26195813
8.

The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity.

Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T.

PLoS Pathog. 2012;8(7):e1002812. doi: 10.1371/journal.ppat.1002812. Epub 2012 Jul 19.

9.

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

Meixenberger K, Pache F, Eitel J, Schmeck B, Hippenstiel S, Slevogt H, N'Guessan P, Witzenrath M, Netea MG, Chakraborty T, Suttorp N, Opitz B.

J Immunol. 2010 Jan 15;184(2):922-30. doi: 10.4049/jimmunol.0901346. Epub 2009 Dec 11.

10.

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.

Rajamäki K, Nordström T, Nurmi K, Åkerman KE, Kovanen PT, Öörni K, Eklund KK.

J Biol Chem. 2013 May 10;288(19):13410-9. doi: 10.1074/jbc.M112.426254. Epub 2013 Mar 25.

11.

Lipopolysaccharide/adenosine triphosphate induces IL‑1β and IL-18 secretion through the NLRP3 inflammasome in RAW264.7 murine macrophage cells.

Xie Q, Shen WW, Zhong J, Huang C, Zhang L, Li J.

Int J Mol Med. 2014 Jul;34(1):341-9. doi: 10.3892/ijmm.2014.1755. Epub 2014 Apr 24.

PMID:
24789624
12.

High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1β secretion.

Cui H, Wu W, Okuhira K, Miyazawa K, Hattori T, Sai K, Naito M, Suzuki K, Nishimura T, Sakamoto Y, Ogata A, Maeno T, Inomata A, Nakae D, Hirose A, Nishimaki-Mogami T.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):593-9. doi: 10.1016/j.bbrc.2014.08.118. Epub 2014 Aug 30.

PMID:
25181346
13.

Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation.

Heid ME, Keyel PA, Kamga C, Shiva S, Watkins SC, Salter RD.

J Immunol. 2013 Nov 15;191(10):5230-8. doi: 10.4049/jimmunol.1301490. Epub 2013 Oct 2.

14.

Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome.

Kebaier C, Chamberland RR, Allen IC, Gao X, Broglie PM, Hall JD, Jania C, Doerschuk CM, Tilley SL, Duncan JA.

J Infect Dis. 2012 Mar 1;205(5):807-17. doi: 10.1093/infdis/jir846. Epub 2012 Jan 25.

15.

Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection.

Chen CC, Tsai SH, Lu CC, Hu ST, Wu TS, Huang TT, Saïd-Sadier N, Ojcius DM, Lai HC.

PLoS One. 2012;7(4):e36292. doi: 10.1371/journal.pone.0036292. Epub 2012 Apr 30.

16.

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G.

J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7.

17.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

18.

Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury.

Wu J, Yan Z, Schwartz DE, Yu J, Malik AB, Hu G.

J Immunol. 2013 Apr 1;190(7):3590-9. doi: 10.4049/jimmunol.1200860. Epub 2013 Feb 22.

19.

Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome.

Ito M, Yanagi Y, Ichinohe T.

PLoS Pathog. 2012;8(8):e1002857. doi: 10.1371/journal.ppat.1002857. Epub 2012 Aug 9.

20.

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1.

Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK.

Immunol Cell Biol. 2012 Jul;90(6):601-10. doi: 10.1038/icb.2011.72. Epub 2011 Aug 30.

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