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Results: 1 to 20 of 96

1.

Inhibition of intimal hyperplasia in murine aortic allografts by the oral administration of the transforming growth factor-beta receptor I kinase inhibitor SD-208.

Sun Y, Ye P, Wu J, Liu Z, Zhang A, Ren L, Cheng C, Huang X, Wang K, Deng P, Wu C, Yue Z, Xia J.

J Heart Lung Transplant. 2014 Jun;33(6):654-61. doi: 10.1016/j.healun.2014.02.020. Epub 2014 Feb 21.

PMID:
24685405
[PubMed - in process]
2.

TGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation.

Tsai S, Hollenbeck ST, Ryer EJ, Edlin R, Yamanouchi D, Kundi R, Wang C, Liu B, Kent KC.

Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H540-9. doi: 10.1152/ajpheart.91478.2007. Epub 2009 Jun 12.

PMID:
19525370
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury.

Kobayashi K, Yokote K, Fujimoto M, Yamashita K, Sakamoto A, Kitahara M, Kawamura H, Maezawa Y, Asaumi S, Tokuhisa T, Mori S, Saito Y.

Circ Res. 2005 Apr 29;96(8):904-12. Epub 2005 Mar 24.

PMID:
15790953
[PubMed - indexed for MEDLINE]
Free Article
4.

Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells.

Zhang F, Tsai S, Kato K, Yamanouchi D, Wang C, Rafii S, Liu B, Kent KC.

J Biol Chem. 2009 Jun 26;284(26):17564-74. doi: 10.1074/jbc.M109.013987. Epub 2009 Apr 30.

PMID:
19406748
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

CC chemokine receptor-1 activates intimal smooth muscle-like cells in graft arterial disease.

Shimizu K, Minami M, Shubiki R, Lopez-Ilasaca M, MacFarlane L, Asami Y, Li Y, Mitchell RN, Libby P.

Circulation. 2009 Nov 3;120(18):1800-13. doi: 10.1161/CIRCULATIONAHA.109.859595. Epub 2009 Oct 19.

PMID:
19841301
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGF.

Kundi R, Hollenbeck ST, Yamanouchi D, Herman BC, Edlin R, Ryer EJ, Wang C, Tsai S, Liu B, Kent KC.

Cardiovasc Res. 2009 Nov 1;84(2):326-35. doi: 10.1093/cvr/cvp220. Epub 2009 Jul 1.

PMID:
19570811
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Runx2/Smad3 complex negatively regulates TGF-β-induced connective tissue growth factor gene expression in vascular smooth muscle cells.

Ohyama Y, Tanaka T, Shimizu T, Matsui H, Sato H, Koitabashi N, Doi H, Iso T, Arai M, Kurabayashi M.

J Atheroscler Thromb. 2012;19(1):23-35. Epub 2011 Oct 8.

PMID:
21986102
[PubMed - indexed for MEDLINE]
Free Article
8.

c-Ski inhibits the proliferation of vascular smooth muscle cells via suppressing Smad3 signaling but stimulating p38 pathway.

Li J, Li P, Zhang Y, Li GB, Zhou YG, Yang K, Dai SS.

Cell Signal. 2013 Jan;25(1):159-67. doi: 10.1016/j.cellsig.2012.09.001. Epub 2012 Sep 7.

PMID:
22986000
[PubMed - indexed for MEDLINE]
9.

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3.

Fu M, Zhang J, Zhu X, Myles DE, Willson TM, Liu X, Chen YE.

J Biol Chem. 2001 Dec 7;276(49):45888-94. Epub 2001 Oct 5.

PMID:
11590167
[PubMed - indexed for MEDLINE]
Free Article
10.

Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury.

Lv L, Zhang J, Wang P, Meng Q, Liang W, Zhang L.

J Vasc Surg. 2014 Feb;59(2):500-9. doi: 10.1016/j.jvs.2013.03.049. Epub 2013 Jun 4.

PMID:
23755975
[PubMed - indexed for MEDLINE]
11.

Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.

Yang F, Chung AC, Huang XR, Lan HY.

Hypertension. 2009 Oct;54(4):877-84. doi: 10.1161/HYPERTENSIONAHA.109.136531. Epub 2009 Aug 10.

PMID:
19667256
[PubMed - indexed for MEDLINE]
Free Article
12.

Macrophage depletion reduces monocyte chemotactic protein-1 and transforming growth factor-beta1 in healing rat vein grafts.

Wolff RA, Tomas JJ, Hullett DA, Stark VE, van Rooijen N, Hoch JR.

J Vasc Surg. 2004 Apr;39(4):878-88.

PMID:
15071458
[PubMed - indexed for MEDLINE]
Free Article
13.

Established neointimal hyperplasia in vein grafts expands via TGF-beta-mediated progressive fibrosis.

Jiang Z, Tao M, Omalley KA, Wang D, Ozaki CK, Berceli SA.

Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1200-7. doi: 10.1152/ajpheart.00268.2009. Epub 2009 Jul 17.

PMID:
19617405
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.

Razuvaev A, Henderson B, Girnita L, Larsson O, Axelson M, Hedin U, Roy J.

J Vasc Surg. 2007 Jul;46(1):108-15.

PMID:
17606126
[PubMed - indexed for MEDLINE]
Free Article
16.

Antisense to transforming growth factor-beta1 messenger RNA reduces vein graft intimal hyperplasia and monocyte chemotactic protein 1.

Wolff RA, Ryomoto M, Stark VE, Malinowski R, Tomas JJ, Stinauer MA, Hullett DA, Hoch JR.

J Vasc Surg. 2005 Mar;41(3):498-508.

PMID:
15838486
[PubMed - indexed for MEDLINE]
Free Article
17.

Estrogen replacement inhibits intimal hyperplasia and the accumulation and effects of transforming growth factor beta1.

Selzman CH, Gaynor JS, Turner AS, Whitehill TA, Horwitz LD, Harken AH.

J Surg Res. 1998 Dec;80(2):380-5.

PMID:
9878341
[PubMed - indexed for MEDLINE]
18.

[Expression of early growth response gene-1 and its correlative genes in autogenous vein graft and significance thereof: an experiment with rats].

Liu CW, Hu XH, Yang J, Zhang Q, Zhang XS, Duan ZQ.

Zhonghua Yi Xue Za Zhi. 2005 Dec 21;85(48):3414-8. Chinese.

PMID:
16409863
[PubMed - indexed for MEDLINE]
19.

SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo.

Uhl M, Aulwurm S, Wischhusen J, Weiler M, Ma JY, Almirez R, Mangadu R, Liu YW, Platten M, Herrlinger U, Murphy A, Wong DH, Wick W, Higgins LS, Weller M.

Cancer Res. 2004 Nov 1;64(21):7954-61.

PMID:
15520202
[PubMed - indexed for MEDLINE]
Free Article
20.

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S.

Hepatology. 2007 Oct;46(4):1257-70.

PMID:
17657819
[PubMed - indexed for MEDLINE]

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