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Items: 1 to 20 of 112

1.

Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.

Wang L, Wang C, Peng J, Liu Q, Meng Q, Sun H, Huo X, Sun P, Yang X, Zhen Y, Liu K.

Toxicol Appl Pharmacol. 2014 Jun 1;277(2):146-54. doi: 10.1016/j.taap.2014.03.013. Epub 2014 Mar 26.

PMID:
24680847
2.

Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition.

Wang L, Meng Q, Wang C, Liu Q, Peng J, Huo X, Sun H, Ma X, Liu K.

J Nat Prod. 2013 May 24;76(5):909-14. doi: 10.1021/np400071c. Epub 2013 Apr 26.

PMID:
23621869
4.

Glutamine and arginine improve permeability and tight junction protein expression in methotrexate-treated Caco-2 cells.

Beutheu S, Ghouzali I, Galas L, Déchelotte P, Coëffier M.

Clin Nutr. 2013 Oct;32(5):863-9. doi: 10.1016/j.clnu.2013.01.014. Epub 2013 Feb 1.

PMID:
23428392
5.

Reversal effect of Dioscin on multidrug resistance in human hepatoma HepG2/adriamycin cells.

Sun BT, Zheng LH, Bao YL, Yu CL, Wu Y, Meng XY, Li YX.

Eur J Pharmacol. 2011 Mar 5;654(2):129-34. doi: 10.1016/j.ejphar.2010.12.018. Epub 2010 Dec 31.

PMID:
21195709
6.

Involvement of AP-1 and NF-κB in the up-regulation of P-gp in vinblastine resistant Caco-2 cells.

Chen Q, Bian Y, Zeng S.

Drug Metab Pharmacokinet. 2014;29(2):223-6. Epub 2013 Oct 1.

7.

Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation.

Kim HG, Hien TT, Han EH, Hwang YP, Choi JH, Kang KW, Kwon KI, Kim BH, Kim SK, Song GY, Jeong TC, Jeong HG.

Br J Pharmacol. 2011 Mar;162(5):1096-108. doi: 10.1111/j.1476-5381.2010.01101.x.

8.

Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats.

Zhu Y, Meng Q, Wang C, Liu Q, Huo X, Zhang A, Sun P, Sun H, Li H, Liu K.

Int J Pharm. 2014 Apr 25;465(1-2):368-77. doi: 10.1016/j.ijpharm.2014.02.020. Epub 2014 Feb 13.

PMID:
24530518
9.

Dietary transforming growth factor-beta 2 (TGF-β2) supplementation reduces methotrexate-induced intestinal mucosal injury in a rat.

Ben-Lulu S, Pollak Y, Mogilner J, Bejar J, G Coran A, Sukhotnik I.

PLoS One. 2012;7(9):e45221. doi: 10.1371/journal.pone.0045221. Epub 2012 Sep 12.

10.

The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells.

Yue GG, Cheng SW, Yu H, Xu ZS, Lee JK, Hon PM, Lee MY, Kennelly EJ, Deng G, Yeung SK, Cassileth BR, Fung KP, Leung PC, Lau CB.

J Med Food. 2012 Mar;15(3):242-52. doi: 10.1089/jmf.2011.1845. Epub 2011 Dec 19.

12.

Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells.

Cheng Z, Yang N, Liang W, Yan X, Li L, Pan L.

Leuk Lymphoma. 2012 Jul;53(7):1383-9. doi: 10.3109/10428194.2011.650695. Epub 2012 Jan 31.

PMID:
22185283
13.

Effect of transforming growth factor-alpha on enterocyte apoptosis is correlated with EGF receptor expression along the villus-crypt axis during methotrexate-induced intestinal mucositis in a rat.

Sukhotnik I, Shteinberg D, Ben Lulu S, Bashenko Y, Mogilner JG, Ure BM, Shaoul R, Coran AG.

Apoptosis. 2008 Nov;13(11):1344-55. doi: 10.1007/s10495-008-0258-x.

PMID:
18803016
14.

Methotrexate-loaded chitosan- and glycol chitosan-based nanoparticles: a promising strategy for the administration of the anticancer drug to brain tumors.

Trapani A, Denora N, Iacobellis G, Sitterberg J, Bakowsky U, Kissel T.

AAPS PharmSciTech. 2011 Dec;12(4):1302-11. doi: 10.1208/s12249-011-9695-x. Epub 2011 Sep 27.

15.

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.

Jia Y, Liu Z, Huo X, Wang C, Meng Q, Liu Q, Sun H, Sun P, Yang X, Shu X, Liu K.

Int J Pharm. 2015 Nov 10;495(1):588-98. doi: 10.1016/j.ijpharm.2015.09.042. Epub 2015 Sep 21.

PMID:
26394120
16.
17.

PSC833, cyclosporine analogue, downregulates MDR1 expression by activating JNK/c-Jun/AP-1 and suppressing NF-kappaB.

Bark H, Choi CH.

Cancer Chemother Pharmacol. 2010 May;65(6):1131-6. doi: 10.1007/s00280-009-1121-7. Epub 2009 Sep 18.

PMID:
19763573
18.

Prolonged use of aspirin alters human and rat intestinal cells and thereby limits the absorption of clopidogrel.

Jung KH, Chu K, Lee ST, Yoon HJ, Chang JY, Nam WS, Yoon SH, Cho JY, Yu KS, Jang IJ, Kim M, Lee SK, Roh JK.

Clin Pharmacol Ther. 2011 Oct;90(4):612-9. doi: 10.1038/clpt.2011.163. Epub 2011 Sep 7.

PMID:
21900887
19.

Overexpression of S100A4 in human cancer cell lines resistant to methotrexate.

Mencía N, Selga E, Rico I, de Almagro MC, Villalobos X, Ramirez S, Adan J, Hernández JL, Noé V, Ciudad CJ.

BMC Cancer. 2010 Jun 1;10:250. doi: 10.1186/1471-2407-10-250.

20.

Transforming growth factor-alpha stimulates enterocyte proliferation and accelerates intestinal recovery following methotrexate-induced intestinal mucositis in a rat and a cell culture model.

Sukhotnik I, Shteinberg D, Ben Lulu S, Bashenko Y, Mogilner JG, Ure BM, Shaoul R, Shamian B, Coran AG.

Pediatr Surg Int. 2008 Dec;24(12):1303-11. doi: 10.1007/s00383-008-2271-0.

PMID:
18956197
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