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A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis.

Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS.

Chembiochem. 2014 Mar 21;15(5):647-52.


Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis.

Gantt RW, Peltier-Pain P, Singh S, Zhou M, Thorson JS.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7648-53. doi: 10.1073/pnas.1220220110. Epub 2013 Apr 22.


Probing the aglycon promiscuity of an engineered glycosyltransferase.

Gantt RW, Goff RD, Williams GJ, Thorson JS.

Angew Chem Int Ed Engl. 2008;47(46):8889-92. doi: 10.1002/anie.200803508. No abstract available.


Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus.

Quirós LM, Aguirrezabalaga I, Olano C, Méndez C, Salas JA.

Mol Microbiol. 1998 Jun;28(6):1177-85.


Glycosylation of various flavonoids by recombinant oleandomycin glycosyltransferase from Streptomyces antibioticus in batch and repeated batch modes.

Choi SH, Ryu M, Yoon YJ, Kim DM, Lee EY.

Biotechnol Lett. 2012 Mar;34(3):499-505. doi: 10.1007/s10529-011-0789-z. Epub 2011 Nov 25.


Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors.

Zhou M, Hamza A, Zhan CG, Thorson JS.

J Nat Prod. 2013 Feb 22;76(2):279-86. doi: 10.1021/np300890h. Epub 2013 Jan 29.


Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions.

Gantt RW, Peltier-Pain P, Cournoyer WJ, Thorson JS.

Nat Chem Biol. 2011 Aug 21;7(10):685-91. doi: 10.1038/nchembio.638.


High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer.

Gantt RW, Thorson JS.

Methods Enzymol. 2012;516:345-60. doi: 10.1016/B978-0-12-394291-3.00009-5.


Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation.

Chang A, Singh S, Phillips GN Jr, Thorson JS.

Curr Opin Biotechnol. 2011 Dec;22(6):800-8. doi: 10.1016/j.copbio.2011.04.013. Epub 2011 May 16. Review.


Recombinant E. coli prototype strains for in vivo glycorandomization.

Williams GJ, Yang J, Zhang C, Thorson JS.

ACS Chem Biol. 2011 Jan 21;6(1):95-100. doi: 10.1021/cb100267k. Epub 2010 Oct 22.


Glycosyltransferase mechanisms: impact of a 5-fluoro substituent in acceptor and donor substrates on catalysis.

Hartman MC, Jiang S, Rush JS, Waechter CJ, Coward JK.

Biochemistry. 2007 Oct 16;46(41):11630-8. Epub 2007 Sep 21.


Probing the regiospecificity of enzyme-catalyzed steroid glycosylation.

Zhou M, Hou Y, Hamza A, Pain C, Zhan CG, Bugni TS, Thorson JS.

Org Lett. 2012 Nov 2;14(21):5424-7. doi: 10.1021/ol3024924. Epub 2012 Oct 18. Erratum in: Org Lett. 2012 Dec 21;14(24):6381. Pain, Christophe [added].


Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.

Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN Jr.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17649-54. doi: 10.1073/pnas.1108484108. Epub 2011 Oct 10.


The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses.

Hoffmeister D, Dräger G, Ichinose K, Rohr J, Bechthold A.

J Am Chem Soc. 2003 Apr 23;125(16):4678-9.


Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria.

Timmons SC, Thorson JS.

Curr Opin Chem Biol. 2008 Jun;12(3):297-305. doi: 10.1016/j.cbpa.2008.03.017. Epub 2008 Apr 18. Review.


Characterizing amosamine biosynthesis in amicetin reveals AmiG as a reversible retaining glycosyltransferase.

Chen R, Zhang H, Zhang G, Li S, Zhang G, Zhu Y, Liu J, Zhang C.

J Am Chem Soc. 2013 Aug 21;135(33):12152-5. doi: 10.1021/ja401016e. Epub 2013 Aug 9.

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