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Items: 1 to 20 of 108

1.

Identification of the bona fide DHDPS from a common plant pathogen.

Atkinson SC, Hor L, Dogovski C, Dobson RC, Perugini MA.

Proteins. 2014 Sep;82(9):1869-83. doi: 10.1002/prot.24539. Epub 2014 Jun 11.

PMID:
24677246
2.

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens.

Atkinson SC, Dogovski C, Dobson RC, Perugini MA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep 1;68(Pt 9):1040-7. doi: 10.1107/S1744309112033052. Epub 2012 Aug 30.

3.

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.

Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC.

Biochem J. 2008 Apr 15;411(2):351-60.

PMID:
18062777
4.

Structure of dihydrodipicolinate synthase from Methanocaldococcus jannaschii.

Padmanabhan B, Strange RW, Antonyuk SV, Ellis MJ, Hasnain SS, Iino H, Agari Y, Bessho Y, Yokoyama S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt 12):1222-6. doi: 10.1107/S174430910904651X. Epub 2009 Nov 27.

5.

Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.

Atkinson SC, Dogovski C, Downton MT, Pearce FG, Reboul CF, Buckle AM, Gerrard JA, Dobson RC, Wagner J, Perugini MA.

PLoS One. 2012;7(6):e38318. doi: 10.1371/journal.pone.0038318. Epub 2012 Jun 25.

6.

Crystal structure of dihydrodipicolinate synthase from Hahella chejuensis at 1.5 A resolution.

Kang BS, Kim YG, Ahn JW, Kim KJ.

Int J Biol Macromol. 2010 Jun;46(5):512-6. doi: 10.1016/j.ijbiomac.2010.03.005. Epub 2010 Mar 20.

PMID:
20227435
7.

Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.

Wolterink-van Loo S, Levisson M, Cabrières MC, Franssen MC, van der Oost J.

Extremophiles. 2008 May;12(3):461-9. doi: 10.1007/s00792-008-0152-z. Epub 2008 Mar 15.

PMID:
18340401
8.

From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae.

Dogovski C, Gorman MA, Ketaren NE, Praszkier J, Zammit LM, Mertens HD, Bryant G, Yang J, Griffin MD, Pearce FG, Gerrard JA, Jameson GB, Parker MW, Robins-Browne RM, Perugini MA.

PLoS One. 2013 Dec 13;8(12):e83419. doi: 10.1371/journal.pone.0083419. eCollection 2013.

10.

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

Domigan LJ, Scally SW, Fogg MJ, Hutton CA, Perugini MA, Dobson RC, Muscroft-Taylor AC, Gerrard JA, Devenish SR.

Biochim Biophys Acta. 2009 Oct;1794(10):1510-6. doi: 10.1016/j.bbapap.2009.06.020. Epub 2009 Jul 10.

PMID:
19595801
11.

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica.

Wubben JM, Dogovski C, Dobson RC, Codd R, Gerrard JA, Parker MW, Perugini MA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Nov 1;66(Pt 11):1511-6. doi: 10.1107/S1744309110036791. Epub 2010 Oct 29.

12.

Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen.

Burgess BR, Dobson RC, Bailey MF, Atkinson SC, Griffin MD, Jameson GB, Parker MW, Gerrard JA, Perugini MA.

J Biol Chem. 2008 Oct 10;283(41):27598-603. doi: 10.1074/jbc.M804231200. Epub 2008 Aug 5.

13.

How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?

Soares da Costa TP, Muscroft-Taylor AC, Dobson RC, Devenish SR, Jameson GB, Gerrard JA.

Biochimie. 2010 Jul;92(7):837-45. doi: 10.1016/j.biochi.2010.03.004. Epub 2010 Mar 29.

PMID:
20353808
14.

A dinucleotide mutation in dihydrodipicolinate synthase of Nicotiana sylvestris leads to lysine overproduction.

Ghislain M, Frankard V, Jacobs M.

Plant J. 1995 Nov;8(5):733-43. Erratum in: Plant J 1996 Jan;9(1):135.

PMID:
8528284
15.

Crystal structure and in silico studies of dihydrodipicolinate synthase (DHDPS) from Aquifex aeolicus.

Sridharan U, Ebihara A, Kuramitsu S, Yokoyama S, Kumarevel T, Ponnuraj K.

Extremophiles. 2014 Nov;18(6):973-85. doi: 10.1007/s00792-014-0667-4. Epub 2014 Jul 5.

PMID:
24996798
16.

Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.

Dobson RC, Griffin MD, Devenish SR, Pearce FG, Hutton CA, Gerrard JA, Jameson GB, Perugini MA.

Protein Sci. 2008 Dec;17(12):2080-90. doi: 10.1110/ps.037440.108. Epub 2008 Sep 11.

17.

Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax.

Voss JE, Scally SW, Taylor NL, Atkinson SC, Griffin MD, Hutton CA, Parker MW, Alderton MR, Gerrard JA, Dobson RC, Dogovski C, Perugini MA.

J Biol Chem. 2010 Feb 19;285(8):5188-95. doi: 10.1074/jbc.M109.038166. Epub 2009 Nov 30.

18.

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.

Atkinson SC, Dogovski C, Downton MT, Czabotar PE, Dobson RC, Gerrard JA, Wagner J, Perugini MA.

Plant Mol Biol. 2013 Mar;81(4-5):431-46. doi: 10.1007/s11103-013-0014-7. Epub 2013 Jan 26.

PMID:
23354837
19.

Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa.

Kaur N, Gautam A, Kumar S, Singh A, Singh N, Sharma S, Sharma R, Tewari R, Singh TP.

Int J Biol Macromol. 2011 Jun 1;48(5):779-87. doi: 10.1016/j.ijbiomac.2011.03.002. Epub 2011 Mar 10.

PMID:
21396954
20.

Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme.

Pearce FG, Dobson RC, Weber A, Lane LA, McCammon MG, Squire MA, Perugini MA, Jameson GB, Robinson CV, Gerrard JA.

Biochemistry. 2008 Nov 18;47(46):12108-17. doi: 10.1021/bi801094t. Epub 2008 Oct 21.

PMID:
18937497
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