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Items: 1 to 20 of 187

1.

Detection of an activated JAK3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis.

Kunze K, Gamerdinger U, Leßig-Owlanj J, Sorokina M, Brobeil A, Tur MK, Blau W, Burchardt A, Käbisch A, Schliesser G, Kiehl M, Rosenwald A, Rummel M, Grimminger F, Hain T, Chakraborty T, Bräuninger A, Gattenlöhner S.

Pathol Res Pract. 2014 Jun;210(6):369-76. doi: 10.1016/j.prp.2014.02.006. Epub 2014 Feb 23.

PMID:
24674452
2.

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH.

Nat Genet. 2009 Jul;41(7):838-42. doi: 10.1038/ng.391. Epub 2009 May 31.

PMID:
19483684
3.

A systematic modeling study on the pathogenic role of p38 MAPK activation in myelodysplastic syndromes.

Peng H, Wen J, Zhang L, Li H, Chang CC, Zu Y, Zhou X.

Mol Biosyst. 2012 Apr;8(4):1366-74. doi: 10.1039/c2mb05184b. Epub 2012 Feb 10.

PMID:
22327869
4.

[Myelodysplastic syndromes (MDS). Aspects of hematopathologic diagnosis].

Schmitt-Graeff A, Mattern D, Köhler H, Hezel J, Lübbert M.

Pathologe. 2000 Jan;21(1):1-15. Review. German.

PMID:
10663664
6.

Imbalance between apoptosis and telomerase activity in myelodysplastic syndromes: possible role in ineffective hemopoiesis.

Ohshima K, Karube K, Shimazaki K, Kamma H, Suzumiya J, Hamasaki M, Kikuchi M.

Leuk Lymphoma. 2003 Aug;44(8):1339-46.

PMID:
12952227
7.

Myelodysplastic syndromes: molecular pathogenesis and genomic changes.

Nolte F, Hofmann WK.

Ann Hematol. 2008 Oct;87(10):777-95. doi: 10.1007/s00277-008-0502-z. Epub 2008 May 31. Review.

PMID:
18516602
8.

Perspective on how to approach molecular diagnostics in acute myeloid leukemia and myelodysplastic syndromes in the era of next-generation sequencing.

Kohlmann A, Bacher U, Schnittger S, Haferlach T.

Leuk Lymphoma. 2014 Aug;55(8):1725-34. doi: 10.3109/10428194.2013.856427. Epub 2014 Feb 14. Review.

PMID:
24144312
9.

Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.

Puda A, Milosevic JD, Berg T, Klampfl T, Harutyunyan AS, Gisslinger B, Rumi E, Pietra D, Malcovati L, Elena C, Doubek M, Steurer M, Tosic N, Pavlovic S, Guglielmelli P, Pieri L, Vannucchi AM, Gisslinger H, Cazzola M, Kralovics R.

Am J Hematol. 2012 Mar;87(3):245-50. doi: 10.1002/ajh.22257. Epub 2011 Dec 21.

10.
11.

The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes.

Zhang L, Padron E, Lancet J.

Leuk Res. 2015 Jan;39(1):6-17. doi: 10.1016/j.leukres.2014.10.006. Epub 2014 Nov 6. Review.

PMID:
25465125
12.

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

Jiang Y, Dunbar A, Gondek LP, Mohan S, Rataul M, O'Keefe C, Sekeres M, Saunthararajah Y, Maciejewski JP.

Blood. 2009 Feb 5;113(6):1315-25. doi: 10.1182/blood-2008-06-163246. Epub 2008 Oct 2.

13.

Childhood myelodysplastic syndrome.

Chatterjee T, Choudhry VP.

Indian J Pediatr. 2013 Sep;80(9):764-71. doi: 10.1007/s12098-013-1130-8. Epub 2013 Aug 3. Review.

PMID:
23912822
14.

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.

Fernandez-Mercado M, Burns A, Pellagatti A, Giagounidis A, Germing U, Agirre X, Prosper F, Aul C, Killick S, Wainscoat JS, Schuh A, Boultwood J.

Haematologica. 2013 Dec;98(12):1856-64. doi: 10.3324/haematol.2013.086686. Epub 2013 Jul 5.

15.

Single nucleotide polymorphism array karyotyping: a diagnostic and prognostic tool in myelodysplastic syndromes with unsuccessful conventional cytogenetic testing.

Arenillas L, Mallo M, Ramos F, Guinta K, Barragán E, Lumbreras E, Larráyoz MJ, De Paz R, Tormo M, Abáigar M, Pedro C, Cervera J, Such E, José Calasanz M, Díez-Campelo M, Sanz GF, Hernández JM, Luño E, Saumell S, Maciejewski J, Florensa L, Solé F.

Genes Chromosomes Cancer. 2013 Dec;52(12):1167-77. doi: 10.1002/gcc.22112. Epub 2013 Oct 7.

PMID:
24123380
16.

Hematopoiesis-related microRNA expression in myelodysplastic syndromes.

Pons A, Nomdedeu B, Navarro A, Gaya A, Gel B, Diaz T, Valera S, Rozman M, Belkaid M, Montserrat E, Monzo M.

Leuk Lymphoma. 2009 Nov;50(11):1854-9. doi: 10.3109/10428190903147645.

PMID:
19883312
17.

Physician Education: Myelodysplastic Syndrome.

Yoshida Y.

Oncologist. 1996;1(4):284-287.

18.

Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview.

Jhanwar SC.

Adv Biol Regul. 2015 May;58:28-37. doi: 10.1016/j.jbior.2014.11.002. Epub 2014 Nov 20. Review.

PMID:
25499150
19.

Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations.

Lai JL, Preudhomme C, Zandecki M, Flactif M, Vanrumbeke M, Lepelley P, Wattel E, Fenaux P.

Leukemia. 1995 Mar;9(3):370-81.

PMID:
7885035
20.

[Comprehensive analysis of genomic detection for a patient with myelodysplastic syndrome].

Luo JX, Ai C, Huang YS, Wang HW, Hu CM, Zhao WW.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013 Dec;21(6):1501-6. doi: 10.7534/j.issn.1009-2137.2013.06.025. Chinese.

PMID:
24370037
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