Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 101

1.

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.

Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, Gygi SP, Lee TH, Lu KP, Toker A, Pandolfi PP, Asara JM, Kirschner MW, Sicinski P, Cantley L, Wei W.

Nature. 2014 Apr 24;508(7497):541-5. doi: 10.1038/nature13079. Epub 2014 Mar 9.

PMID:
24670654
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Phosphorylation of Akt at the C-terminal tail triggers Akt Activation.

Liu P, Wang Z, Wei W.

Cell Cycle. 2014 Jul 15;13(14):2162-4. doi: 10.4161/cc.29584. Epub 2014 Jun 16.

PMID:
24933731
[PubMed - in process]
3.

Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.

Lee SH, Lee MY, Han HJ.

Cell Prolif. 2008 Apr;41(2):230-47. doi: 10.1111/j.1365-2184.2008.00516.x.

PMID:
18336469
[PubMed - indexed for MEDLINE]
4.

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis.

Maddika S, Ande SR, Wiechec E, Hansen LL, Wesselborg S, Los M.

J Cell Sci. 2008 Apr 1;121(Pt 7):979-88. doi: 10.1242/jcs.009530.

PMID:
18354084
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.

Misra UK, Pizzo SV.

PLoS One. 2012;7(12):e51735. doi: 10.1371/journal.pone.0051735. Epub 2012 Dec 14.

PMID:
23272152
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.

Zhao X, Lu S, Nie J, Hu X, Luo W, Wu X, Liu H, Feng Q, Chang Z, Liu Y, Cao Y, Sun H, Li X, Hu Y, Yang Z.

Mol Cell Biol. 2014 Jun;34(11):1966-75. doi: 10.1128/MCB.00144-14. Epub 2014 Mar 24.

PMID:
24662050
[PubMed - indexed for MEDLINE]
7.

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.

El-Naggar S, Liu Y, Dean DC.

Mol Cell Biol. 2009 Nov;29(21):5710-7. doi: 10.1128/MCB.00197-09. Epub 2009 Aug 24.

PMID:
19703998
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.

Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.

Am J Physiol Cell Physiol. 2004 Aug;287(2):C281-91. Epub 2004 Mar 17.

PMID:
15028555
[PubMed - indexed for MEDLINE]
Free Article
9.

DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival.

Tu Y, Ji C, Yang B, Yang Z, Gu H, Lu CC, Wang R, Su ZL, Chen B, Sun WL, Xia JP, Bi ZG, He L.

Mol Cancer. 2013 Dec 24;12(1):172. doi: 10.1186/1476-4598-12-172.

PMID:
24365180
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt.

Hiraoka D, Okumura E, Kishimoto T.

Oncogene. 2011 Nov 3;30(44):4487-97. doi: 10.1038/onc.2011.155. Epub 2011 May 16.

PMID:
21577208
[PubMed - indexed for MEDLINE]
11.

Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.

Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ.

Cancer Res. 2006 Jul 1;66(13):6589-97.

PMID:
16818631
[PubMed - indexed for MEDLINE]
Free Article
12.

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT.

Mirza AM, Gysin S, Malek N, Nakayama K, Roberts JM, McMahon M.

Mol Cell Biol. 2004 Dec;24(24):10868-81.

PMID:
15572689
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

ERK1/2-dependent activation of mTOR/mTORC1/p70S6K regulates thrombin-induced RPE cell proliferation.

Parrales A, López E, Lee-Rivera I, López-Colomé AM.

Cell Signal. 2013 Apr;25(4):829-38. doi: 10.1016/j.cellsig.2012.12.023. Epub 2013 Jan 3.

PMID:
23291002
[PubMed - indexed for MEDLINE]
14.

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points.

Mateyak MK, Obaya AJ, Sedivy JM.

Mol Cell Biol. 1999 Jul;19(7):4672-83.

PMID:
10373516
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Involvement of Cx43 phosphorylation in 5'-N-ethylcarboxamide-induced migration and proliferation of mouse embryonic stem cells.

Kim MO, Lee YJ, Han HJ.

J Cell Physiol. 2010 Jul;224(1):187-94. doi: 10.1002/jcp.22117.

PMID:
20232318
[PubMed - indexed for MEDLINE]
16.

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.

Najafov A, Shpiro N, Alessi DR.

Biochem J. 2012 Dec 1;448(2):285-95. doi: 10.1042/BJ20121287.

PMID:
23030823
[PubMed - indexed for MEDLINE]
Free Article
17.

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W.

Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27.

PMID:
24161930
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

IKK interacts with rictor and regulates mTORC2.

Xu Y, Lai E, Liu J, Lin J, Yang C, Jia C, Li Y, Bai X, Li M.

Cell Signal. 2013 Nov;25(11):2239-45. doi: 10.1016/j.cellsig.2013.07.008. Epub 2013 Jul 17.

PMID:
23872070
[PubMed - indexed for MEDLINE]
19.

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.

Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.

Nat Med. 2002 Oct;8(10):1145-52. Epub 2002 Sep 16.

PMID:
12244301
[PubMed - indexed for MEDLINE]
20.

Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.

Misra UK, Pizzo SV.

J Cell Biochem. 2012 May;113(5):1488-500. doi: 10.1002/jcb.24018.

PMID:
22173835
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk