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Results: 1 to 20 of 98

1.

Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin.

Van Agthoven JF, Xiong JP, Alonso JL, Rui X, Adair BD, Goodman SL, Arnaout MA.

Nat Struct Mol Biol. 2014 Apr;21(4):383-8. doi: 10.1038/nsmb.2797. Epub 2014 Mar 23.

PMID:
24658351
[PubMed - indexed for MEDLINE]
2.

Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin.

Richards J, Miller M, Abend J, Koide A, Koide S, Dewhurst S.

J Mol Biol. 2003 Mar 7;326(5):1475-88.

PMID:
12595259
[PubMed - indexed for MEDLINE]
3.

Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin.

Adair BD, Xiong JP, Maddock C, Goodman SL, Arnaout MA, Yeager M.

J Cell Biol. 2005 Mar 28;168(7):1109-18.

PMID:
15795319
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin.

Spitaleri A, Mari S, Curnis F, Traversari C, Longhi R, Bordignon C, Corti A, Rizzardi GP, Musco G.

J Biol Chem. 2008 Jul 11;283(28):19757-68. doi: 10.1074/jbc.M710273200. Epub 2008 May 13.

PMID:
18480047
[PubMed - indexed for MEDLINE]
Free Article
5.

How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation.

Puklin-Faucher E, Gao M, Schulten K, Vogel V.

J Cell Biol. 2006 Oct 23;175(2):349-60.

PMID:
17060501
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin.

Le Trong I, McDevitt TC, Nelson KE, Stayton PS, Stenkamp RE.

Acta Crystallogr D Biol Crystallogr. 2003 May;59(Pt 5):828-34. Epub 2003 Apr 25.

PMID:
12777798
[PubMed - indexed for MEDLINE]
7.

Interdomain tilt angle determines integrin-dependent function of the ninth and tenth FIII domains of human fibronectin.

Altroff H, Schlinkert R, van der Walle CF, Bernini A, Campbell ID, Werner JM, Mardon HJ.

J Biol Chem. 2004 Dec 31;279(53):55995-6003. Epub 2004 Oct 12.

PMID:
15485890
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.

Fujii Y, Okuda D, Fujimoto Z, Horii K, Morita T, Mizuno H.

J Mol Biol. 2003 Oct 3;332(5):1115-22.

PMID:
14499613
[PubMed - indexed for MEDLINE]
9.

De novo expression of the integrin alpha5beta1 regulates alphavbeta3-mediated adhesion and migration on fibrinogen.

Ly DP, Zazzali KM, Corbett SA.

J Biol Chem. 2003 Jun 13;278(24):21878-85. Epub 2003 Apr 3.

PMID:
12676956
[PubMed - indexed for MEDLINE]
Free Article
10.

Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch.

Krammer A, Lu H, Isralewitz B, Schulten K, Vogel V.

Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1351-6.

PMID:
9990027
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

Danen EH, Sonneveld P, Brakebusch C, Fassler R, Sonnenberg A.

J Cell Biol. 2002 Dec 23;159(6):1071-86. Epub 2002 Dec 16.

PMID:
12486108
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Synthetic RGD-containing alpha-helical coiled coil peptides promote integrin-dependent cell adhesion.

Villard V, Kalyuzhniy O, Riccio O, Potekhin S, Melnik TN, Kajava AV, Rüegg C, Corradin G.

J Pept Sci. 2006 Mar;12(3):206-12.

PMID:
16103993
[PubMed - indexed for MEDLINE]
14.

Analysis of the interaction between RGD-expressing adenovirus type 5 fiber knob domains and alphavbeta3 integrin reveals distinct binding profiles and intracellular trafficking.

Lord R, Parsons M, Kirby I, Beavil A, Hunt J, Sutton B, Santis G.

J Gen Virol. 2006 Sep;87(Pt 9):2497-505.

PMID:
16894187
[PubMed - indexed for MEDLINE]
Free Article
15.

Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.

Burrows L, Clark K, Mould AP, Humphries MJ.

Biochem J. 1999 Dec 1;344 Pt 2:527-33.

PMID:
10567237
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutagenesis studies of the β I domain metal ion binding sites on integrin αVβ3 ligand binding affinity.

Raborn J, Luo BH.

J Cell Biochem. 2012 Apr;113(4):1190-7. doi: 10.1002/jcb.23448.

PMID:
22095620
[PubMed - indexed for MEDLINE]
17.

Selective interaction of a conformationally-constrained Arg-Gly-Asp (RGD) motif with the integrin receptor alphavbeta3 expressed on human tumor cells.

Lanza P, Felding-Habermann B, Ruggeri ZM, Zanetti M, Billetta R.

Blood Cells Mol Dis. 1997 Aug;23(2):230-41.

PMID:
9268674
[PubMed - indexed for MEDLINE]
18.

Accessibility to the fibronectin synergy site in a 3D matrix regulates engagement of alpha5beta1 versus alphavbeta3 integrin receptors.

Mao Y, Schwarzbauer JE.

Cell Commun Adhes. 2006 Sep-Dec;13(5-6):267-77.

PMID:
17162669
[PubMed - indexed for MEDLINE]
19.

Mapping of heparin/heparan sulfate binding sites on αvβ3 integrin by molecular docking.

Ballut L, Sapay N, Chautard E, Imberty A, Ricard-Blum S.

J Mol Recognit. 2013 Feb;26(2):76-85. doi: 10.1002/jmr.2250.

PMID:
23334915
[PubMed - indexed for MEDLINE]
20.

The eighth FIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth FIII domain.

Altroff H, van der Walle CF, Asselin J, Fairless R, Campbell ID, Mardon HJ.

J Biol Chem. 2001 Oct 19;276(42):38885-92. Epub 2001 Aug 10.

PMID:
11500513
[PubMed - indexed for MEDLINE]
Free Article

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