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Results: 1 to 20 of 101

1.

Proteomic analysis implicates translationally controlled tumor protein as a novel mediator of occlusive vascular remodeling in pulmonary arterial hypertension.

Lavoie JR, Ormiston ML, Perez-Iratxeta C, Courtman DW, Jiang B, Ferrer E, Caruso P, Southwood M, Foster WS, Morrell NW, Stewart DJ.

Circulation. 2014 May 27;129(21):2125-35. doi: 10.1161/CIRCULATIONAHA.114.008777. Epub 2014 Mar 21.

PMID:
24657995
[PubMed - in process]
2.

Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8.

Drake KM, Zygmunt D, Mavrakis L, Harbor P, Wang L, Comhair SA, Erzurum SC, Aldred MA.

Am J Respir Crit Care Med. 2011 Dec 15;184(12):1400-8. doi: 10.1164/rccm.201106-1130OC. Epub 2011 Sep 15.

PMID:
21920918
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension.

Li M, Vattulainen S, Aho J, Orcholski M, Rojas V, Yuan K, Helenius M, Taimen P, Myllykangas S, De Jesus Perez V, Koskenvuo JW, Alastalo TP.

Am J Respir Cell Mol Biol. 2014 Jun;50(6):1118-28. doi: 10.1165/rcmb.2013-0349OC.

PMID:
24433082
[PubMed - in process]
4.

Role of apoptosis in pulmonary hypertension: from experimental models to clinical trials.

Jurasz P, Courtman D, Babaie S, Stewart DJ.

Pharmacol Ther. 2010 Apr;126(1):1-8. doi: 10.1016/j.pharmthera.2009.12.006. Epub 2010 Feb 1. Review.

PMID:
20117135
[PubMed - indexed for MEDLINE]
5.

Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension.

Toshner M, Voswinckel R, Southwood M, Al-Lamki R, Howard LS, Marchesan D, Yang J, Suntharalingam J, Soon E, Exley A, Stewart S, Hecker M, Zhu Z, Gehling U, Seeger W, Pepke-Zaba J, Morrell NW.

Am J Respir Crit Care Med. 2009 Oct 15;180(8):780-7. doi: 10.1164/rccm.200810-1662OC. Epub 2009 Jul 23.

PMID:
19628780
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Heritable Pulmonary Arterial Hypertension.

Loyd JE, Phillips JA.

In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.
2002 Jul 18 [updated 2012 Dec 20].

PMID:
20301658
[PubMed]
Books & Documents
7.

Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension.

Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA, Karoubi G, Courtman DW, Zucco L, Granton J, Stewart DJ.

Circ Res. 2006 Feb 3;98(2):209-17. Epub 2005 Dec 15.

PMID:
16357305
[PubMed - indexed for MEDLINE]
Free Article
8.

Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.

Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay É, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S.

J Am Heart Assoc. 2013 Jan 16;2(1):e005157. doi: 10.1161/JAHA.112.005157.

PMID:
23525442
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.

Talati M, West J, Blackwell TR, Loyd JE, Meyrick B.

Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L363-73. doi: 10.1152/ajplung.00295.2009. Epub 2010 Jun 18.

PMID:
20562228
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension.

Drake KM, Dunmore BJ, McNelly LN, Morrell NW, Aldred MA.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):403-9. doi: 10.1165/rcmb.2013-0100OC.

PMID:
23590310
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Proteomic analysis identifies translationally controlled tumor protein as a mediator of phosphatase of regenerating liver-3-promoted proliferation, migration and invasion in human colon cancer cells.

Chu ZH, Liu L, Zheng CX, Lai W, Li SF, Wu H, Zeng YJ, Zhao HY, Guan YF.

Chin Med J (Engl). 2011 Nov;124(22):3778-85.

PMID:
22340241
[PubMed - indexed for MEDLINE]
Free Article
12.

Genetics and genomics of pulmonary arterial hypertension.

Soubrier F, Chung WK, Machado R, Grünig E, Aldred M, Geraci M, Loyd JE, Elliott CG, Trembath RC, Newman JH, Humbert M.

J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D13-21. doi: 10.1016/j.jacc.2013.10.035. Review.

PMID:
24355637
[PubMed - indexed for MEDLINE]
13.

Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension.

Tu L, Dewachter L, Gore B, Fadel E, Dartevelle P, Simonneau G, Humbert M, Eddahibi S, Guignabert C.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):311-22. doi: 10.1165/rcmb.2010-0317OC. Epub 2010 Oct 29.

PMID:
21037114
[PubMed - indexed for MEDLINE]
14.

Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations.

Pfarr N, Szamalek-Hoegel J, Fischer C, Hinderhofer K, Nagel C, Ehlken N, Tiede H, Olschewski H, Reichenberger F, Ghofrani AH, Seeger W, Grünig E.

Respir Res. 2011 Jul 29;12:99. doi: 10.1186/1465-9921-12-99.

PMID:
21801371
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Proteomic analysis of lung tissues from patients with pulmonary arterial hypertension.

Abdul-Salam VB, Wharton J, Cupitt J, Berryman M, Edwards RJ, Wilkins MR.

Circulation. 2010 Nov 16;122(20):2058-67. doi: 10.1161/CIRCULATIONAHA.110.972745. Epub 2010 Nov 1.

PMID:
21041689
[PubMed - indexed for MEDLINE]
Free Article
16.

A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension.

Patel M, Predescu D, Tandon R, Bardita C, Pogoriler J, Bhorade S, Wang M, Comhair S, Hemnes AR, Chen J, Machado R, Husain A, Erzurum S, Predescu S.

J Biol Chem. 2013 Sep 6;288(36):25701-16. doi: 10.1074/jbc.M113.502674. Epub 2013 Jul 26. Erratum in: J Biol Chem. 2013 Dec 27;288(52):36855. Ryan-Hemnes, Anna [corrected to Hemnes, Anna Ryan].

PMID:
23893408
[PubMed - indexed for MEDLINE]
17.

Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

Hong KH, Lee YJ, Lee E, Park SO, Han C, Beppu H, Li E, Raizada MK, Bloch KD, Oh SP.

Circulation. 2008 Aug 12;118(7):722-30. doi: 10.1161/CIRCULATIONAHA.107.736801. Epub 2008 Jul 28.

PMID:
18663089
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.

West J, Austin E, Fessel JP, Loyd J, Hamid R.

Drug Discov Today. 2014 May 2. pii: S1359-6446(14)00152-4. doi: 10.1016/j.drudis.2014.04.015. [Epub ahead of print] Review.

PMID:
24794464
[PubMed - as supplied by publisher]
19.

A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples.

Caruso P, Dempsie Y, Stevens HC, McDonald RA, Long L, Lu R, White K, Mair KM, McClure JD, Southwood M, Upton P, Xin M, van Rooij E, Olson EN, Morrell NW, MacLean MR, Baker AH.

Circ Res. 2012 Jul 20;111(3):290-300. doi: 10.1161/CIRCRESAHA.112.267591. Epub 2012 Jun 19.

PMID:
22715469
[PubMed - indexed for MEDLINE]
Free Article
20.

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.

Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, Bernstein D, Solow-Cordero DE, Beachy PA, Wandless TJ, Ten Dijke P, Rabinovitch M.

J Clin Invest. 2013 Aug 1;123(8):3600-13. doi: 10.1172/JCI65592. Epub 2013 Jul 15.

PMID:
23867624
[PubMed - indexed for MEDLINE]
Free PMC Article

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