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Items: 1 to 20 of 109

1.

Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells.

Cunnusamy K, Baughman EJ, Franco J, Ortega SB, Sinha S, Chaudhary P, Greenberg BM, Frohman EM, Karandikar NJ.

Clin Immunol. 2014 May-Jun;152(1-2):115-26. doi: 10.1016/j.clim.2014.03.005. Epub 2014 Mar 20.

2.

Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis.

Baughman EJ, Mendoza JP, Ortega SB, Ayers CL, Greenberg BM, Frohman EM, Karandikar NJ.

J Autoimmun. 2011 Mar;36(2):115-24. doi: 10.1016/j.jaut.2010.12.003. Epub 2011 Jan 22.

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Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma.

Mortarini R, Piris A, Maurichi A, Molla A, Bersani I, Bono A, Bartoli C, Santinami M, Lombardo C, Ravagnani F, Cascinelli N, Parmiani G, Anichini A.

Cancer Res. 2003 May 15;63(10):2535-45.

6.

Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function.

Filaci G, Fravega M, Negrini S, Procopio F, Fenoglio D, Rizzi M, Brenci S, Contini P, Olive D, Ghio M, Setti M, Accolla RS, Puppo F, Indiveri F.

Hum Immunol. 2004 Feb;65(2):142-56.

PMID:
14969769
7.

Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27.

Morishima N, Owaki T, Asakawa M, Kamiya S, Mizuguchi J, Yoshimoto T.

J Immunol. 2005 Aug 1;175(3):1686-93.

8.

New regulatory CD19(+)CD25(+) B-cell subset in clinically isolated syndrome and multiple sclerosis relapse. Changes after glucocorticoids.

de Andrés C, Tejera-Alhambra M, Alonso B, Valor L, Teijeiro R, Ramos-Medina R, Mateos D, Faure F, Sánchez-Ramón S.

J Neuroimmunol. 2014 May 15;270(1-2):37-44. doi: 10.1016/j.jneuroim.2014.02.003. Epub 2014 Feb 14.

PMID:
24662004
9.

Expansion of regulatory CD8+ T-lymphocytes and fall of activated CD8+ T-lymphocytes after i.v. methyl-prednisolone for multiple sclerosis relapse.

Aristimuño C, Navarro J, de Andrés C, Martínez-Ginés L, Giménez-Roldán S, Fernández-Cruz E, Sánchez-Ramón S.

J Neuroimmunol. 2008 Nov 15;204(1-2):131-5. doi: 10.1016/j.jneuroim.2008.08.009.

PMID:
18835045
10.

CD8+HLA-DR+ T lymphocytes are increased in common variable immunodeficiency patients with impaired memory B-cell differentiation.

Viallard JF, Blanco P, André M, Etienne G, Liferman F, Neau D, Vidal E, Moreau JF, Pellegrin JL.

Clin Immunol. 2006 Apr;119(1):51-8. Epub 2006 Jan 18.

PMID:
16413828
11.

Dysfunction of IL-10-producing type 1 regulatory T cells and CD4(+)CD25(+) regulatory T cells in a mimic model of human multiple sclerosis in Cynomolgus monkeys.

Ma A, Xiong Z, Hu Y, Qi S, Song L, Dun H, Zhang L, Lou D, Yang P, Zhao Z, Wang X, Zhang D, Daloze P, Chen H.

Int Immunopharmacol. 2009 May;9(5):599-608. doi: 10.1016/j.intimp.2009.01.034. Epub 2009 Feb 10.

PMID:
19539557
12.

Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response.

Lowther DE, Chong DL, Ascough S, Ettorre A, Ingram RJ, Boyton RJ, Altmann DM.

Acta Neuropathol. 2013 Oct;126(4):501-15. doi: 10.1007/s00401-013-1159-9. Epub 2013 Aug 10.

PMID:
23934116
13.

Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis.

Abrahamsson SV, Angelini DF, Dubinsky AN, Morel E, Oh U, Jones JL, Carassiti D, Reynolds R, Salvetti M, Calabresi PA, Coles AJ, Battistini L, Martin R, Burt RK, Muraro PA.

Brain. 2013 Sep;136(Pt 9):2888-903. doi: 10.1093/brain/awt182. Epub 2013 Jul 17.

14.

Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replication.

Pallikkuth S, Rogers K, Villinger F, Dosterii M, Vaccari M, Franchini G, Pahwa R, Pahwa S.

Vaccine. 2011 Nov 15;29(49):9229-38. doi: 10.1016/j.vaccine.2011.09.118. Epub 2011 Oct 11.

15.

Immune regulation of multiple sclerosis by CD8+ T cells.

Sinha S, Itani FR, Karandikar NJ.

Immunol Res. 2014 Aug;59(1-3):254-65. doi: 10.1007/s12026-014-8529-9. Review.

16.

Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus.

Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF.

Arthritis Rheum. 2005 Jan;52(1):201-11.

17.

Granzyme B regulates antiviral CD8+ T cell responses.

Salti SM, Hammelev EM, Grewal JL, Reddy ST, Zemple SJ, Grossman WJ, Grayson MH, Verbsky JW.

J Immunol. 2011 Dec 15;187(12):6301-9. doi: 10.4049/jimmunol.1100891. Epub 2011 Nov 14.

18.

Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis.

Tennakoon DK, Mehta RS, Ortega SB, Bhoj V, Racke MK, Karandikar NJ.

J Immunol. 2006 Jun 1;176(11):7119-29.

19.

Human decidual tissue contains differentiated CD8+ effector-memory T cells with unique properties.

Tilburgs T, Schonkeren D, Eikmans M, Nagtzaam NM, Datema G, Swings GM, Prins F, van Lith JM, van der Mast BJ, Roelen DL, Scherjon SA, Claas FH.

J Immunol. 2010 Oct 1;185(7):4470-7. doi: 10.4049/jimmunol.0903597. Epub 2010 Sep 3.

20.

Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation.

Mahic M, Henjum K, Yaqub S, Bjørnbeth BA, Torgersen KM, Taskén K, Aandahl EM.

Eur J Immunol. 2008 Mar;38(3):640-6. doi: 10.1002/eji.200737529.

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