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Scale-free functional connectivity of the brain is maintained in anesthetized healthy participants but not in patients with unresponsive wakefulness syndrome.

Liu X, Ward BD, Binder JR, Li SJ, Hudetz AG.

PLoS One. 2014 Mar 19;9(3):e92182. doi: 10.1371/journal.pone.0092182. eCollection 2014.


How are different neural networks related to consciousness?

Qin P, Wu X, Huang Z, Duncan NW, Tang W, Wolff A, Hu J, Gao L, Jin Y, Wu X, Zhang J, Lu L, Wu C, Qu X, Mao Y, Weng X, Zhang J, Northoff G.

Ann Neurol. 2015 Oct;78(4):594-605. doi: 10.1002/ana.24479. Epub 2015 Aug 20.


Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness.

Boveroux P, Vanhaudenhuyse A, Bruno MA, Noirhomme Q, Lauwick S, Luxen A, Degueldre C, Plenevaux A, Schnakers C, Phillips C, Brichant JF, Bonhomme V, Maquet P, Greicius MD, Laureys S, Boly M.

Anesthesiology. 2010 Nov;113(5):1038-53. doi: 10.1097/ALN.0b013e3181f697f5.


Brain networks maintain a scale-free organization across consciousness, anesthesia, and recovery: evidence for adaptive reconfiguration.

Lee U, Oh G, Kim S, Noh G, Choi B, Mashour GA.

Anesthesiology. 2010 Nov;113(5):1081-91. doi: 10.1097/ALN.0b013e3181f229b5.


Multiple fMRI system-level baseline connectivity is disrupted in patients with consciousness alterations.

Demertzi A, Gómez F, Crone JS, Vanhaudenhuyse A, Tshibanda L, Noirhomme Q, Thonnard M, Charland-Verville V, Kirsch M, Laureys S, Soddu A.

Cortex. 2014 Mar;52:35-46. doi: 10.1016/j.cortex.2013.11.005. Epub 2013 Nov 20.


Spatiotemporal reconfiguration of large-scale brain functional networks during propofol-induced loss of consciousness.

Schröter MS, Spoormaker VI, Schorer A, Wohlschläger A, Czisch M, Kochs EF, Zimmer C, Hemmer B, Schneider G, Jordan D, Ilg R.

J Neurosci. 2012 Sep 12;32(37):12832-40. doi: 10.1523/JNEUROSCI.6046-11.2012.


Brain functional integration decreases during propofol-induced loss of consciousness.

Schrouff J, Perlbarg V, Boly M, Marrelec G, Boveroux P, Vanhaudenhuyse A, Bruno MA, Laureys S, Phillips C, Pélégrini-Issac M, Maquet P, Benali H.

Neuroimage. 2011 Jul 1;57(1):198-205. doi: 10.1016/j.neuroimage.2011.04.020. Epub 2011 Apr 16.


Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients.

Demertzi A, Antonopoulos G, Heine L, Voss HU, Crone JS, de Los Angeles C, Bahri MA, Di Perri C, Vanhaudenhuyse A, Charland-Verville V, Kronbichler M, Trinka E, Phillips C, Gomez F, Tshibanda L, Soddu A, Schiff ND, Whitfield-Gabrieli S, Laureys S.

Brain. 2015 Sep;138(Pt 9):2619-31. doi: 10.1093/brain/awv169. Epub 2015 Jun 27.


Differential effects of deep sedation with propofol on the specific and nonspecific thalamocortical systems: a functional magnetic resonance imaging study.

Liu X, Lauer KK, Ward BD, Li SJ, Hudetz AG.

Anesthesiology. 2013 Jan;118(1):59-69. doi: 10.1097/ALN.0b013e318277a801.


Reconfiguration of network hub structure after propofol-induced unconsciousness.

Lee H, Mashour GA, Noh GJ, Kim S, Lee U.

Anesthesiology. 2013 Dec;119(6):1347-59. doi: 10.1097/ALN.0b013e3182a8ec8c.


Posterior cingulate cortex-related co-activation patterns: a resting state FMRI study in propofol-induced loss of consciousness.

Amico E, Gomez F, Di Perri C, Vanhaudenhuyse A, Lesenfants D, Boveroux P, Bonhomme V, Brichant JF, Marinazzo D, Laureys S.

PLoS One. 2014 Jun 30;9(6):e100012. doi: 10.1371/journal.pone.0100012. eCollection 2014.


Can transcranial direct current stimulation be useful in differentiating unresponsive wakefulness syndrome from minimally conscious state patients?

Naro A, Calabrò RS, Russo M, Leo A, Pollicino P, Quartarone A, Bramanti P.

Restor Neurol Neurosci. 2015;33(2):159-76. doi: 10.3233/RNN-140448.


Functional neuroanatomy of disorders of consciousness.

Di Perri C, Stender J, Laureys S, Gosseries O.

Epilepsy Behav. 2014 Jan;30:28-32. doi: 10.1016/j.yebeh.2013.09.014. Epub 2013 Oct 5. Review. Erratum in: Epilepsy Behav. 2014 Jul;36:153.


Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study.

Di Perri C, Bahri MA, Amico E, Thibaut A, Heine L, Antonopoulos G, Charland-Verville V, Wannez S, Gomez F, Hustinx R, Tshibanda L, Demertzi A, Soddu A, Laureys S.

Lancet Neurol. 2016 Apr 27. pii: S1474-4422(16)00111-3. doi: 10.1016/S1474-4422(16)00111-3. [Epub ahead of print]


Dynamic change of global and local information processing in propofol-induced loss and recovery of consciousness.

Monti MM, Lutkenhoff ES, Rubinov M, Boveroux P, Vanhaudenhuyse A, Gosseries O, Bruno MA, Noirhomme Q, Boly M, Laureys S.

PLoS Comput Biol. 2013;9(10):e1003271. doi: 10.1371/journal.pcbi.1003271. Epub 2013 Oct 17.


Quantitative rates of brain glucose metabolism distinguish minimally conscious from vegetative state patients.

Stender J, Kupers R, Rodell A, Thibaut A, Chatelle C, Bruno MA, Gejl M, Bernard C, Hustinx R, Laureys S, Gjedde A.

J Cereb Blood Flow Metab. 2015 Jan;35(1):58-65. doi: 10.1038/jcbfm.2014.169. Epub 2014 Oct 8.


Large-scale brain functional modularity is reflected in slow electroencephalographic rhythms across the human non-rapid eye movement sleep cycle.

Tagliazucchi E, von Wegner F, Morzelewski A, Brodbeck V, Borisov S, Jahnke K, Laufs H.

Neuroimage. 2013 Apr 15;70:327-39. doi: 10.1016/j.neuroimage.2012.12.073. Epub 2013 Jan 9.


Emerging from an unresponsive wakefulness syndrome: brain plasticity has to cross a threshold level.

Bagnato S, Boccagni C, Sant'angelo A, Fingelkurts AA, Fingelkurts AA, Galardi G.

Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 2):2721-36. doi: 10.1016/j.neubiorev.2013.09.007. Epub 2013 Sep 20. Review.


The directionality and functional organization of frontoparietal connectivity during consciousness and anesthesia in humans.

Lee U, Kim S, Noh GJ, Choi BM, Hwang E, Mashour GA.

Conscious Cogn. 2009 Dec;18(4):1069-78. doi: 10.1016/j.concog.2009.04.004. Epub 2009 May 13.


The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation.

Gili T, Saxena N, Diukova A, Murphy K, Hall JE, Wise RG.

J Neurosci. 2013 Feb 27;33(9):4024-31. doi: 10.1523/JNEUROSCI.3480-12.2013.

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