Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 110

1.

Pharmacological inhibition of TPL2/MAP3K8 blocks human cytotoxic T lymphocyte effector functions.

Chowdhury FZ, Estrada LD, Murray S, Forman J, Farrar JD.

PLoS One. 2014 Mar 18;9(3):e92187. doi: 10.1371/journal.pone.0092187. eCollection 2014.

PMID:
24642963
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production.

Mielke LA, Elkins KL, Wei L, Starr R, Tsichlis PN, O'Shea JJ, Watford WT.

J Immunol. 2009 Dec 15;183(12):7984-93. doi: 10.4049/jimmunol.0901336. Epub .

PMID:
19933865
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.

Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, Jankovic D, Tsichlis PN, O'Shea JJ.

J Exp Med. 2008 Nov 24;205(12):2803-12. doi: 10.1084/jem.20081461. Epub 2008 Nov 10.

PMID:
19001140
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

TPL2 kinase regulates the inflammatory milieu of the myeloma niche.

Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F.

Blood. 2014 May 22;123(21):3305-15. doi: 10.1182/blood-2014-02-554071. Epub 2014 Apr 10.

PMID:
24723682
[PubMed - indexed for MEDLINE]
5.

Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen.

Berg RE, Crossley E, Murray S, Forman J.

J Exp Med. 2003 Nov 17;198(10):1583-93.

PMID:
14623912
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice.

Watford WT, Wang CC, Tsatsanis C, Mielke LA, Eliopoulos AG, Daskalakis C, Charles N, Odom S, Rivera J, O'Shea J, Tsichlis PN.

J Immunol. 2010 Jan 1;184(1):105-13. doi: 10.4049/jimmunol.0803730. Epub 2009 Dec 2.

PMID:
19955521
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.

Jager J, Grémeaux T, Gonzalez T, Bonnafous S, Debard C, Laville M, Vidal H, Tran A, Gual P, Le Marchand-Brustel Y, Cormont M, Tanti JF.

Diabetes. 2010 Jan;59(1):61-70. doi: 10.2337/db09-0470. Epub 2009 Oct 6.

PMID:
19808894
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency.

Umeshappa CS, Nanjundappa RH, Xie Y, Freywald A, Xu Q, Xiang J.

Immunology. 2013 Apr;138(4):298-306. doi: 10.1111/imm.12033.

PMID:
23113741
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production.

McNab FW, Ewbank J, Rajsbaum R, Stavropoulos E, Martirosyan A, Redford PS, Wu X, Graham CM, Saraiva M, Tsichlis P, Chaussabel D, Ley SC, O'Garra A.

J Immunol. 2013 Aug 15;191(4):1732-43. doi: 10.4049/jimmunol.1300146. Epub 2013 Jul 10.

PMID:
23842752
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells.

Raczkowski F, Ritter J, Heesch K, Schumacher V, Guralnik A, Höcker L, Raifer H, Klein M, Bopp T, Harb H, Kesper DA, Pfefferle PI, Grusdat M, Lang PA, Mittrücker HW, Huber M.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15019-24. doi: 10.1073/pnas.1309378110. Epub 2013 Aug 26.

PMID:
23980171
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.

Sugimoto K, Ohata M, Miyoshi J, Ishizaki H, Tsuboi N, Masuda A, Yoshikai Y, Takamoto M, Sugane K, Matsuo S, Shimada Y, Matsuguchi T.

J Clin Invest. 2004 Sep;114(6):857-66.

PMID:
15372110
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammation.

Rowley SM, Kuriakose T, Dockery LM, Tran-Ngyuen T, Gingerich AD, Wei L, Watford WT.

J Biol Chem. 2014 May 30;289(22):15788-97. doi: 10.1074/jbc.M114.559344. Epub 2014 Apr 8.

PMID:
24713702
[PubMed - indexed for MEDLINE]
14.

MyD88 and interferon-alpha/beta are differentially required for dendritic cell maturation but dispensable for development of protective memory against Listeria.

Tam MA, Wick MJ.

Immunology. 2009 Nov;128(3):429-38. doi: 10.1111/j.1365-2567.2009.03128.x.

PMID:
20067542
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cot/Tpl2 regulates IL-23 p19 expression in LPS-stimulated macrophages through ERK activation.

Kakimoto K, Musikacharoen T, Chiba N, Bandow K, Ohnishi T, Matsuguchi T.

J Physiol Biochem. 2010 Mar;66(1):47-53. doi: 10.1007/s13105-010-0007-9. Epub 2010 Apr 20.

PMID:
20405269
[PubMed - indexed for MEDLINE]
16.

Rapid generation of potent and tumor-specific cytotoxic T lymphocytes by interleukin 18 using dendritic cells and natural killer cells.

Tanaka F, Hashimoto W, Okamura H, Robbins PD, Lotze MT, Tahara H.

Cancer Res. 2000 Sep 1;60(17):4838-44.

PMID:
10987295
[PubMed - indexed for MEDLINE]
Free Article
17.

Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses.

Wang Y, Da'Dara AA, Thomas PG, Harn DA.

Immunology. 2010 Mar;129(3):406-17. doi: 10.1111/j.1365-2567.2009.03193.x. Epub 2009 Nov 16.

PMID:
19922421
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production.

Neighbors M, Xu X, Barrat FJ, Ruuls SR, Churakova T, Debets R, Bazan JF, Kastelein RA, Abrams JS, O'Garra A.

J Exp Med. 2001 Aug 6;194(3):343-54.

PMID:
11489953
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model.

Henry CJ, Grayson JM, Brzoza-Lewis KL, Mitchell LM, Westcott MM, Cook AS, Hiltbold EM.

Cell Immunol. 2010;264(1):23-31. doi: 10.1016/j.cellimm.2010.04.007. Epub 2010 Apr 24.

PMID:
20483409
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.

Cui W, Joshi NS, Jiang A, Kaech SM.

Vaccine. 2009 Mar 26;27(15):2177-87. doi: 10.1016/j.vaccine.2009.01.088. Epub 2009 Feb 6.

PMID:
19201385
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk