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Filaggrin loss-of-function mutations and incident cancer: a population-based study.

Skaaby T, Husemoen LL, Thyssen JP, Meldgaard M, Thuesen BH, Pisinger C, Jørgensen T, Carlsen K, Johansen JD, Menné T, Szecsi PB, Stender S, Linneberg A.

Br J Dermatol. 2014 Dec;171(6):1407-14. doi: 10.1111/bjd.12969. Epub 2014 Nov 9.


Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults.

Skaaby T, Husemoen LL, Jørgensen T, Johansen JD, Menné T, Szecsi PB, Stender S, Bager P, Thyssen JP, Linneberg A.

PLoS One. 2014 Jun 6;9(6):e99437. doi: 10.1371/journal.pone.0099437. eCollection 2014.


No association between loss-of-function mutations in filaggrin and diabetes, cardiovascular disease, and all-cause mortality.

Husemoen LL, Skaaby T, Jørgensen T, Thyssen JP, Meldgaard M, Szecsi PB, Stender S, Johansen JD, Linneberg A.

PLoS One. 2013 Dec 18;8(12):e84293. doi: 10.1371/journal.pone.0084293. eCollection 2013.


Prospective population-based study of the association between serum 25-hydroxyvitamin-D levels and the incidence of specific types of cancer.

Skaaby T, Husemoen LL, Thuesen BH, Pisinger C, Jørgensen T, Roswall N, Larsen SC, Linneberg A.

Cancer Epidemiol Biomarkers Prev. 2014 Jul;23(7):1220-9. doi: 10.1158/1055-9965.EPI-14-0007. Epub 2014 Apr 30.


Carriers of filaggrin gene (FLG) mutations avoid professional exposure to irritants in adulthood.

Bandier J, Ross-Hansen K, Carlsen BC, Menné T, Linneberg A, Stender S, Szecsi PB, Meldgaard M, Thyssen JP, Johansen JD.

Contact Dermatitis. 2013 Dec;69(6):355-62. doi: 10.1111/cod.12097. Epub 2013 Jun 28.


Common filaggrin gene mutations and risk of cervical cancer.

Bager P, Wohlfahrt J, Sørensen E, Ullum H, Høgdall CK, Palle C, Husemoen LL, Linneberg A, Kjaer SK, Melbye M, Thyssen JP.

Acta Oncol. 2015 Feb;54(2):217-23. doi: 10.3109/0284186X.2014.973613. Epub 2014 Nov 10.


Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure.

Bisgaard H, Simpson A, Palmer CN, Bønnelykke K, McLean I, Mukhopadhyay S, Pipper CB, Halkjaer LB, Lipworth B, Hankinson J, Woodcock A, Custovic A.

PLoS Med. 2008 Jun 24;5(6):e131. doi: 10.1371/journal.pmed.0050131.


Association between loss-of-function mutations in the filaggrin gene and self-reported food allergy and alcohol sensitivity.

Linneberg A, Fenger RV, Husemoen LL, Thuesen BH, Skaaby T, Gonzalez-Quintela A, Vidal C, Carlsen BC, Johansen JD, Menné T, Stender S, Melgaard M, Szecsi PB, Berg ND, Thyssen JP.

Int Arch Allergy Immunol. 2013;161(3):234-42. doi: 10.1159/000345949. Epub 2013 Mar 15.


No remarkable differences in rates of sensitization to common type I and IV allergens between FLG loss-of-function mutation carriers and wild-type subjects.

Landeck L, Visser M, Skudlik C, Brans R, Kezic S, John SM.

Contact Dermatitis. 2014 Jan;70(1):27-34. doi: 10.1111/cod.12109. Epub 2013 Jul 15.


Atopy and development of cancer: a population-based prospective study.

Skaaby T, Nystrup Husemoen LL, Roswall N, Thuesen BH, Linneberg A.

J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):779-85. doi: 10.1016/j.jaip.2014.06.010. Epub 2014 Aug 28.


Filaggrin loss-of-function mutations are associated with early-onset eczema, eczema severity and transepidermal water loss at 3 months of age.

Flohr C, England K, Radulovic S, McLean WH, Campbel LE, Barker J, Perkin M, Lack G.

Br J Dermatol. 2010 Dec;163(6):1333-6.


Genotype-phenotype associations in filaggrin loss-of-function mutation carriers.

Landeck L, Visser M, Kezic S, John SM.

Contact Dermatitis. 2013 Mar;68(3):149-55. doi: 10.1111/j.1600-0536.2012.02171.x.


Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis.

Winge MC, Bilcha KD, Liedén A, Shibeshi D, Sandilands A, Wahlgren CF, McLean WH, Nordenskjöld M, Bradley M.

Br J Dermatol. 2011 Nov;165(5):1074-80. doi: 10.1111/j.1365-2133.2011.10475.x. Epub 2011 Oct 17.


Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.

Brough HA, Simpson A, Makinson K, Hankinson J, Brown S, Douiri A, Belgrave DC, Penagos M, Stephens AC, McLean WH, Turcanu V, Nicolaou N, Custovic A, Lack G.

J Allergy Clin Immunol. 2014 Oct;134(4):867-875.e1. doi: 10.1016/j.jaci.2014.08.011.


Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence.

Venkataraman D, Soto-Ramírez N, Kurukulaaratchy RJ, Holloway JW, Karmaus W, Ewart SL, Arshad SH, Erlewyn-Lajeunesse M.

J Allergy Clin Immunol. 2014 Oct;134(4):876-882.e4. doi: 10.1016/j.jaci.2014.07.033. Epub 2014 Aug 28.


Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.

Joensen UN, Jørgensen N, Meldgaard M, Frederiksen H, Andersson AM, Menné T, Johansen JD, Carlsen BC, Stender S, Szecsi PB, Skakkebæk NE, Rajpert-De Meyts E, Thyssen JP.

Environ Health Perspect. 2014 Apr;122(4):345-50. doi: 10.1289/ehp.1306720. Epub 2014 Jan 3.


Anatomical patterns of dermatitis in adult filaggrin mutation carriers.

Heede NG, Thyssen JP, Thuesen BH, Linneberg A, Johansen JD.

J Am Acad Dermatol. 2015 Mar;72(3):440-8. doi: 10.1016/j.jaad.2015.01.001. Epub 2015 Feb 7.


Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

Brown SJ, Relton CL, Liao H, Zhao Y, Sandilands A, McLean WH, Cordell HJ, Reynolds NJ.

Br J Dermatol. 2009 Oct;161(4):884-9. doi: 10.1111/j.1365-2133.2009.09339.x. Epub 2009 Jun 11.


Interaction between filaggrin null mutations and tobacco smoking in relation to asthma.

Berg ND, Husemoen LL, Thuesen BH, Hersoug LG, Elberling J, Thyssen JP, Carlsen BC, Johansen JD, Menné T, Bønnelykke K, Stender S, Meldgaard M, Szecsi PB, Linneberg A.

J Allergy Clin Immunol. 2012 Feb;129(2):374-80, 380.e1-2. doi: 10.1016/j.jaci.2011.08.045. Epub 2011 Nov 16.

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