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Results: 1 to 20 of 112

1.

ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.

Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH.

J Immunol. 2014 Apr 15;192(8):3475-87. doi: 10.4049/jimmunol.1303047. Epub 2014 Mar 12.

PMID:
24623133
[PubMed - indexed for MEDLINE]
2.

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.

Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16648-53. doi: 10.1073/pnas.1204151109. Epub 2012 Sep 24.

PMID:
23011799
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice.

Qin XJ, Zhang GS, Zhang X, Qiu ZW, Wang PL, Li YW, Li W, Xie QM, Ke YH, Lee JJ, Shen HH.

Allergy. 2012 Dec;67(12):1547-56. doi: 10.1111/all.12048. Epub 2012 Oct 11.

PMID:
23057634
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model.

Baek KJ, Cho JY, Rosenthal P, Alexander LE, Nizet V, Broide DH.

Clin Immunol. 2013 Apr;147(1):27-37. doi: 10.1016/j.clim.2013.02.004. Epub 2013 Feb 21.

PMID:
23499929
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Allergen-induced airway remodeling is impaired in galectin-3-deficient mice.

Ge XN, Bahaie NS, Kang BN, Hosseinkhani MR, Ha SG, Frenzel EM, Liu FT, Rao SP, Sriramarao P.

J Immunol. 2010 Jul 15;185(2):1205-14. doi: 10.4049/jimmunol.1000039. Epub 2010 Jun 11.

PMID:
20543100
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model.

Gregory LG, Jones CP, Mathie SA, Pegorier S, Lloyd CM.

Allergy. 2013 Dec;68(12):1579-88. doi: 10.1111/all.12271. Epub 2013 Oct 14.

PMID:
24117726
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice.

Min MG, Song DJ, Miller M, Cho JY, McElwain S, Ferguson P, Broide DH.

J Immunol. 2007 Apr 15;178(8):5321-8.

PMID:
17404317
[PubMed - indexed for MEDLINE]
Free Article
8.

Toll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergen.

Song DJ, Min MG, Miller M, Cho JY, Yum HY, Broide DH.

Int Arch Allergy Immunol. 2010;151(4):285-96. doi: 10.1159/000250437. Epub 2009 Oct 22.

PMID:
19851071
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

Kiwamoto T, Ishii Y, Morishima Y, Yoh K, Maeda A, Ishizaki K, Iizuka T, Hegab AE, Matsuno Y, Homma S, Nomura A, Sakamoto T, Takahashi S, Sekizawa K.

Am J Respir Crit Care Med. 2006 Jul 15;174(2):142-51. Epub 2006 Apr 13.

PMID:
16614350
[PubMed - indexed for MEDLINE]
10.

Enhanced airway Th2 response after allergen challenge in mice deficient in CC chemokine receptor-2 (CCR2).

Kim Y, Sung Ss, Kuziel WA, Feldman S, Fu SM, Rose CE Jr.

J Immunol. 2001 Apr 15;166(8):5183-92.

PMID:
11290802
[PubMed - indexed for MEDLINE]
Free Article
11.

The presence of LPS in OVA inhalations affects airway inflammation and AHR but not remodeling in a rodent model of asthma.

Tsuchiya K, Siddiqui S, Risse PA, Hirota N, Martin JG.

Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L54-63. doi: 10.1152/ajplung.00208.2011. Epub 2012 Apr 20.

PMID:
22523281
[PubMed - indexed for MEDLINE]
Free Article
12.

Allergen-induced coexpression of bFGF and TGF-β1 by macrophages in a mouse model of airway remodeling: bFGF induces macrophage TGF-β1 expression in vitro.

Yum HY, Cho JY, Miller M, Broide DH.

Int Arch Allergy Immunol. 2011;155(1):12-22. doi: 10.1159/000317213. Epub 2010 Nov 25.

PMID:
21109744
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma.

Mabalirajan U, Aich J, Agrawal A, Ghosh B.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L411-9. doi: 10.1152/ajplung.00138.2009. Epub 2009 Jun 19.

PMID:
19542246
[PubMed - indexed for MEDLINE]
Free Article
14.

Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6 and BALB/c mice.

Van Hove CL, Maes T, Cataldo DD, Guéders MM, Palmans E, Joos GF, Tournoy KG.

Int Arch Allergy Immunol. 2009;149(3):195-207. doi: 10.1159/000199715. Epub 2009 Feb 12.

PMID:
19218812
[PubMed - indexed for MEDLINE]
15.

A single DH gene segment is sufficient for the establishment of an asthma phenotype in a murine model of allergic airway inflammation.

Kerzel S, Rogosch T, Wagner J, Preisser K, Yildirim AÖ, Fehrenbach H, Garn H, Maier RF, Schroeder HW Jr, Zemlin M.

Int Arch Allergy Immunol. 2011;156(3):247-58. doi: 10.1159/000323527. Epub 2011 Jun 29.

PMID:
21720170
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Soluble IL-4 receptor inhibits airway inflammation following allergen challenge in a mouse model of asthma.

Henderson WR Jr, Chi EY, Maliszewski CR.

J Immunol. 2000 Jan 15;164(2):1086-95.

PMID:
10623860
[PubMed - indexed for MEDLINE]
Free Article
17.

Annexin-1-deficient mice exhibit spontaneous airway hyperresponsiveness and exacerbated allergen-specific antibody responses in a mouse model of asthma.

Ng FS, Wong KY, Guan SP, Mustafa FB, Kajiji TS, Bist P, Biswas SK, Wong WS, Lim LH.

Clin Exp Allergy. 2011 Dec;41(12):1793-803. doi: 10.1111/j.1365-2222.2011.03855.x. Epub 2011 Sep 20.

PMID:
22092555
[PubMed - indexed for MEDLINE]
18.

Natural killer T cells are dispensable in the development of allergen-induced airway hyperresponsiveness, inflammation and remodelling in a mouse model of chronic asthma.

Koh YI, Shim JU, Lee JH, Chung IJ, Min JJ, Rhee JH, Lee HC, Chung DH, Wi JO.

Clin Exp Immunol. 2010 Jul 1;161(1):159-70. doi: 10.1111/j.1365-2249.2010.04151.x. Epub 2010 Apr 29.

PMID:
20456411
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Xiao-Qing-Long-Tang attenuates allergic airway inflammation and remodeling in repetitive Dermatogoides pteronyssinus challenged chronic asthmatic mice model.

Wang SD, Lin LJ, Chen CL, Lee SC, Lin CC, Wang JY, Kao ST.

J Ethnopharmacol. 2012 Jul 13;142(2):531-8. doi: 10.1016/j.jep.2012.05.033. Epub 2012 Jun 1.

PMID:
22658987
[PubMed - indexed for MEDLINE]
20.

Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.

Chen ZG, Zhang TT, Li HT, Chen FH, Zou XL, Ji JZ, Chen H.

PLoS One. 2013;8(1):e51268. doi: 10.1371/journal.pone.0051268. Epub 2013 Jan 2.

PMID:
23300949
[PubMed - indexed for MEDLINE]
Free PMC Article

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