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Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line.

Li W, Wang W, Li Y, Wang W, Wang T, Li L, Han Z, Wang S, Ma D, Wang H.

PLoS One. 2014 Mar 12;9(3):e90114. doi: 10.1371/journal.pone.0090114. eCollection 2014.


Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78.

Li W, Wang W, Dong H, Li Y, Li L, Han L, Han Z, Wang S, Ma D, Wang H.

Oncol Rep. 2014 Jun;31(6):2525-34. doi: 10.3892/or.2014.3147. Epub 2014 Apr 23.


Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78.

Kishi S, Shimoke K, Nakatani Y, Shimada T, Okumura N, Nagai K, Shin-Ya K, Ikeuchi T.

Neurosci Res. 2010 Jan;66(1):14-21. doi: 10.1016/j.neures.2009.09.003. Epub 2009 Sep 18.


A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance.

Wansleben S, Davis E, Peres J, Prince S.

Cell Death Dis. 2013 Oct 10;4:e846. doi: 10.1038/cddis.2013.365.


RECK regulated endoplasmic reticulum stress response and enhanced cisplatin-induced cell death in neuroblastoma cells.

Chen Y, Tsai YH, Tseng SH.

Surgery. 2013 Nov;154(5):968-79. doi: 10.1016/j.surg.2013.05.026. Epub 2013 Sep 29.


GRP78 upregulation-induced increase in cisplatin sensitivity of SPCA1 lung cancer cells.

Zhang LC, Wang JR, Zhao L, Wang T, Wu J, Fan SF, Chen LX, Shao SJ, Molnár J, Wang Q.

Chin Med J (Engl). 2011 Oct;124(20):3341-6.


Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells.

Lin Y, Wang Z, Liu L, Chen L.

Lung Cancer. 2011 Mar;71(3):291-7. doi: 10.1016/j.lungcan.2010.06.004.


Reactive oxygen species generation is essential for cisplatin-induced accelerated senescence in hepatocellular carcinoma.

Qu K, Lin T, Wang Z, Liu S, Chang H, Xu X, Meng F, Zhou L, Wei J, Tai M, Dong Y, Liu C.

Front Med. 2014 Jun;8(2):227-35. doi: 10.1007/s11684-014-0327-1. Epub 2014 Apr 22.


ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.

Pabla N, Huang S, Mi QS, Daniel R, Dong Z.

J Biol Chem. 2008 Mar 7;283(10):6572-83. Epub 2007 Dec 27. Erratum in: J Biol Chem. 2008 May 30;283(22):15512.


Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells.

Zu K, Bihani T, Lin A, Park YM, Mori K, Ip C.

Oncogene. 2006 Jan 26;25(4):546-54.


[The role of GRP78 on the resistance to cisplatin in SPCA-1 cell line].

Wu J, Wang Q, Wang J, Zhang L, Zhao L.

Zhongguo Fei Ai Za Zhi. 2010 Jan;13(1):38-41. doi: 10.3779/j.issn.1009-3419.2010.01.07. Chinese.


Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent.

Chao SK, Lin J, Brouwer-Visser J, Smith AB 3rd, Horwitz SB, McDaid HM.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):391-6. doi: 10.1073/pnas.1016962108. Epub 2010 Dec 20.


Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78.

Tsai HY, Yang YF, Wu AT, Yang CJ, Liu YP, Jan YH, Lee CH, Hsiao YW, Yeh CT, Shen CN, Lu PJ, Huang MS, Hsiao M.

Oncogene. 2013 Oct 10;32(41):4921-31. doi: 10.1038/onc.2012.514. Epub 2013 Jan 14.


Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells.

Zhang JW, Zhang SS, Song JR, Sun K, Zong C, Zhao QD, Liu WT, Li R, Wu MC, Wei LX.

Biochem Pharmacol. 2014 Aug 1;90(3):265-75. doi: 10.1016/j.bcp.2014.05.009. Epub 2014 May 22.


UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.

Zhang XW, Wang XF, Ni SJ, Qin W, Zhao LQ, Hua RX, Lu YW, Li J, Dimri GP, Guo WJ.

J Pathol. 2015 Mar;235(4):656-67. doi: 10.1002/path.4478. Epub 2015 Jan 7.


[Inhibition of GRP78 expression reverses cisplatin resistance in human ovarian cancer].

Fan LM, Su J, Dong H, Wei M, Cui MH.

Zhonghua Yi Xue Za Zhi. 2013 May 7;93(17):1341-4. Chinese.


Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin.

Shi Y, Felley-Bosco E, Marti TM, Orlowski K, Pruschy M, Stahel RA.

BMC Cancer. 2012 Dec 4;12:571. doi: 10.1186/1471-2407-12-571.


Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.

López-Vicente L, Armengol G, Pons B, Coch L, Argelaguet E, Lleonart M, Hernández-Losa J, de Torres I, Ramon y Cajal S.

Clin Cancer Res. 2009 Jul 15;15(14):4546-53. doi: 10.1158/1078-0432.CCR-08-3159. Epub 2009 Jul 7.


Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells.

Jiang CC, Mao ZG, Avery-Kiejda KA, Wade M, Hersey P, Zhang XD.

Carcinogenesis. 2009 Feb;30(2):197-204. doi: 10.1093/carcin/bgn220. Epub 2008 Oct 8.

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