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Items: 1 to 20 of 103

1.

Deletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity.

Bennett G, Strissel KJ, DeFuria J, Wang J, Wu D, Burkly LC, Obin MS.

Obesity (Silver Spring). 2014 Jun;22(6):1485-94. doi: 10.1002/oby.20726. Epub 2014 Mar 8.

2.

Tumor necrosis-like weak inducer of apoptosis as a proinflammatory cytokine in human adipocyte cells: up-regulation in severe obesity is mediated by inflammation but not hypoxia.

Vendrell J, Maymó-Masip E, Tinahones F, García-España A, Megia A, Caubet E, García-Fuentes E, Chacón MR.

J Clin Endocrinol Metab. 2010 Jun;95(6):2983-92. doi: 10.1210/jc.2009-2481. Epub 2010 Apr 9.

PMID:
20382683
3.

Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice.

Tarín C, Fernández-Laso V, Sastre C, Madrigal-Matute J, Gómez M, Zaragoza C, Egido J, Burkly LC, Martín-Ventura JL, Blanco-Colio LM.

J Am Heart Assoc. 2014 Aug 4;3(4). pii: e000723. doi: 10.1161/JAHA.113.000723. Erratum in: J Am Heart Assoc. 2014 Oct;3(5):000509.

4.

Effects of TWEAK (TNF superfamily member 12) on differentiation, metabolism, and secretory function of human primary preadipocytes and adipocytes.

Tiller G, Fischer-Posovszky P, Laumen H, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H.

Endocrinology. 2009 Dec;150(12):5373-83. doi: 10.1210/en.2009-0488. Epub 2009 Nov 3.

PMID:
19887572
5.

Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis.

McGillicuddy FC, Harford KA, Reynolds CM, Oliver E, Claessens M, Mills KH, Roche HM.

Diabetes. 2011 Jun;60(6):1688-98. doi: 10.2337/db10-1278. Epub 2011 Apr 22.

6.

TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.

Karaca G, Swiderska-Syn M, Xie G, Syn WK, Krüger L, Machado MV, Garman K, Choi SS, Michelotti GA, Burkly LC, Ochoa B, Diehl AM.

PLoS One. 2014 Jan 9;9(1):e83987. doi: 10.1371/journal.pone.0083987. eCollection 2014.

7.
8.
9.

Role of Fn14 in acute alcoholic steatohepatitis in mice.

Karaca G, Xie G, Moylan C, Swiderska-Syn M, Guy CD, Krüger L, Machado MV, Choi SS, Michelotti GA, Burkly LC, Diehl AM.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G325-34. doi: 10.1152/ajpgi.00429.2013. Epub 2014 Dec 18.

PMID:
25524063
10.

TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice.

Son A, Oshio T, Kawamura YI, Hagiwara T, Yamazaki M, Inagaki-Ohara K, Okada T, Wu P, Iseki M, Takaki S, Burkly LC, Dohi T.

Mucosal Immunol. 2013 Nov;6(6):1131-42. doi: 10.1038/mi.2013.10. Epub 2013 Mar 6.

PMID:
23462911
11.

TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.

Dohi T, Borodovsky A, Wu P, Shearstone JR, Kawashima R, Runkel L, Rajman L, Dong X, Scott ML, Michaelson JS, Jakubowski A, Burkly LC.

Gastroenterology. 2009 Mar;136(3):912-23. doi: 10.1053/j.gastro.2008.11.017. Epub 2008 Nov 8.

PMID:
19109961
12.

Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death.

Haile WB, Echeverry R, Wu F, Guzman J, An J, Wu J, Yepes M.

Neuroscience. 2010 Dec 29;171(4):1256-64. doi: 10.1016/j.neuroscience.2010.10.029. Epub 2010 Oct 16.

13.

TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization.

Ameri H, Liu H, Liu R, Ha Y, Paulucci-Holthauzen AA, Hu S, Motamedi M, Godley BF, Tilton RG, Zhang W.

Invest Ophthalmol Vis Sci. 2014 Feb 10;55(2):801-13. doi: 10.1167/iovs.13-12812.

14.

A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure.

Jain M, Jakubowski A, Cui L, Shi J, Su L, Bauer M, Guan J, Lim CC, Naito Y, Thompson JS, Sam F, Ambrose C, Parr M, Crowell T, Lincecum JM, Wang MZ, Hsu YM, Zheng TS, Michaelson JS, Liao R, Burkly LC.

Circulation. 2009 Apr 21;119(15):2058-68. doi: 10.1161/CIRCULATIONAHA.108.837286. Epub 2009 Apr 6.

15.

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.

Chapman J, Miles PD, Ofrecio JM, Neels JG, Yu JG, Resnik JL, Wilkes J, Talukdar S, Thapar D, Johnson K, Sears DD.

PLoS One. 2010 Nov 12;5(11):e13959. doi: 10.1371/journal.pone.0013959.

16.

TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses.

Burkly LC, Michaelson JS, Zheng TS.

Immunol Rev. 2011 Nov;244(1):99-114. doi: 10.1111/j.1600-065X.2011.01054.x. Review.

PMID:
22017434
17.

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells.

Tirnitz-Parker JE, Viebahn CS, Jakubowski A, Klopcic BR, Olynyk JK, Yeoh GC, Knight B.

Hepatology. 2010 Jul;52(1):291-302. doi: 10.1002/hep.23663.

PMID:
20578156
18.

TWEAK induces liver progenitor cell proliferation.

Jakubowski A, Ambrose C, Parr M, Lincecum JM, Wang MZ, Zheng TS, Browning B, Michaelson JS, Baetscher M, Wang B, Bissell DM, Burkly LC.

J Clin Invest. 2005 Sep;115(9):2330-40. Epub 2005 Aug 18. Erratum in: J Clin Invest. 2005 Oct;115(10):2955. Baestcher, Manfred [corrected to Baetscher, Manfred].

19.

Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice.

Jaworski DM, Sideleva O, Stradecki HM, Langlois GD, Habibovic A, Satish B, Tharp WG, Lausier J, Larock K, Jetton TL, Peshavaria M, Pratley RE.

Endocrinology. 2011 Apr;152(4):1300-13. doi: 10.1210/en.2010-1029. Epub 2011 Feb 1.

20.

Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis.

Xia Y, Campbell SR, Broder A, Herlitz L, Abadi M, Wu P, Michaelson JS, Burkly LC, Putterman C.

Clin Immunol. 2012 Nov;145(2):108-21. doi: 10.1016/j.clim.2012.08.008. Epub 2012 Aug 20.

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