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Items: 1 to 20 of 122

1.

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP.

J Clin Invest. 2014 Apr;124(4):1685-98. doi: 10.1172/JCI69780. Epub 2014 Mar 10.

2.

Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function.

Zhang L, Tschumi BO, Corgnac S, Rüegg MA, Hall MN, Mach JP, Romero P, Donda A.

J Immunol. 2014 Aug 15;193(4):1759-65. doi: 10.4049/jimmunol.1400769. Epub 2014 Jul 11.

3.

Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.

Prevot N, Pyaram K, Bischoff E, Sen JM, Powell JD, Chang CH.

J Immunol. 2015 Jan 1;194(1):223-30. doi: 10.4049/jimmunol.1401985. Epub 2014 Nov 17.

4.

Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cell-mediated antitumor immunity.

Wu J, Shin J, Xie D, Wang H, Gao J, Zhong XP.

J Immunol. 2014 Mar 15;192(6):2643-50. doi: 10.4049/jimmunol.1302076. Epub 2014 Feb 14.

5.

mTOR and its tight regulation for iNKT cell development and effector function.

Yang W, Gorentla B, Zhong XP, Shin J.

Mol Immunol. 2015 Dec;68(2 Pt C):536-45. doi: 10.1016/j.molimm.2015.07.022. Epub 2015 Aug 4. Review.

PMID:
26253278
7.

Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation.

Castillo EF, Acero LF, Stonier SW, Zhou D, Schluns KS.

Blood. 2010 Oct 7;116(14):2494-503. doi: 10.1182/blood-2010-03-277103. Epub 2010 Jun 25.

8.

A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells.

Klose CS, Kiss EA, Schwierzeck V, Ebert K, Hoyler T, d'Hargues Y, Göppert N, Croxford AL, Waisman A, Tanriver Y, Diefenbach A.

Nature. 2013 Feb 14;494(7436):261-5. doi: 10.1038/nature11813. Epub 2013 Jan 16.

PMID:
23334414
9.

Invariant NKT cells inhibit development of the Th17 lineage.

Mars LT, Araujo L, Kerschen P, Diem S, Bourgeois E, Van LP, Carrié N, Dy M, Liblau RS, Herbelin A.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6238-43. doi: 10.1073/pnas.0809317106. Epub 2009 Mar 26.

10.

Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell.

Qi Q, Xia M, Bai Y, Yu S, Cantorna M, August A.

J Biol Chem. 2011 Jan 7;286(1):138-46. doi: 10.1074/jbc.M110.148205. Epub 2010 Oct 29.

11.

Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation.

Michel ML, Mendes-da-Cruz D, Keller AC, Lochner M, Schneider E, Dy M, Eberl G, Leite-de-Moraes MC.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19845-50. doi: 10.1073/pnas.0806472105. Epub 2008 Dec 4.

12.

Essential role of Mediator subunit Med1 in invariant natural killer T-cell development.

Yue X, Izcue A, Borggrefe T.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17105-10. doi: 10.1073/pnas.1109095108. Epub 2011 Sep 26.

13.

Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control.

Havenar-Daughton C, Li S, Benlagha K, Marie JC.

Blood. 2012 Apr 12;119(15):3486-94. doi: 10.1182/blood-2012-01-401604. Epub 2012 Feb 27.

14.

Differential dependence on nuclear factor-κB-inducing kinase among natural killer T-cell subsets in their development.

Noma H, Eshima K, Satoh M, Iwabuchi K.

Immunology. 2015 Sep;146(1):89-99. doi: 10.1111/imm.12484. Epub 2015 Jun 25.

PMID:
25988531
15.

Critical role for invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells.

Sillé FC, Martin C, Jayaraman P, Rothchild A, Besra GS, Behar SM, Boes M.

Immunol Lett. 2011 Sep 30;139(1-2):33-41. doi: 10.1016/j.imlet.2011.04.012. Epub 2011 May 5.

16.

Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.

Park H, Tsang M, Iritani BM, Bevan MJ.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):7066-71. doi: 10.1073/pnas.1406473111. Epub 2014 Apr 30.

17.

Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.

Shrestha S, Yang K, Wei J, Karmaus PW, Neale G, Chi H.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14858-63. doi: 10.1073/pnas.1404264111. Epub 2014 Sep 30.

18.

Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.

Pan H, O'Brien TF, Wright G, Yang J, Shin J, Wright KL, Zhong XP.

J Immunol. 2013 Jul 15;191(2):699-707. doi: 10.4049/jimmunol.1201443. Epub 2013 Jun 17.

19.

IL-15 regulates homeostasis and terminal maturation of NKT cells.

Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S.

J Immunol. 2011 Dec 15;187(12):6335-45. doi: 10.4049/jimmunol.1003965. Epub 2011 Nov 14.

20.

The development of airway hyperreactivity in T-bet-deficient mice requires CD1d-restricted NKT cells.

Kim HY, Pichavant M, Matangkasombut P, Koh YI, Savage PB, DeKruyff RH, Umetsu DT.

J Immunol. 2009 Mar 1;182(5):3252-61. doi: 10.4049/jimmunol.0803339.

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