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Results: 1 to 20 of 111

1.

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans.

Huh JY, Dincer F, Mesfum E, Mantzoros CS.

Int J Obes (Lond). 2014 Mar 11. doi: 10.1038/ijo.2014.42. [Epub ahead of print]

PMID:
24614098
[PubMed - as supplied by publisher]
2.

Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance.

Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E, Pardo G, Tinahones F, Ricart W, Fernández-Real JM.

J Clin Endocrinol Metab. 2013 Apr;98(4):E769-78. doi: 10.1210/jc.2012-2749. Epub 2013 Feb 22.

PMID:
23436919
[PubMed - indexed for MEDLINE]
3.

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.

Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, Schneider BE, Mantzoros CS.

Metabolism. 2012 Dec;61(12):1725-38. doi: 10.1016/j.metabol.2012.09.002. Epub 2012 Sep 25.

PMID:
23018146
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice.

Rodríguez A, Becerril S, Méndez-Giménez L, Ramírez B, Sáinz N, Catalán V, Gómez-Ambrosi J, Frühbeck G.

Int J Obes (Lond). 2014 Sep 9. doi: 10.1038/ijo.2014.166. [Epub ahead of print]

PMID:
25199621
[PubMed - as supplied by publisher]
5.

Evidence against a beneficial effect of irisin in humans.

Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, Jung R, Wisløff U, Tjønna AE, Raastad T, Hallén J, Norheim F, Drevon CA, Romacho T, Eckardt K, Eckel J.

PLoS One. 2013 Sep 11;8(9):e73680. doi: 10.1371/journal.pone.0073680. eCollection 2013.

PMID:
24040023
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes.

Kurdiova T, Balaz M, Mayer A, Maderova D, Belan V, Wolfrum C, Ukropec J, Ukropcova B.

Peptides. 2014 Jun;56:1-7. doi: 10.1016/j.peptides.2014.03.003. Epub 2014 Mar 16.

PMID:
24642356
[PubMed - in process]
7.

Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.

Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, Srbecky M, Imrich R, Kyselovicova O, Belan V, Jelok I, Wolfrum C, Klimes I, Krssak M, Zemkova E, Gasperikova D, Ukropec J, Ukropcova B.

J Physiol. 2014 Mar 1;592(Pt 5):1091-107. doi: 10.1113/jphysiol.2013.264655. Epub 2013 Dec 2.

PMID:
24297848
[PubMed - in process]
8.

Browning of white fat: does irisin play a role in humans?

Elsen M, Raschke S, Eckel J.

J Endocrinol. 2014 Jul;222(1):R25-38. doi: 10.1530/JOE-14-0189. Epub 2014 Apr 29.

PMID:
24781257
[PubMed - in process]
9.

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle.

Shan T, Liang X, Bi P, Kuang S.

FASEB J. 2013 May;27(5):1981-9. doi: 10.1096/fj.12-225755. Epub 2013 Jan 29.

PMID:
23362117
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.

Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, Qi L, Zhang M, Wang X, Cui T, Yang LJ, Tang D.

Diabetes. 2014 Feb;63(2):514-25. doi: 10.2337/db13-1106. Epub 2013 Oct 22.

PMID:
24150604
[PubMed - indexed for MEDLINE]
Free Article
11.

Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.

Lee P, Linderman JD, Smith S, Brychta RJ, Wang J, Idelson C, Perron RM, Werner CD, Phan GQ, Kammula US, Kebebew E, Pacak K, Chen KY, Celi FS.

Cell Metab. 2014 Feb 4;19(2):302-9. doi: 10.1016/j.cmet.2013.12.017.

PMID:
24506871
[PubMed - in process]
12.

Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs.

Fain JN, Company JM, Booth FW, Laughlin MH, Padilla J, Jenkins NT, Bahouth SW, Sacks HS.

Metabolism. 2013 Oct;62(10):1503-11. doi: 10.1016/j.metabol.2013.05.021. Epub 2013 Jul 5.

PMID:
23831442
[PubMed - indexed for MEDLINE]
13.

Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle?

Komolka K, Albrecht E, Schering L, Brenmoehl J, Hoeflich A, Maak S.

PLoS One. 2014 Jan 31;9(1):e88060. doi: 10.1371/journal.pone.0088060. eCollection 2014.

PMID:
24498244
[PubMed - in process]
Free PMC Article
14.

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity.

Staiger H, Böhm A, Scheler M, Berti L, Machann J, Schick F, Machicao F, Fritsche A, Stefan N, Weigert C, Krook A, Häring HU, de Angelis MH.

PLoS One. 2013 Apr 25;8(4):e61903. doi: 10.1371/journal.pone.0061903. Print 2013.

PMID:
23637927
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Does IRISIN Have a BRITE Future as a Therapeutic Agent in Humans?

Irving BA, Still CD, Argyropoulos G.

Curr Obes Rep. 2014 Feb 2;3:235-241. eCollection 2014. Review.

PMID:
24818073
[PubMed]
Free PMC Article
16.

Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?

Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, Mäkelä KA, Kainulainen H, Häkkinen K, Nyman K, Alén M, Herzig KH, Cheng S.

J Physiol. 2013 Nov 1;591(Pt 21):5393-400. doi: 10.1113/jphysiol.2013.263707. Epub 2013 Sep 2.

PMID:
24000180
[PubMed - in process]
17.

Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?

Erickson HP.

Adipocyte. 2013 Oct 1;2(4):289-93. doi: 10.4161/adip.26082. Epub 2013 Aug 19.

PMID:
24052909
[PubMed]
Free PMC Article
18.

FNDC5/irisin is not only a myokine but also an adipokine.

Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Belén Crujeiras A, Seoane LM, Casanueva FF, Pardo M.

PLoS One. 2013 Apr 11;8(4):e60563. doi: 10.1371/journal.pone.0060563. Print 2013.

PMID:
23593248
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Characterization of the metabolic effects of irisin on skeletal muscle in vitro.

Vaughan RA, Gannon NP, Barberena MA, Garcia-Smith R, Bisoffi M, Mermier CM, Conn CA, Trujillo KA.

Diabetes Obes Metab. 2014 Aug;16(8):711-8. doi: 10.1111/dom.12268. Epub 2014 Feb 18.

PMID:
24476050
[PubMed - in process]
20.

Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo.

Gouni-Berthold I, Berthold HK, Huh JY, Berman R, Spenrath N, Krone W, Mantzoros CS.

PLoS One. 2013 Sep 2;8(9):e72858. doi: 10.1371/journal.pone.0072858. eCollection 2013.

PMID:
24023786
[PubMed - indexed for MEDLINE]
Free PMC Article

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