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Items: 1 to 20 of 135

1.
2.

Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts.

Chen H, Parkinson JA, Parsons S, Coxall RA, Gould RO, Sadler PJ.

J Am Chem Soc. 2002 Mar 27;124(12):3064-82.

PMID:
11902898
3.

Ruthenium-arene complexes of curcumin: X-ray and density functional theory structure, synthesis, and spectroscopic characterization, in vitro antitumor activity, and DNA docking studies of (p-cymene)Ru(curcuminato)chloro.

Caruso F, Rossi M, Benson A, Opazo C, Freedman D, Monti E, Gariboldi MB, Shaulky J, Marchetti F, Pettinari R, Pettinari C.

J Med Chem. 2012 Feb 9;55(3):1072-81. doi: 10.1021/jm200912j. Epub 2012 Jan 20.

PMID:
22204522
4.

Anticancer activity and DNA binding of a bifunctional Ru(II) arene aqua-complex with the 2,4-diamino-6-(2-pyridyl)-1,3,5-triazine ligand.

Busto N, Valladolid J, Martínez-Alonso M, Lozano HJ, Jalón FA, Manzano BR, Rodríguez AM, Carrión MC, Biver T, Leal JM, Espino G, García B.

Inorg Chem. 2013 Sep 3;52(17):9962-74. doi: 10.1021/ic401197a. Epub 2013 Aug 20.

PMID:
23957818
5.

Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity.

Betanzos-Lara S, Novakova O, Deeth RJ, Pizarro AM, Clarkson GJ, Liskova B, Brabec V, Sadler PJ, Habtemariam A.

J Biol Inorg Chem. 2012 Oct;17(7):1033-51. doi: 10.1007/s00775-012-0917-9. Epub 2012 Jul 12.

PMID:
22791215
6.

Metal complexes as DNA intercalators.

Liu HK, Sadler PJ.

Acc Chem Res. 2011 May 17;44(5):349-59. doi: 10.1021/ar100140e. Epub 2011 Mar 29.

PMID:
21446672
7.

The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes.

Bugarcic T, Habtemariam A, Stepankova J, Heringova P, Kasparkova J, Deeth RJ, Johnstone RD, Prescimone A, Parkin A, Parsons S, Brabec V, Sadler PJ.

Inorg Chem. 2008 Dec 15;47(24):11470-86. doi: 10.1021/ic801361m.

PMID:
19007206
8.

A novel ruthenium(II) arene based intercalator with potent anticancer activity.

Ruiz J, Vicente C, de Haro C, Bautista D.

Dalton Trans. 2009 Jul 14;(26):5071-3. doi: 10.1039/b907296a. Epub 2009 May 12.

PMID:
19562164
9.

Chloro half-sandwich osmium(II) complexes: influence of chelated N,N-ligands on hydrolysis, guanine binding, and cytotoxicity.

Peacock AF, Habtemariam A, Moggach SA, Prescimone A, Parsons S, Sadler PJ.

Inorg Chem. 2007 May 14;46(10):4049-59. Epub 2007 Apr 19.

PMID:
17441712
10.

Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter?

Hanif M, Henke H, Meier SM, Martic S, Labib M, Kandioller W, Jakupec MA, Arion VB, Kraatz HB, Keppler BK, Hartinger CG.

Inorg Chem. 2010 Sep 6;49(17):7953-63. doi: 10.1021/ic1009785.

PMID:
20704358
11.

Chlorido-, aqua-, 9-ethylguanine- and 9-ethyladenine-adducts of cytotoxic ruthenium arene complexes containing O,O-chelating ligands.

Melchart M, Habtemariam A, Parsons S, Sadler PJ.

J Inorg Biochem. 2007 Nov;101(11-12):1903-12. Epub 2007 May 10.

PMID:
17582501
12.

Ferrocenoyl pyridine arene ruthenium complexes with anticancer properties: synthesis, structure, electrochemistry, and cytotoxicity.

Auzias M, Therrien B, Süss-Fink G, Stepnicka P, Ang WH, Dyson PJ.

Inorg Chem. 2008 Jan 21;47(2):578-83. Epub 2007 Dec 18.

PMID:
18085776
13.

Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure.

Gligorijević N, Aranđelović S, Filipović L, Jakovljević K, Janković R, Grgurić-Šipka S, Ivanović I, Radulović S, Tešić ZLj.

J Inorg Biochem. 2012 Mar;108:53-61. doi: 10.1016/j.jinorgbio.2011.12.002. Epub 2011 Dec 16.

PMID:
22266461
14.

Phenylazo-pyridine and phenylazo-pyrazole chlorido ruthenium(II) arene complexes: arene loss, aquation, and cancer cell cytotoxicity.

Dougan SJ, Melchart M, Habtemariam A, Parsons S, Sadler PJ.

Inorg Chem. 2006 Dec 25;45(26):10882-94. Erratum in: Inorg Chem. 2007 Feb 19;46(4):1508.

PMID:
17173447
15.

Derivation of structure-activity relationships from the anticancer properties of ruthenium(II) arene complexes with 2-aryldiazole ligands.

Martínez-Alonso M, Busto N, Jalón FA, Manzano BR, Leal JM, Rodríguez AM, García B, Espino G.

Inorg Chem. 2014 Oct 20;53(20):11274-88. doi: 10.1021/ic501865h. Epub 2014 Oct 10.

PMID:
25302401
16.

Ruthenium(II) arene anticancer complexes with redox-active diamine ligands.

Bugarcic T, Habtemariam A, Deeth RJ, Fabbiani FP, Parsons S, Sadler PJ.

Inorg Chem. 2009 Oct 5;48(19):9444-53. doi: 10.1021/ic9013366.

PMID:
19780621
17.

Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine.

Rajapakse CS, Martínez A, Naoulou B, Jarzecki AA, Suárez L, Deregnaucourt C, Sinou V, Schrével J, Musi E, Ambrosini G, Schwartz GK, Sánchez-Delgado RA.

Inorg Chem. 2009 Feb 2;48(3):1122-31. doi: 10.1021/ic802220w.

18.

Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes.

Fernández R, Melchart M, Habtemariam A, Parsons S, Sadler PJ.

Chemistry. 2004 Oct 11;10(20):5173-9.

PMID:
15372674
19.

New ruthenium(II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity.

Ganeshpandian M, Loganathan R, Suresh E, Riyasdeen A, Akbarsha MA, Palaniandavar M.

Dalton Trans. 2014 Jan 21;43(3):1203-19. doi: 10.1039/c3dt51641e. Epub 2013 Oct 31.

PMID:
24177707
20.

Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.

Peacock AF, Habtemariam A, Fernández R, Walland V, Fabbiani FP, Parsons S, Aird RE, Jodrell DI, Sadler PJ.

J Am Chem Soc. 2006 Feb 8;128(5):1739-48.

PMID:
16448150
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