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Items: 1 to 20 of 137

1.

Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model.

Zhu X, Li Q, Chang R, Yang D, Song Z, Guo Q, Huang C.

PLoS One. 2014 Mar 6;9(3):e91303. doi: 10.1371/journal.pone.0091303. eCollection 2014.

2.

p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI).

Zhu XY, Huang CS, Li Q, Chang RM, Song ZB, Zou WY, Guo QL.

Mol Pain. 2012 Nov 23;8:84. doi: 10.1186/1744-8069-8-84.

3.

Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model.

Vanelderen P, Rouwette T, Kozicz T, Heylen R, Van Zundert J, Roubos EW, Vissers K.

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):124-30. doi: 10.1097/AAP.0b013e31827d611b.

PMID:
23337936
4.

Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling.

Xiao X, Shi D, Liu L, Wang J, Xie X, Kang T, Deng W.

PLoS One. 2011;6(8):e22934. doi: 10.1371/journal.pone.0022934. Epub 2011 Aug 8.

5.

Curcumin prevents and reverses murine cardiac hypertrophy.

Li HL, Liu C, de Couto G, Ouzounian M, Sun M, Wang AB, Huang Y, He CW, Shi Y, Chen X, Nghiem MP, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh AK, Kirshenbaum LA, Liu PP.

J Clin Invest. 2008 Mar;118(3):879-93. doi: 10.1172/JCI32865. Retraction in: J Clin Invest. 2009 Jul;119(7):2113.

6.

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription.

Balasubramanyam K, Varier RA, Altaf M, Swaminathan V, Siddappa NB, Ranga U, Kundu TK.

J Biol Chem. 2004 Dec 3;279(49):51163-71. Epub 2004 Sep 20.

7.

Koumine enhances spinal cord 3α-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain.

Qiu HQ, Xu Y, Jin GL, Yang J, Liu M, Li SP, Yu CX.

Mol Pain. 2015 Aug 9;11:46. doi: 10.1186/s12990-015-0050-1.

8.

Resveratrol facilitates pain attenuation in a rat model of neuropathic pain through the activation of spinal Sirt1.

Yin Q, Lu FF, Zhao Y, Cheng MY, Fan Q, Cui J, Liu L, Cheng W, Yan CD.

Reg Anesth Pain Med. 2013 Mar-Apr;38(2):93-9. doi: 10.1097/AAP.0b013e3182795b23.

PMID:
23337935
9.

Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation.

Wang Y, Wang Y, Luo M, Wu H, Kong L, Xin Y, Cui W, Zhao Y, Wang J, Liang G, Miao L, Cai L.

Biochim Biophys Acta. 2015 Jan;1852(1):34-46. doi: 10.1016/j.bbadis.2014.11.006. Epub 2014 Nov 11.

10.

Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation.

Geng SJ, Liao FF, Dang WH, Ding X, Liu XD, Cai J, Han JS, Wan Y, Xing GG.

Exp Neurol. 2010 Apr;222(2):256-66. doi: 10.1016/j.expneurol.2010.01.003. Epub 2010 Jan 14.

PMID:
20079352
11.

Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes.

Sun H, Yang X, Zhu J, Lv T, Chen Y, Chen G, Zhong L, Li Y, Huang X, Huang G, Tian J.

Life Sci. 2010 Dec 18;87(23-26):707-14. doi: 10.1016/j.lfs.2010.10.009. Epub 2010 Oct 26.

PMID:
21034749
13.

Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity.

Kutluay SB, Doroghazi J, Roemer ME, Triezenberg SJ.

Virology. 2008 Apr 10;373(2):239-47. doi: 10.1016/j.virol.2007.11.028. Epub 2008 Jan 14.

14.
15.

The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats.

Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K.

J Clin Invest. 2008 Mar;118(3):868-78. doi: 10.1172/JCI33160.

16.

Regulation of insulin gene transcription by multiple histone acetyltransferases.

Sampley ML, Ozcan S.

DNA Cell Biol. 2012 Jan;31(1):8-14. doi: 10.1089/dna.2011.1336. Epub 2011 Jul 20.

17.

Lumbar transplant of neurons genetically modified to secrete brain-derived neurotrophic factor attenuates allodynia and hyperalgesia after sciatic nerve constriction.

Cejas PJ, Martinez M, Karmally S, McKillop M, McKillop J, Plunkett JA, Oudega M, Eaton MJ.

Pain. 2000 May;86(1-2):195-210.

PMID:
10779676
18.

Brain-derived neurotrophic factor redistribution in the dorsal root ganglia correlates with neuropathic pain inhibition after resiniferatoxin treatment.

Tender GC, Li YY, Cui JG.

Spine J. 2010 Aug;10(8):715-20. doi: 10.1016/j.spinee.2010.03.029. Epub 2010 May 7.

PMID:
20452292
19.

Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells.

Yuan H, Reddy MA, Sun G, Lanting L, Wang M, Kato M, Natarajan R.

Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F601-13. doi: 10.1152/ajprenal.00523.2012. Epub 2012 Dec 12.

20.

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP.

Crump NT, Hazzalin CA, Bowers EM, Alani RM, Cole PA, Mahadevan LC.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7814-9. doi: 10.1073/pnas.1100099108. Epub 2011 Apr 25.

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