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Results: 1 to 20 of 128

1.

Pharmacokinetics of 3 times a day dosing of oral treprostinil in healthy volunteers.

Jones A, Wang-Smith L, Pham T, Laliberte K.

J Cardiovasc Pharmacol. 2014 Mar;63(3):227-32. doi: 10.1097/FJC.0000000000000039.

PMID:
24603117
[PubMed - in process]
3.

Tolerability and pharmacokinetics of ranolazine following single and multiple sustained-release doses in Chinese healthy adult volunteers: a randomized, open-label, Latin square design, phase I study.

Tan QY, Li HD, Zhu RH, Zhang QZ, Zhang J, Peng WX.

Am J Cardiovasc Drugs. 2013 Feb;13(1):17-25. doi: 10.1007/s40256-013-0006-7.

PMID:
23355361
[PubMed - indexed for MEDLINE]
4.

Pharmacokinetics of duloxetine hydrochloride enteric-coated tablets in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study.

Zhao RK, Cheng G, Tang J, Song J, Peng WX.

Clin Ther. 2009 May;31(5):1022-36. doi: 10.1016/j.clinthera.2009.05.005.

PMID:
19539103
[PubMed - indexed for MEDLINE]
6.

An evaluation of the pharmacokinetics of treprostinil diolamine in subjects with hepatic impairment.

Peterson L, Marbury T, Marier J, Laliberte K.

J Clin Pharm Ther. 2013 Dec;38(6):518-23. doi: 10.1111/jcpt.12094. Epub 2013 Aug 28.

PMID:
24033615
[PubMed - in process]
7.
8.

Pharmacokinetic properties of once-daily oral low-dose mesylate salt of paroxetine (LDMP 7.5 mg) following single and multiple doses in healthy postmenopausal women.

Cristina Castelli M, Bhaskar S, Lippman J.

Clin Ther. 2013 Jun;35(6):862-9. doi: 10.1016/j.clinthera.2013.05.001.

PMID:
23795577
[PubMed - indexed for MEDLINE]
9.
10.

Evaluation of pharmacokinetic and pharmacodynamic profiles and tolerability after single (2.5, 5, or 10 mg) and repeated (2.5, 5, or 10 mg bid for 4.5 days) oral administration of ivabradine in healthy male Korean volunteers.

Choi HY, Noh YH, Cho SH, Ghim JL, Choe S, Kim UJ, Ah Jung J, Bae KS, Lim HS.

Clin Ther. 2013 Jun;35(6):819-35. doi: 10.1016/j.clinthera.2013.04.012. Epub 2013 Jun 4.

PMID:
23755867
[PubMed - indexed for MEDLINE]
11.

Pharmacokinetic and pharmacodynamic assessments of the dipeptidyl peptidase-4 inhibitor PHX1149: double-blind, placebo-controlled, single- and multiple-dose studies in healthy subjects.

O'Farrell AM, van Vliet A, Abou Farha K, Cherrington JM, Campbell DA, Li X, Hanway D, Li J, Guler HP.

Clin Ther. 2007 Aug;29(8):1692-705.

PMID:
17919550
[PubMed - indexed for MEDLINE]
12.

Safety and clinical pharmacokinetics of nemonoxacin, a novel non-fluorinated quinolone, in healthy Chinese volunteers following single and multiple oral doses.

Guo B, Wu X, Zhang Y, Shi Y, Yu J, Cao G, Zhang J.

Clin Drug Investig. 2012 Jul 1;32(7):475-86. doi: 10.2165/11632780-000000000-00000.

PMID:
22650326
[PubMed - indexed for MEDLINE]
13.

The effect of different meal compositions on the oral bioavailability of treprostinil diolamine in healthy volunteers.

Lim A, Wang-Smith L, Kates J, Laurent A, Kumar P, Laliberte K.

J Clin Pharm Ther. 2013 Dec;38(6):450-5. doi: 10.1111/jcpt.12085. Epub 2013 Aug 8.

PMID:
23927483
[PubMed - in process]
14.

Pharmacokinetics and tolerability of multiple-dose rosuvastatin: An open-label, randomized-sequence, three-way crossover trial in healthy Chinese volunteers.

Zhang R, Li Y, Jiang X, Wang L.

Curr Ther Res Clin Exp. 2009 Oct;70(5):392-404. doi: 10.1016/j.curtheres.2009.10.004.

PMID:
24683247
[PubMed]
Free PMC Article
15.

Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension.

White RJ, Torres F, Allen R, Jerjes C, Pulido T, Yehle D, Howell M, Laliberte K, Marier JF, Tapson VF.

J Cardiovasc Pharmacol. 2013 Jun;61(6):474-81. doi: 10.1097/FJC.0b013e31828685da.

PMID:
23328389
[PubMed - indexed for MEDLINE]
16.

Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers.

Bergman AJ, Stevens C, Zhou Y, Yi B, Laethem M, De Smet M, Snyder K, Hilliard D, Tanaka W, Zeng W, Tanen M, Wang AQ, Chen L, Winchell G, Davies MJ, Ramael S, Wagner JA, Herman GA.

Clin Ther. 2006 Jan;28(1):55-72.

PMID:
16490580
[PubMed - indexed for MEDLINE]
17.

Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, follow-up study.

Vollmer T, Blight AR, Henney HR 3rd.

Clin Ther. 2009 Oct;31(10):2215-23. doi: 10.1016/j.clinthera.2009.10.007.

PMID:
19922892
[PubMed - indexed for MEDLINE]
18.
19.

Safety and pharmacokinetics of NXN-188 after single and multiple doses in five phase I, randomized, double-blind, parallel studies in healthy adult volunteers.

Vaughan D, Speed J, Medve R, Andrews JS.

Clin Ther. 2010 Jan;32(1):146-60. doi: 10.1016/j.clinthera.2010.01.006.

PMID:
20171420
[PubMed - indexed for MEDLINE]
20.

Pharmacokinetics and safety of escalating single and repeat oral doses of GW420867X, a novel non-nucleoside reverse transcriptase inhibitor.

Moore KH, Cass LM, Dallow N, Hardman TC, Jones A, Boyce M, Prince WT.

Eur J Clin Pharmacol. 2001 Jan-Feb;56(11):805-11.

PMID:
11294370
[PubMed - indexed for MEDLINE]

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