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Items: 1 to 20 of 253

1.

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells.

Huang YH, Lin MH, Wang PC, Wu YC, Chiang HL, Wang YL, Chang JH, Huang YK, Gu SY, Ho HN, Ling TY.

Mol Hum Reprod. 2014 Jun;20(6):526-37. doi: 10.1093/molehr/gau016. Epub 2014 Mar 5.

2.

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B.

Genes Dev. 2006 Mar 1;20(5):557-70.

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[Silencing hypoxia inducible factor-2α gene by small interference RNA inhibits the growth of mammosphere cells in nude mice under hypoxic microenvironment].

Qu HB, Fan YM, Han ML, Zeng N, Zhu ZK, Liu H, Xie J, Wu CY, Tang WX.

Zhonghua Yi Xue Za Zhi. 2013 Apr 16;93(15):1182-7. Chinese.

PMID:
23902893
5.

A HIF-1alpha-dependent autocrine feedback loop promotes survival of serum-deprived prostate cancer cells.

Thomas R, Kim MH.

Prostate. 2009 Feb 15;69(3):263-75. doi: 10.1002/pros.20885.

PMID:
19016246
8.

Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells.

Mimeault M, Batra SK.

J Cell Mol Med. 2013 Jan;17(1):30-54. doi: 10.1111/jcmm.12004. Epub 2013 Jan 10.

9.

Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.

Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, Axelson M, Biberfeld P, Poellinger L, Brismar K.

Clin Cancer Res. 2006 Aug 1;12(15):4506-14.

10.

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.

Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.

PLoS One. 2010 Jun 21;5(6):e11241. doi: 10.1371/journal.pone.0011241.

11.

The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor.

Liu TZ, Wang X, Bai YF, Liao HZ, Qiu SC, Yang YQ, Yan XH, Chen J, Guo HB, Zhang SZ.

Int J Biochem Cell Biol. 2014 Apr;49:8-16. doi: 10.1016/j.biocel.2014.01.007. Epub 2014 Jan 13.

PMID:
24434023
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14.

Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.

Lee SH, Lee MY, Han HJ.

Cell Prolif. 2008 Apr;41(2):230-47. doi: 10.1111/j.1365-2184.2008.00516.x.

PMID:
18336469
15.

The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion.

Koh MY, Lemos R Jr, Liu X, Powis G.

Cancer Res. 2011 Jun 1;71(11):4015-27. doi: 10.1158/0008-5472.CAN-10-4142. Epub 2011 Apr 21.

16.

The inhibitory effect of hypoxic cytotoxin on the expansion of cancer stem cells in ovarian cancer.

Nozawa-Suzuki N, Nagasawa H, Ohnishi K, Morishige K.

Biochem Biophys Res Commun. 2015 Feb 20;457(4):706-11. doi: 10.1016/j.bbrc.2015.01.053. Epub 2015 Jan 22.

PMID:
25619133
17.

Sildenafil alleviates bronchopulmonary dysplasia in neonatal rats by activating the hypoxia-inducible factor signaling pathway.

Park HS, Park JW, Kim HJ, Choi CW, Lee HJ, Kim BI, Chun YS.

Am J Respir Cell Mol Biol. 2013 Jan;48(1):105-13. doi: 10.1165/rcmb.2012-0043OC. Epub 2012 Oct 11.

PMID:
23065129
18.

Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.

Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV.

Oncogene. 2010 May 20;29(20):2938-49. doi: 10.1038/onc.2010.60. Epub 2010 Mar 8.

PMID:
20208561
19.

Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis.

Hanna C, Hubchak SC, Liang X, Rozen-Zvi B, Schumacker PT, Hayashida T, Schnaper HW.

Am J Physiol Renal Physiol. 2013 Nov 1;305(9):F1323-31. doi: 10.1152/ajprenal.00155.2013. Epub 2013 Aug 14.

20.
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