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Comparative genomics and immunoinformatics approach for the identification of vaccine candidates for enterohemorrhagic Escherichia coli O157:H7.

García-Angulo VA, Kalita A, Kalita M, Lozano L, Torres AG.

Infect Immun. 2014 May;82(5):2016-26. doi: 10.1128/IAI.01437-13. Epub 2014 Mar 4.


Exploiting the power of OMICS approaches to produce E. coli O157 vaccines.

Kalita A, Kalita M, Torres AG.

Gut Microbes. 2014;5(6):770-4. doi: 10.4161/19490976.2014.983769.


Mucosal priming of the murine immune system against enterohemorrhagic Escherichia coli O157:H7 using Lactococcus lactis expressing the type III secretion system protein EspB.

Ahmed B, Loos M, Vanrompay D, Cox E.

Vet Immunol Immunopathol. 2013 Mar 15;152(1-2):141-5. doi: 10.1016/j.vetimm.2012.09.019. Epub 2012 Sep 26.


From In silico Protein Epitope Density Prediction to Testing Escherichia coli O157:H7 Vaccine Candidates in a Murine Model of Colonization.

Tapia D, Ross BN, Kalita A, Kalita M, Hatcher CL, Muruato LA, Torres AG.

Front Cell Infect Microbiol. 2016 Aug 30;6:94. doi: 10.3389/fcimb.2016.00094. eCollection 2016.


B-cell epitope KT-12 of enterohemorrhagic Escherichia coli O157:H7: a novel peptide vaccine candidate.

Wan CS, Zhou Y, Yu Y, Peng LJ, Zhao W, Zheng XL.

Microbiol Immunol. 2011 Apr;55(4):247-53. doi: 10.1111/j.1348-0421.2011.00316.x.


Oral immunization with Lactococcus lactis-expressing EspB induces protective immune responses against Escherichia coli O157:H7 in a murine model of colonization.

Ahmed B, Loos M, Vanrompay D, Cox E.

Vaccine. 2014 Jun 30;32(31):3909-16. doi: 10.1016/j.vaccine.2014.05.054. Epub 2014 May 28.


Vaccination with DNA Encoding Truncated Enterohemorrhagic Escherichia coli (EHEC) Factor for Adherence-1 Gene (efa-1') Confers Protective Immunity to Mice Infected with E. coli O157:H7.

Riquelme-Neira R, Rivera A, Sáez D, Fernández P, Osorio G, del Canto F, Salazar JC, Vidal RM, Oñate A.

Front Cell Infect Microbiol. 2016 Jan 20;5:104. doi: 10.3389/fcimb.2015.00104. eCollection 2015.


Adhesion and colonization of enterohemorrhagic Escherichia coli O157:H7 in cecum of mice.

Nagano K, Taguchi K, Hara T, Yokoyama S, Kawada K, Mori H.

Microbiol Immunol. 2003;47(2):125-32.


Oral immunization with attenuated Salmonella vaccine expressing Escherichia coli O157:H7 intimin gamma triggers both systemic and mucosal humoral immunity in mice.

Oliveira AF, Cardoso SA, Almeida FB, de Oliveira LL, Pitondo-Silva A, Soares SG, Hanna ES.

Microbiol Immunol. 2012 Aug;56(8):513-22. doi: 10.1111/j.1348-0421.2012.00477.x.


Towards an attenuated enterohemorrhagic Escherichia coli O157:H7 vaccine characterized by a deleted ler gene and containing apathogenic Shiga toxins.

Liu J, Sun Y, Feng S, Zhu L, Guo X, Qi C.

Vaccine. 2009 Oct 9;27(43):5929-35. doi: 10.1016/j.vaccine.2009.07.097. Epub 2009 Aug 12.


Optimizing the Protection of Cattle against Escherichia coli O157:H7 Colonization through Immunization with Different Combinations of H7 Flagellin, Tir, Intimin-531 or EspA.

McNeilly TN, Mitchell MC, Corbishley A, Nath M, Simmonds H, McAteer SP, Mahajan A, Low JC, Smith DG, Huntley JF, Gally DL.

PLoS One. 2015 May 28;10(5):e0128391. doi: 10.1371/journal.pone.0128391. eCollection 2015.


Cross reactivity of enterohemorrhagic Escherichia coli O157:H7-specific sera with non-O157 serotypes.

Asper DJ, Sekirov I, Finlay BB, Rogan D, Potter AA.

Vaccine. 2007 Nov 28;25(49):8262-9. Epub 2007 Oct 12.


Novel fusion protein protects against adherence and toxicity of enterohemorrhagic Escherichia coli O157:H7 in mice.

Gao X, Cai K, Li T, Wang Q, Hou X, Tian R, Liu H, Tu W, Xiao L, Fang L, Luo S, Liu Y, Wang H.

Vaccine. 2011 Sep 2;29(38):6656-63. doi: 10.1016/j.vaccine.2011.06.106. Epub 2011 Jul 8.


Comparative genomics of enterohemorrhagic Escherichia coli O145:H28 demonstrates a common evolutionary lineage with Escherichia coli O157:H7.

Cooper KK, Mandrell RE, Louie JW, Korlach J, Clark TA, Parker CT, Huynh S, Chain PS, Ahmed S, Carter MQ.

BMC Genomics. 2014 Jan 10;15:17. doi: 10.1186/1471-2164-15-17.


Use of immunoglobulin enriched bovine colostrum against oral challenge with enterohaemorrhagic Escherichia coli O157:H7 in mice.

Funatogawa K, Ide T, Kirikae F, Saruta K, Nakano M, Kirikae T.

Microbiol Immunol. 2002;46(11):761-6.


Vaccination of attenuated EIS-producing Salmonella induces protective immunity against enterohemorrhagic Escherichia coli in mice.

Gu J, Ning Y, Wang H, Xiao D, Tang B, Luo P, Cheng Y, Jiang M, Li N, Zou Q, Mao X.

Vaccine. 2011 Oct 6;29(43):7395-403. doi: 10.1016/j.vaccine.2011.07.069. Epub 2011 Jul 30.


Enterohemorrhagic Escherichia coli trivalent recombinant vaccine containing EspA, intimin and Stx2 induces strong humoral immune response and confers protection in mice.

Gu J, Liu Y, Yu S, Wang H, Wang Q, Yi Y, Zhu F, Yu XJ, Zou Q, Mao X.

Microbes Infect. 2009 Sep;11(10-11):835-41. doi: 10.1016/j.micinf.2009.04.024. Epub 2009 May 7.


[Construction and immunization of a enterohemorrhagic Escherichia coli O157 attenuated].

Liu J, Sun Y, Feng SZ.

Sheng Wu Gong Cheng Xue Bao. 2007 Mar;23(2):211-7. Chinese.


Immunogenicity of recombinant porcine attaching and effacing-associated protein compared with intimin fragment in Escherichia coli O157:H7-infected mice.

Li T, Han R, Wang Q, Wang S, Fang H, Li Z, Tu W, Wang D, Wang H.

Foodborne Pathog Dis. 2013 Dec;10(12):1016-22. doi: 10.1089/fpd.2013.1496. Epub 2013 Oct 5.

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