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Items: 1 to 20 of 101

1.

The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death.

Chen HM, Zhu BZ, Chen RJ, Wang BJ, Wang YJ.

PLoS One. 2014 Feb 26;9(2):e89483. doi: 10.1371/journal.pone.0089483. eCollection 2014.

2.

ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone.

Chen HM, Lee YH, Wang YJ.

Chem Res Toxicol. 2015 Mar 16;28(3):339-50. doi: 10.1021/tx500487w. Epub 2015 Feb 2. Review.

PMID:
25608107
3.
4.
5.

Dihydrolipoic acid inhibits tetrachlorohydroquinone-induced tumor promotion through prevention of oxidative damage.

Wang YJ, Yang MC, Pan MH.

Food Chem Toxicol. 2008 Dec;46(12):3739-48. doi: 10.1016/j.fct.2008.09.064. Epub 2008 Oct 7.

PMID:
18951944
6.

Bcl-2 overexpression inhibits tetrachlorohydroquinone-induced apoptosis in NIH3T3 cells: a possible mechanism for tumor promotion.

Lin YP, Zhu BZ, Yang MC, Frei B, Pan MH, Lin JK, Wang YJ.

Mol Carcinog. 2004 May;40(1):24-33.

PMID:
15108327
7.

Cytotoxic effects of pentachlorophenol (PCP) and its metabolite tetrachlorohydroquinone (TCHQ) on liver cells are modulated by antioxidants.

Pietsch C, Hollender J, Dorusch F, Burkhardt-Holm P.

Cell Biol Toxicol. 2014 Aug;30(4):233-52. doi: 10.1007/s10565-014-9283-4. Epub 2014 Jul 5.

PMID:
24996998
8.
9.

Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol.

Wang YJ, Ho YS, Chu SW, Lien HJ, Liu TH, Lin JK.

Chem Biol Interact. 1997 Jun 6;105(1):1-16. Erratum in: Chem Biol Interact 1997 Aug 29;106(1):87.

PMID:
9233372
10.

Skin tumor-promoting potential and systemic effects of pentachlorophenol and its major metabolite tetrachlorohydroquinone in CD-1 Mice.

Chang WC, Jeng JH, Shieh CC, Tsai YC, Ho YS, Guo HR, Liu HI, Lee CC, Ho SY, Wang YJ.

Mol Carcinog. 2003 Apr;36(4):161-70.

PMID:
12669308
11.

Role of active oxygen species in DNA damage by pentachlorophenol metabolites.

Naito S, Ono Y, Somiya I, Inoue S, Ito K, Yamamoto K, Kawanishi S.

Mutat Res. 1994 Oct 1;310(1):79-88.

PMID:
7523887
12.

Characterization of TCHQ-induced genotoxicity and mutagenesis using the pSP189 shuttle vector in mammalian cells.

Wang J, Yu S, Jiao S, Lv X, Ma M, Zhu BZ, Du Y.

Mutat Res. 2012 Jan 3;729(1-2):16-23. doi: 10.1016/j.mrfmmm.2011.08.010. Epub 2011 Sep 8.

PMID:
21924276
13.

Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium.

Kim J, Kim SH, Johnson VJ, Sharma RP.

Environ Toxicol Chem. 2005 Dec;24(12):3069-77.

PMID:
16445087
14.

Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways.

Lu TH, Tseng TJ, Su CC, Tang FC, Yen CC, Liu YY, Yang CY, Wu CC, Chen KL, Hung DZ, Chen YW.

Toxicol Lett. 2014 Jan 3;224(1):130-40. doi: 10.1016/j.toxlet.2013.10.013. Epub 2013 Oct 21.

PMID:
24157283
16.

Differences in genotoxicity of H(2)O(2) and tetrachlorohydroquinone in human fibroblasts.

Purschke M, Jacobi H, Witte I.

Mutat Res. 2002 Jan 15;513(1-2):159-67.

PMID:
11719101
17.

Effects of hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone on serum thyroid hormone levels in rats.

van Raaij JA, van den Berg KJ, Engel R, Bragt PC, Notten WR.

Toxicology. 1991 Mar 25;67(1):107-16.

PMID:
2017761
19.
20.

In vivo levels of chlorinated hydroquinones in a pentachlorophenol-degrading bacterium.

McCarthy DL, Claude AA, Copley SD.

Appl Environ Microbiol. 1997 May;63(5):1883-8.

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