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Results: 1 to 20 of 84

1.

Loss of Trabid, a new negative regulator of the drosophila immune-deficiency pathway at the level of TAK1, reduces life span.

Fernando MD, Kounatidis I, Ligoxygakis P.

PLoS Genet. 2014 Feb 20;10(2):e1004117. doi: 10.1371/journal.pgen.1004117. eCollection 2014 Feb.

PMID:
24586180
[PubMed - in process]
Free PMC Article
2.

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

Tran H, Hamada F, Schwarz-Romond T, Bienz M.

Genes Dev. 2008 Feb 15;22(4):528-42. doi: 10.1101/gad.463208.

PMID:
18281465
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation.

Mao R, Fan Y, Mou Y, Zhang H, Fu S, Yang J.

Cell Signal. 2011 Jan;23(1):222-7. doi: 10.1016/j.cellsig.2010.09.006. Epub 2010 Sep 16.

PMID:
20837137
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL.

Walsh MC, Kim GK, Maurizio PL, Molnar EE, Choi Y.

PLoS One. 2008;3(12):e4064. doi: 10.1371/journal.pone.0004064. Epub 2008 Dec 29.

PMID:
19112497
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.

Sorrentino A, Thakur N, Grimsby S, Marcusson A, von Bulow V, Schuster N, Zhang S, Heldin CH, Landström M.

Nat Cell Biol. 2008 Oct;10(10):1199-207. doi: 10.1038/ncb1780. Epub 2008 Aug 31.

PMID:
18758450
[PubMed - indexed for MEDLINE]
6.

β-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation.

Cui W, Xiao N, Xiao H, Zhou H, Yu M, Gu J, Li X.

Mol Cell Biol. 2012 Oct;32(19):3990-4000. doi: 10.1128/MCB.00722-12. Epub 2012 Jul 30.

PMID:
22851693
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome.

Engel E, Viargues P, Mortier M, Taillebourg E, Couté Y, Thevenon D, Fauvarque MO.

Cell Commun Signal. 2014 Jul 16;12(1):41. doi: 10.1186/PREACCEPT-1588328929121802.

PMID:
25027767
[PubMed - in process]
Free PMC Article
9.

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.

Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L, Chen ZJ.

Mol Cell. 2004 Aug 27;15(4):535-48.

PMID:
15327770
[PubMed - indexed for MEDLINE]
Free Article
10.

Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation.

Fan Y, Yu Y, Shi Y, Sun W, Xie M, Ge N, Mao R, Chang A, Xu G, Schneider MD, Zhang H, Fu S, Qin J, Yang J.

J Biol Chem. 2010 Feb 19;285(8):5347-60. doi: 10.1074/jbc.M109.076976. Epub 2009 Dec 28.

PMID:
20038579
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs.

Ori D, Kato H, Sanjo H, Tartey S, Mino T, Akira S, Takeuchi O.

J Immunol. 2013 Apr 15;190(8):4037-45. doi: 10.4049/jimmunol.1300173. Epub 2013 Mar 15.

PMID:
23509369
[PubMed - indexed for MEDLINE]
Free Article
12.

Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.

Ray DM, Rogers BA, Sunman JA, Akiyama SK, Olden K, Roberts JD.

Biochem Cell Biol. 2010 Dec;88(6):947-56. doi: 10.1139/O10-148.

PMID:
21102657
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The Drosophila ubiquitin-specific protease dUSP36/Scny targets IMD to prevent constitutive immune signaling.

Thevenon D, Engel E, Avet-Rochex A, Gottar M, Bergeret E, Tricoire H, Benaud C, Baudier J, Taillebourg E, Fauvarque MO.

Cell Host Microbe. 2009 Oct 22;6(4):309-20. doi: 10.1016/j.chom.2009.09.007.

PMID:
19837371
[PubMed - indexed for MEDLINE]
Free Article
14.

TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.

Morlon A, Munnich A, Smahi A.

Hum Mol Genet. 2005 Dec 1;14(23):3751-7. Epub 2005 Oct 26.

PMID:
16251197
[PubMed - indexed for MEDLINE]
Free Article
15.

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation.

Zhang L, Ding X, Cui J, Xu H, Chen J, Gong YN, Hu L, Zhou Y, Ge J, Lu Q, Liu L, Chen S, Shao F.

Nature. 2011 Dec 11;481(7380):204-8. doi: 10.1038/nature10690.

PMID:
22158122
[PubMed - indexed for MEDLINE]
16.

Iap2 is required for a sustained response in the Drosophila Imd pathway.

Valanne S, Kleino A, Myllymäki H, Vuoristo J, Rämet M.

Dev Comp Immunol. 2007;31(10):991-1001. Epub 2007 Feb 15.

PMID:
17343912
[PubMed - indexed for MEDLINE]
17.

The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway.

Thiefes A, Wolf A, Doerrie A, Grassl GA, Matsumoto K, Autenrieth I, Bohn E, Sakurai H, Niedenthal R, Resch K, Kracht M.

EMBO Rep. 2006 Aug;7(8):838-44. Epub 2006 Jul 14.

PMID:
16845370
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila.

Tsuda M, Langmann C, Harden N, Aigaki T.

EMBO Rep. 2005 Nov;6(11):1082-7. Epub 2005 Sep 23.

PMID:
16179944
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter protein.

Yu Q, Minoda Y, Yoshida R, Yoshida H, Iha H, Kobayashi T, Yoshimura A, Takaesu G.

Biochem Biophys Res Commun. 2008 Jan 4;365(1):189-94. Epub 2007 Nov 5.

PMID:
17986383
[PubMed - indexed for MEDLINE]
20.

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

Wang Y, Huang G, Vogel P, Neale G, Reizis B, Chi H.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):E343-52. doi: 10.1073/pnas.1115635109. Epub 2012 Jan 23.

PMID:
22308391
[PubMed - indexed for MEDLINE]
Free PMC Article

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