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Items: 1 to 20 of 95

1.

Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury.

Piccioni A, Gaetani E, Palladino M, Gatto I, Smith RC, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R.

Gene Ther. 2014 Apr;21(4):413-21. doi: 10.1038/gt.2014.13. Epub 2014 Feb 27.

PMID:
24572787
2.

Sonic hedgehog therapy in a mouse model of age-associated impairment of skeletal muscle regeneration.

Piccioni A, Gaetani E, Neri V, Gatto I, Palladino M, Silver M, Smith RC, Giarretta I, Pola E, Hlatky L, Pola R.

J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):245-52. doi: 10.1093/gerona/glt076. Epub 2013 Jun 18.

3.

Matrix metalloproteinase-9 inhibition improves proliferation and engraftment of myogenic cells in dystrophic muscle of mdx mice.

Hindi SM, Shin J, Ogura Y, Li H, Kumar A.

PLoS One. 2013 Aug 15;8(8):e72121. doi: 10.1371/journal.pone.0072121. eCollection 2013.

4.

Sonic hedgehog regulates angiogenesis and myogenesis during post-natal skeletal muscle regeneration.

Straface G, Aprahamian T, Flex A, Gaetani E, Biscetti F, Smith RC, Pecorini G, Pola E, Angelini F, Stigliano E, Castellot JJ Jr, Losordo DW, Pola R.

J Cell Mol Med. 2009 Aug;13(8B):2424-35. doi: 10.1111/j.1582-4934.2008.00440.x. Epub 2008 Jul 26.

5.

MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.

Bobadilla M, Sáinz N, Rodriguez JA, Abizanda G, Orbe J, de Martino A, García Verdugo JM, Páramo JA, Prósper F, Pérez-Ruiz A.

Stem Cells. 2014 Feb;32(2):447-61. doi: 10.1002/stem.1553.

6.

Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia.

Pola R, Ling LE, Aprahamian TR, Barban E, Bosch-Marce M, Curry C, Corbley M, Kearney M, Isner JM, Losordo DW.

Circulation. 2003 Jul 29;108(4):479-85. Epub 2003 Jul 14.

7.

microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice.

Liu N, Williams AH, Maxeiner JM, Bezprozvannaya S, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN.

J Clin Invest. 2012 Jun;122(6):2054-65. doi: 10.1172/JCI62656. Epub 2012 May 1.

8.

IFN-γ promotes muscle damage in the mdx mouse model of Duchenne muscular dystrophy by suppressing M2 macrophage activation and inhibiting muscle cell proliferation.

Villalta SA, Deng B, Rinaldi C, Wehling-Henricks M, Tidball JG.

J Immunol. 2011 Nov 15;187(10):5419-28. doi: 10.4049/jimmunol.1101267. Epub 2011 Oct 17.

9.

Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice.

Tang Y, Reay DP, Salay MN, Mi MY, Clemens PR, Guttridge DC, Robbins PD, Huard J, Wang B.

Gene Ther. 2010 Dec;17(12):1476-83. doi: 10.1038/gt.2010.110. Epub 2010 Aug 19.

10.

Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells.

Luz MA, Marques MJ, Santo Neto H.

Braz J Med Biol Res. 2002 Jun;35(6):691-5.

11.

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy.

Wehling-Henricks M, Sokolow S, Lee JJ, Myung KH, Villalta SA, Tidball JG.

Hum Mol Genet. 2008 Aug 1;17(15):2280-92. doi: 10.1093/hmg/ddn129. Epub 2008 Apr 21.

12.

Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy.

Morales MG, Gutierrez J, Cabello-Verrugio C, Cabrera D, Lipson KE, Goldschmeding R, Brandan E.

Hum Mol Genet. 2013 Dec 15;22(24):4938-51. doi: 10.1093/hmg/ddt352. Epub 2013 Jul 30.

13.

Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice.

Jørgensen LH, Jensen CH, Wewer UM, Schrøder HD.

Am J Pathol. 2007 Nov;171(5):1599-607.

14.

Hedgehog can drive terminal differentiation of amniote slow skeletal muscle.

Li X, Blagden CS, Bildsoe H, Bonnin MA, Duprez D, Hughes SM.

BMC Dev Biol. 2004 Jul 6;4:9.

15.

Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy.

Li H, Mittal A, Makonchuk DY, Bhatnagar S, Kumar A.

Hum Mol Genet. 2009 Jul 15;18(14):2584-98. doi: 10.1093/hmg/ddp191. Epub 2009 Apr 28.

16.

Combined therapy with sonic hedgehog gene transfer and bone marrow-derived endothelial progenitor cells enhances angiogenesis and myogenesis in the ischemic skeletal muscle.

Palladino M, Gatto I, Neri V, Stigliano E, Smith RC, Pola E, Straino S, Gaetani E, Capogrossi M, Leone G, Hlatky L, Pola R.

J Vasc Res. 2012;49(5):425-31. doi: 10.1159/000337921. Epub 2012 Jun 22.

PMID:
22739401
17.

Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy.

Kimura E, Han JJ, Li S, Fall B, Ra J, Haraguchi M, Tapscott SJ, Chamberlain JS.

Hum Mol Genet. 2008 Aug 15;17(16):2507-17. doi: 10.1093/hmg/ddn151. Epub 2008 May 29.

18.

Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle.

Deasy BM, Feduska JM, Payne TR, Li Y, Ambrosio F, Huard J.

Mol Ther. 2009 Oct;17(10):1788-98. doi: 10.1038/mt.2009.136. Epub 2009 Jul 14.

19.

Angiogenic impairment of the vascular endothelium: a novel mechanism and potential therapeutic target in muscular dystrophy.

Palladino M, Gatto I, Neri V, Straino S, Smith RC, Silver M, Gaetani E, Marcantoni M, Giarretta I, Stigliano E, Capogrossi M, Hlatky L, Landolfi R, Pola R.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2867-76. doi: 10.1161/ATVBAHA.112.301172. Epub 2013 Sep 26.

20.

The myogenic factor Myf5 supports efficient skeletal muscle regeneration by enabling transient myoblast amplification.

Ustanina S, Carvajal J, Rigby P, Braun T.

Stem Cells. 2007 Aug;25(8):2006-16. Epub 2007 May 10.

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