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Results: 1 to 20 of 108

Related Citations for PubMed (Select 24567327)

1.

Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ.

J Biol Chem. 2014 Apr 11;289(15):10727-37. doi: 10.1074/jbc.M113.524520. Epub 2014 Feb 24.

PMID:
24567327
2.

Aggregation of α-synuclein is kinetically controlled by intramolecular diffusion.

Ahmad B, Chen Y, Lapidus LJ.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2336-41. doi: 10.1073/pnas.1109526109. Epub 2012 Jan 27.

3.
4.

Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.

Sinha S, Lopes DH, Du Z, Pang ES, Shanmugam A, Lomakin A, Talbiersky P, Tennstaedt A, McDaniel K, Bakshi R, Kuo PY, Ehrmann M, Benedek GB, Loo JA, Klärner FG, Schrader T, Wang C, Bitan G.

J Am Chem Soc. 2011 Oct 26;133(42):16958-69. doi: 10.1021/ja206279b. Epub 2011 Sep 29.

5.

Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation.

Binolfi A, Lamberto GR, Duran R, Quintanar L, Bertoncini CW, Souza JM, Cerveñansky C, Zweckstetter M, Griesinger C, Fernández CO.

J Am Chem Soc. 2008 Sep 3;130(35):11801-12. doi: 10.1021/ja803494v. Epub 2008 Aug 9.

PMID:
18693689
6.

Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein.

Ducas VC, Rhoades E.

PLoS One. 2014 Jan 28;9(1):e86983. doi: 10.1371/journal.pone.0086983. eCollection 2014.

7.

Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.

Sinha S, Du Z, Maiti P, Klärner FG, Schrader T, Wang C, Bitan G.

ACS Chem Neurosci. 2012 Jun 20;3(6):451-8. doi: 10.1021/cn200133x. Epub 2012 Mar 7.

8.

Copper(II)-induced self-oligomerization of alpha-synuclein.

Paik SR, Shin HJ, Lee JH, Chang CS, Kim J.

Biochem J. 1999 Jun 15;340 ( Pt 3):821-8.

9.

Curcumin prevents aggregation in α-synuclein by increasing reconfiguration rate.

Ahmad B, Lapidus LJ.

J Biol Chem. 2012 Mar 16;287(12):9193-9. doi: 10.1074/jbc.M111.325548. Epub 2012 Jan 20.

10.

Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.

Högen T, Levin J, Schmidt F, Caruana M, Vassallo N, Kretzschmar H, Bötzel K, Kamp F, Giese A.

Biophys J. 2012 Apr 4;102(7):1646-55. doi: 10.1016/j.bpj.2012.01.059. Epub 2012 Apr 3.

11.

The early events of alpha-synuclein oligomerization revealed by photo-induced cross-linking.

Li HT, Lin XJ, Xie YY, Hu HY.

Protein Pept Lett. 2006;13(4):385-90.

PMID:
16712515
12.

Covalent α-synuclein dimers: chemico-physical and aggregation properties.

Pivato M, De Franceschi G, Tosatto L, Frare E, Kumar D, Aioanei D, Brucale M, Tessari I, Bisaglia M, Samori B, de Laureto PP, Bubacco L.

PLoS One. 2012;7(12):e50027. doi: 10.1371/journal.pone.0050027. Epub 2012 Dec 13.

13.

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

Fernández CO, Hoyer W, Zweckstetter M, Jares-Erijman EA, Subramaniam V, Griesinger C, Jovin TM.

EMBO J. 2004 May 19;23(10):2039-46. Epub 2004 Apr 22.

14.

Characterization of inhibitor-bound alpha-synuclein dimer: role of alpha-synuclein N-terminal region in dimerization and inhibitor binding.

Yamaguchi Y, Masuda M, Sasakawa H, Nonaka T, Hanashima S, Hisanaga S, Kato K, Hasegawa M.

J Mol Biol. 2010 Jan 22;395(3):445-56. doi: 10.1016/j.jmb.2009.10.068. Epub 2009 Nov 3.

PMID:
19895818
15.

A relationship between the transient structure in the monomeric state and the aggregation propensities of α-synuclein and β-synuclein.

Allison JR, Rivers RC, Christodoulou JC, Vendruscolo M, Dobson CM.

Biochemistry. 2014 Nov 25;53(46):7170-83. doi: 10.1021/bi5009326. Epub 2014 Nov 12.

PMID:
25389903
16.

Multiparametric fluorescence detection of early stages in the amyloid protein aggregation of pyrene-labeled alpha-synuclein.

Thirunavukkuarasu S, Jares-Erijman EA, Jovin TM.

J Mol Biol. 2008 May 16;378(5):1064-73. doi: 10.1016/j.jmb.2008.03.034. Epub 2008 Mar 26.

PMID:
18433772
17.

Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.

De Genst EJ, Guilliams T, Wellens J, O'Day EM, Waudby CA, Meehan S, Dumoulin M, Hsu ST, Cremades N, Verschueren KH, Pardon E, Wyns L, Steyaert J, Christodoulou J, Dobson CM.

J Mol Biol. 2010 Sep 17;402(2):326-43. doi: 10.1016/j.jmb.2010.07.001. Epub 2010 Jul 8.

PMID:
20620148
18.

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.

Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM.

Neurotherapeutics. 2012 Apr;9(2):464-76. doi: 10.1007/s13311-012-0105-1. Erratum in: Neurotherapeutics. 2012 Apr;9(2):486. Lakshmanan, Ravi [corrected to Lakshmanan, Rajeswari].

19.

Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation.

Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR.

J Am Chem Soc. 2012 Mar 28;134(12):5468-71. doi: 10.1021/ja300094r. Epub 2012 Mar 14.

20.

Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies.

Shaltiel-Karyo R, Frenkel-Pinter M, Egoz-Matia N, Frydman-Marom A, Shalev DE, Segal D, Gazit E.

PLoS One. 2010 Nov 10;5(11):e13863. doi: 10.1371/journal.pone.0013863.

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