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Results: 1 to 20 of 118

1.

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels.

Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD.

Biochem Pharmacol. 2014 May 15;89(2):276-86. doi: 10.1016/j.bcp.2014.02.008. Epub 2014 Feb 19.

PMID:
24561180
[PubMed - indexed for MEDLINE]
2.

SNX-325, a novel calcium antagonist from the spider Segestria florentina.

Newcomb R, Palma A, Fox J, Gaur S, Lau K, Chung D, Cong R, Bell JR, Horne B, Nadasdi L, et al.

Biochemistry. 1995 Jul 4;34(26):8341-7.

PMID:
7541240
[PubMed - indexed for MEDLINE]
3.

Characterization of voltage-dependent calcium channel blocking peptides from the venom of the tarantula Grammostola rosea.

Ono S, Kimura T, Kubo T.

Toxicon. 2011 Sep 1;58(3):265-76. doi: 10.1016/j.toxicon.2011.06.006. Epub 2011 Jun 28.

PMID:
21740921
[PubMed - indexed for MEDLINE]
4.

Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.

Newcomb R, Szoke B, Palma A, Wang G, Chen Xh, Hopkins W, Cong R, Miller J, Urge L, Tarczy-Hornoch K, Loo JA, Dooley DJ, Nadasdi L, Tsien RW, Lemos J, Miljanich G.

Biochemistry. 1998 Nov 3;37(44):15353-62.

PMID:
9799496
[PubMed - indexed for MEDLINE]
5.

A novel family of insect-selective peptide neurotoxins targeting insect large-conductance calcium-activated K+ channels isolated from the venom of the theraphosid spider Eucratoscelus constrictus.

Windley MJ, Escoubas P, Valenzuela SM, Nicholson GM.

Mol Pharmacol. 2011 Jul;80(1):1-13. doi: 10.1124/mol.110.070540. Epub 2011 Mar 29.

PMID:
21447641
[PubMed - indexed for MEDLINE]
Free Article
6.

Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.

Escoubas P, De Weille JR, Lecoq A, Diochot S, Waldmann R, Champigny G, Moinier D, Ménez A, Lazdunski M.

J Biol Chem. 2000 Aug 18;275(33):25116-21.

PMID:
10829030
[PubMed - indexed for MEDLINE]
Free Article
7.

Inhibition of neuronal calcium channels by a novel peptide spider toxin, DW13.3.

Sutton KG, Siok C, Stea A, Zamponi GW, Heck SD, Volkmann RA, Ahlijanian MK, Snutch TP.

Mol Pharmacol. 1998 Aug;54(2):407-18.

PMID:
9687583
[PubMed - indexed for MEDLINE]
Free Article
8.

Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels.

Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ.

Mol Pharmacol. 2010 Feb;77(2):139-48. doi: 10.1124/mol.109.058834. Epub 2009 Nov 5.

PMID:
19892914
[PubMed - indexed for MEDLINE]
Free Article
9.

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels.

Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP.

Biochemistry. 2013 Oct 22;52(42):7439-48. doi: 10.1021/bi4006418. Epub 2013 Oct 7.

PMID:
24044413
[PubMed - indexed for MEDLINE]
10.

Omega-grammotoxin SIA blocks multiple, voltage-gated, Ca2+ channel subtypes in cultured rat hippocampal neurons.

Piser TM, Lampe RA, Keith RA, Thayer SA.

Mol Pharmacol. 1995 Jul;48(1):131-9.

PMID:
7623767
[PubMed - indexed for MEDLINE]
11.

Inhibition of insect calcium channels by huwentoxin-V, a neurotoxin from Chinese tarantula Ornithoctonus huwena venom.

Deng M, Luo X, Meng E, Xiao Y, Liang S.

Eur J Pharmacol. 2008 Mar 17;582(1-3):12-6. doi: 10.1016/j.ejphar.2007.12.014. Epub 2007 Dec 27.

PMID:
18234186
[PubMed - indexed for MEDLINE]
12.

Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.

Bosmans F, Rash L, Zhu S, Diochot S, Lazdunski M, Escoubas P, Tytgat J.

Mol Pharmacol. 2006 Feb;69(2):419-29. Epub 2005 Nov 2.

PMID:
16267209
[PubMed - indexed for MEDLINE]
Free Article
13.

Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor.

Deng M, Luo X, Jiang L, Chen H, Wang J, He H, Liang S.

Toxicon. 2013 Sep;71:57-65. doi: 10.1016/j.toxicon.2013.05.015. Epub 2013 May 29.

PMID:
23726857
[PubMed - indexed for MEDLINE]
14.

Synthesis and characterization of delta-atracotoxin-Ar1a, the lethal neurotoxin from venom of the Sydney funnel-web spider (Atrax robustus).

Alewood D, Birinyi-Strachan LC, Pallaghy PK, Norton RS, Nicholson GM, Alewood PF.

Biochemistry. 2003 Nov 11;42(44):12933-40.

PMID:
14596608
[PubMed - indexed for MEDLINE]
15.

Jingzhaotoxin-I, a novel spider neurotoxin preferentially inhibiting cardiac sodium channel inactivation.

Xiao Y, Tang J, Hu W, Xie J, Maertens C, Tytgat J, Liang S.

J Biol Chem. 2005 Apr 1;280(13):12069-76. Epub 2004 Nov 17.

PMID:
15548530
[PubMed - indexed for MEDLINE]
Free Article
16.

ω-Phonetoxin-IIA: a calcium channel blocker from the spider Phoneutria nigriventer.

Cassola AC, Jaffe H, Fales HM, Afeche SC, Magnoli F, Cipolla-Neto J.

Pflugers Arch. 1998 Jul;436(4):545-52.

PMID:
9683727
[PubMed - indexed for MEDLINE]
17.

CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons.

Kubista H, Mafra RA, Chong Y, Nicholson GM, Beirão PS, Cruz JS, Boehm S, Nentwig W, Kuhn-Nentwig L.

Neuropharmacology. 2007 Jun;52(8):1650-62. Epub 2007 Apr 4.

PMID:
17517422
[PubMed - indexed for MEDLINE]
18.

Two tarantula peptides inhibit activation of multiple sodium channels.

Middleton RE, Warren VA, Kraus RL, Hwang JC, Liu CJ, Dai G, Brochu RM, Kohler MG, Gao YD, Garsky VM, Bogusky MJ, Mehl JT, Cohen CJ, Smith MM.

Biochemistry. 2002 Dec 17;41(50):14734-47.

PMID:
12475222
[PubMed - indexed for MEDLINE]
19.

A novel peptide from funnel web spider venom, omega-Aga-TK, selectively blocks, P-type calcium channels.

Teramoto T, Kuwada M, Niidome T, Sawada K, Nishizawa Y, Katayama K.

Biochem Biophys Res Commun. 1993 Oct 15;196(1):134-40.

PMID:
8216284
[PubMed - indexed for MEDLINE]
20.

Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.

Redaelli E, Cassulini RR, Silva DF, Clement H, Schiavon E, Zamudio FZ, Odell G, Arcangeli A, Clare JJ, Alagón A, de la Vega RC, Possani LD, Wanke E.

J Biol Chem. 2010 Feb 5;285(6):4130-42. doi: 10.1074/jbc.M109.054718. Epub 2009 Dec 2. Erratum in: J Biol Chem. 2010 Apr 23;285(17):13314.

PMID:
19955179
[PubMed - indexed for MEDLINE]
Free PMC Article

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