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Generation of mastitis resistance in cows by targeting human lysozyme gene to β-casein locus using zinc-finger nucleases.

Liu X, Wang Y, Tian Y, Yu Y, Gao M, Hu G, Su F, Pan S, Luo Y, Guo Z, Quan F, Zhang Y.

Proc Biol Sci. 2014 Feb 19;281(1780):20133368. doi: 10.1098/rspb.2013.3368. Print 2014 Apr 7.


Zinc-finger nickase-mediated insertion of the lysostaphin gene into the beta-casein locus in cloned cows.

Liu X, Wang Y, Guo W, Chang B, Liu J, Guo Z, Quan F, Zhang Y.

Nat Commun. 2013;4:2565. doi: 10.1038/ncomms3565.


Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

Moehle EA, Rock JM, Lee YL, Jouvenot Y, DeKelver RC, Gregory PD, Urnov FD, Holmes MC.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3055-60. Epub 2007 Feb 20. Erratum in: Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6090. Moehle, E A [corrected to Moehle, Erica A]; Rock, J M [corrected to Rock, Jeremy M]; Lee, Y L [corrected to Lee, Ya-Li]; Jouvenot, Y [corrected to Jouvenot, Yann]; Dekelver, R C [corrected to DeKelver, Russell C]; Gregory, P D [corrected to Gregory, Philip D]; Urnov, F D [corrected to Urnov, Fyodor D]; Holmes, M C [corrected to Holmes, Michael C].


[The ht-PAm cDNA knock-in the goat beta-casein gene locus].

Shen W, Yang ZT, Tian LY, Wu XJ, Chen H, Huang PT, Deng JX.

Sheng Wu Gong Cheng Xue Bao. 2004 May;20(3):361-5. Chinese.


[Targeted exogenous EGFP gene editing in caprine fetus fibroblasts by zinc-finger nucleases].

Yuan Y, Yu B, Song S, Zhou F, Zhang L, Gu Y, Yu M, Cheng Y.

Sheng Wu Gong Cheng Xue Bao. 2013 Nov;29(11):1573-80. Chinese.


Genetically enhanced cows resist intramammary Staphylococcus aureus infection.

Wall RJ, Powell AM, Paape MJ, Kerr DE, Bannerman DD, Pursel VG, Wells KD, Talbot N, Hawk HW.

Nat Biotechnol. 2005 Apr;23(4):445-51. Epub 2005 Apr 3. Erratum in: Nat Biotechnol. 2005 Jul;23(7):897.


Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases.

Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng X, Gregory PD, Schwinzer R, Cost GJ, Niemann H.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12013-7. doi: 10.1073/pnas.1106422108. Epub 2011 Jul 5. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):15010.


Targeting the exogenous htPAm gene on goat somatic cell beta-casein locus for transgenic goat production.

Shen W, Lan G, Yang X, Li L, Min L, Yang Z, Tian L, Wu X, Sun Y, Chen H, Tan J, Deng J, Pan Q.

Mol Reprod Dev. 2007 Apr;74(4):428-34.


Simultaneous screening and validation of effective zinc finger nucleases in yeast.

Wang L, Lin J, Zhang T, Xu K, Ren C, Zhang Z.

PLoS One. 2013 May 31;8(5):e64687. doi: 10.1371/journal.pone.0064687. Print 2013.


High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases.

Zhang F, Maeder ML, Unger-Wallace E, Hoshaw JP, Reyon D, Christian M, Li X, Pierick CJ, Dobbs D, Peterson T, Joung JK, Voytas DF.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):12028-33. doi: 10.1073/pnas.0914991107. Epub 2010 May 27.


Targeting DNA to a previously integrated transgenic locus using zinc finger nucleases.

Strange TL, Petolino JF.

Methods Mol Biol. 2012;847:391-7. doi: 10.1007/978-1-61779-558-9_31.


Transgenic modification of cows milk for value-added processing.

Zuelke KA.

Reprod Fertil Dev. 1998;10(7-8):671-6. Review.


Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK.

PLoS One. 2009;4(2):e4348. doi: 10.1371/journal.pone.0004348. Epub 2009 Feb 9.


Cloned transgenic cattle produce milk with higher levels of beta-casein and kappa-casein.

Brophy B, Smolenski G, Wheeler T, Wells D, L'Huillier P, Laible G.

Nat Biotechnol. 2003 Feb;21(2):157-62. Epub 2003 Jan 27.


Creating designed zinc-finger nucleases with minimal cytotoxicity.

Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S.

J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19.


Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.


Large-scale production of functional human lysozyme in transgenic cloned goats.

Yu H, Chen J, Liu S, Zhang A, Xu X, Wang X, Lu P, Cheng G.

J Biotechnol. 2013 Dec;168(4):676-83.


Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling.

Xiong K, Li S, Zhang H, Cui Y, Yu D, Li Y, Sun W, Fu Y, Teng Y, Liu Z, Zhou X, Xiao P, Li J, Liu H, Chen J.

Mol Biol Rep. 2013 Jul;40(7):4251-6. doi: 10.1007/s11033-013-2507-5. Epub 2013 May 5.


Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear transfer.

Bao L, Chen H, Jong U, Rim C, Li W, Lin X, Zhang D, Luo Q, Cui C, Huang H, Zhang Y, Xiao L, Fu Z.

Sci China Life Sci. 2014 Feb;57(2):263-8. doi: 10.1007/s11427-013-4601-2. Epub 2014 Jan 15.


Engineering disease resistant cattle.

Donovan DM, Kerr DE, Wall RJ.

Transgenic Res. 2005 Oct;14(5):563-7. Review.

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