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Results: 1 to 20 of 99

1.

Influence of oligospermines architecture on their suitability for siRNA delivery.

Elsayed M, Corrand V, Kolhatkar V, Xie Y, Kim NH, Kolhatkar R, Merkel OM.

Biomacromolecules. 2014 Apr 14;15(4):1299-310. doi: 10.1021/bm401849d. Epub 2014 Mar 4.

PMID:
24552396
[PubMed - in process]
2.

Asymmetrical N4,N9-diacyl spermines: SAR studies of nonviral lipopolyamine vectors for efficient siRNA delivery with silencing of EGFP reporter gene.

Blagbrough IS, Metwally AA, Ghonaim HM.

Mol Pharm. 2012 Jul 2;9(7):1853-61. doi: 10.1021/mp200428d. Epub 2012 Jun 6.

PMID:
22224453
[PubMed - indexed for MEDLINE]
3.

Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery.

Shim MS, Kwon YJ.

Bioconjug Chem. 2009 Mar 18;20(3):488-99. doi: 10.1021/bc800436v.

PMID:
19199781
[PubMed - indexed for MEDLINE]
4.

Efficient silencing of EGFP reporter gene with siRNA delivered by asymmetrical N4,N9-diacyl spermines.

Metwally AA, Reelfs O, Pourzand C, Blagbrough IS.

Mol Pharm. 2012 Jul 2;9(7):1862-76. doi: 10.1021/mp200429n. Epub 2012 Jun 6.

PMID:
22129427
[PubMed - indexed for MEDLINE]
5.

Biscarbamate cross-linked low molecular weight Polyethylenimine polycation as an efficient intra-cellular delivery cargo for cancer therapy.

Ge X, Feng J, Chen S, Zhang C, Ouyang Y, Liu Z, Yuan W.

J Nanobiotechnology. 2014 Apr 6;12:13. doi: 10.1186/1477-3155-12-13.

PMID:
24708586
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes.

Mao S, Neu M, Germershaus O, Merkel O, Sitterberg J, Bakowsky U, Kissel T.

Bioconjug Chem. 2006 Sep-Oct;17(5):1209-18.

PMID:
16984130
[PubMed - indexed for MEDLINE]
7.

Chitosan-graft-(PEI-β-cyclodextrin) copolymers and their supramolecular PEGylation for DNA and siRNA delivery.

Ping Y, Liu C, Zhang Z, Liu KL, Chen J, Li J.

Biomaterials. 2011 Nov;32(32):8328-41. doi: 10.1016/j.biomaterials.2011.07.038. Epub 2011 Aug 15.

PMID:
21840593
[PubMed - indexed for MEDLINE]
8.

Design and synthesis of N4,N9-disubstituted spermines for non-viral siRNA delivery--structure-activity relationship studies of siFection efficiency versus toxicity.

Soltan MK, Ghonaim HM, El Sadek M, Kull MA, El-aziz LA, Blagbrough IS.

Pharm Res. 2009 Feb;26(2):286-95. doi: 10.1007/s11095-008-9731-z. Epub 2008 Oct 9.

PMID:
18841447
[PubMed - indexed for MEDLINE]
9.

Bioreducible crosslinked polyelectrolyte complexes for MMP-2 siRNA delivery into human vascular smooth muscle cells.

Lee D, Kim D, Mok H, Jeong JH, Choi D, Kim SH.

Pharm Res. 2012 Aug;29(8):2213-24. doi: 10.1007/s11095-012-0750-4. Epub 2012 Apr 4.

PMID:
22477074
[PubMed - indexed for MEDLINE]
10.

N1,N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation.

Ghonaim HM, Li S, Blagbrough IS.

Pharm Res. 2010 Jan;27(1):17-29. doi: 10.1007/s11095-008-9764-3. Epub 2009 Oct 30.

PMID:
19876724
[PubMed - indexed for MEDLINE]
11.

Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)-b-polyethylenimine triblock copolymers: synthesis, characterization, and in vitro gene transfer properties.

Zhong Z, Feijen J, Lok MC, Hennink WE, Christensen LV, Yockman JW, Kim YH, Kim SW.

Biomacromolecules. 2005 Nov-Dec;6(6):3440-8.

PMID:
16283777
[PubMed - indexed for MEDLINE]
12.

Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan.

Varkouhi AK, Verheul RJ, Schiffelers RM, Lammers T, Storm G, Hennink WE.

Bioconjug Chem. 2010 Dec 15;21(12):2339-46. doi: 10.1021/bc1003789. Epub 2010 Nov 4.

PMID:
21049986
[PubMed - indexed for MEDLINE]
13.

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.

Merkel OM, Beyerle A, Librizzi D, Pfestroff A, Behr TM, Sproat B, Barth PJ, Kissel T.

Mol Pharm. 2009 Jul-Aug;6(4):1246-60. doi: 10.1021/mp900107v.

PMID:
19606864
[PubMed - indexed for MEDLINE]
14.

Gene silencing activity of siRNA polyplexes based on biodegradable polymers.

Varkouhi AK, Lammers T, Schiffelers RM, van Steenbergen MJ, Hennink WE, Storm G.

Eur J Pharm Biopharm. 2011 Apr;77(3):450-7. doi: 10.1016/j.ejpb.2010.11.016. Epub 2010 Nov 29.

PMID:
21118719
[PubMed - indexed for MEDLINE]
15.

Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery.

Ghonaim HM, Li S, Blagbrough IS.

Pharm Res. 2009 Jan;26(1):19-31. doi: 10.1007/s11095-008-9705-1. Epub 2008 Sep 10.

PMID:
18781381
[PubMed - indexed for MEDLINE]
16.

Controlled delivery of plasmid DNA and siRNA to intracellular targets using ketalized polyethylenimine.

Shim MS, Kwon YJ.

Biomacromolecules. 2008 Feb;9(2):444-55. doi: 10.1021/bm7007313. Epub 2008 Jan 11. Erratum in: Biomacromolecules. 2008 Apr;9(4):1355.

PMID:
18186606
[PubMed - indexed for MEDLINE]
17.

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers.

Ofek P, Fischer W, Calderón M, Haag R, Satchi-Fainaro R.

FASEB J. 2010 Sep;24(9):3122-34. doi: 10.1096/fj.09-149641. Epub 2010 Apr 12.

PMID:
20385622
[PubMed - indexed for MEDLINE]
Free Article
18.

Structure-activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides.

Fröhlich T, Edinger D, Kläger R, Troiber C, Salcher E, Badgujar N, Martin I, Schaffert D, Cengizeroglu A, Hadwiger P, Vornlocher HP, Wagner E.

J Control Release. 2012 Jun 28;160(3):532-41. doi: 10.1016/j.jconrel.2012.03.018. Epub 2012 Mar 24.

PMID:
22465674
[PubMed - indexed for MEDLINE]
19.

Factors influencing polycation/siRNA colloidal stability toward aerosol lung delivery.

Steele TW, Zhao X, Tarcha P, Kissel T.

Eur J Pharm Biopharm. 2012 Jan;80(1):14-24. doi: 10.1016/j.ejpb.2011.08.008. Epub 2011 Sep 6.

PMID:
21924355
[PubMed - indexed for MEDLINE]
20.

Vectors based on reducible polycations facilitate intracellular release of nucleic acids.

Read ML, Bremner KH, Oupický D, Green NK, Searle PF, Seymour LW.

J Gene Med. 2003 Mar;5(3):232-45.

PMID:
12666189
[PubMed - indexed for MEDLINE]
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