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Cytomegalovirus drives Vδ2neg γδ T cell inflation in many healthy virus carriers with increasing age.

Alejenef A, Pachnio A, Halawi M, Christmas SE, Moss PA, Khan N.

Clin Exp Immunol. 2014 Jun;176(3):418-28. doi: 10.1111/cei.12297.


Shared reactivity of V{delta}2(neg) {gamma}{delta} T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cells.

Halary F, Pitard V, Dlubek D, Krzysiek R, de la Salle H, Merville P, Dromer C, Emilie D, Moreau JF, Déchanet-Merville J.

J Exp Med. 2005 May 16;201(10):1567-78.


The role of Vδ2-negative γδ T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation.

Knight A, Madrigal AJ, Grace S, Sivakumaran J, Kottaridis P, Mackinnon S, Travers PJ, Lowdell MW.

Blood. 2010 Sep 23;116(12):2164-72. doi: 10.1182/blood-2010-01-255166. Epub 2010 Jun 24.


Long-term expansion of effector/memory Vdelta2-gammadelta T cells is a specific blood signature of CMV infection.

Pitard V, Roumanes D, Lafarge X, Couzi L, Garrigue I, Lafon ME, Merville P, Moreau JF, Déchanet-Merville J.

Blood. 2008 Aug 15;112(4):1317-24. doi: 10.1182/blood-2008-01-136713. Epub 2008 Jun 6.


Differential impact of age and cytomegalovirus infection on the γδ T cell compartment.

Roux A, Mourin G, Larsen M, Fastenackels S, Urrutia A, Gorochov G, Autran B, Donner C, Sidi D, Sibony-Prat J, Marchant A, Stern M, Sauce D, Appay V.

J Immunol. 2013 Aug 1;191(3):1300-6. doi: 10.4049/jimmunol.1202940. Epub 2013 Jul 1.


Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation.

Couzi L, Pitard V, Moreau JF, Merville P, Déchanet-Merville J.

Front Immunol. 2015 Jan 21;6:3. doi: 10.3389/fimmu.2015.00003. eCollection 2015. Review.


CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells.

Knight A, Arnouk H, Britt W, Gillespie GY, Cloud GA, Harkins L, Su Y, Lowdell MW, Lamb LS.

PLoS One. 2013 Aug 7;8(8):e68729. doi: 10.1371/journal.pone.0068729. eCollection 2013.


Implication of gammadelta T cells in the human immune response to cytomegalovirus.

Déchanet J, Merville P, Lim A, Retière C, Pitard V, Lafarge X, Michelson S, Méric C, Hallet MM, Kourilsky P, Potaux L, Bonneville M, Moreau JF.

J Clin Invest. 1999 May 15;103(10):1437-49.


Antitumor activity of gammadelta T cells reactive against cytomegalovirus-infected cells in a mouse xenograft tumor model.

Devaud C, Bilhere E, Loizon S, Pitard V, Behr C, Moreau JF, Dechanet-Merville J, Capone M.

Cancer Res. 2009 May 1;69(9):3971-8. doi: 10.1158/0008-5472.CAN-08-3037. Epub 2009 Apr 21.


Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses.

Lachmann R, Bajwa M, Vita S, Smith H, Cheek E, Akbar A, Kern F.

J Virol. 2012 Jan;86(2):1001-9. doi: 10.1128/JVI.00873-11. Epub 2011 Nov 9.


Neuroblastoma killing properties of Vδ2 and Vδ2-negative γδT cells following expansion by artificial antigen-presenting cells.

Fisher JP, Yan M, Heuijerjans J, Carter L, Abolhassani A, Frosch J, Wallace R, Flutter B, Capsomidis A, Hubank M, Klein N, Callard R, Gustafsson K, Anderson J.

Clin Cancer Res. 2014 Nov 15;20(22):5720-32. doi: 10.1158/1078-0432.CCR-13-3464. Epub 2014 Jun 3.


Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals.

Chidrawar S, Khan N, Wei W, McLarnon A, Smith N, Nayak L, Moss P.

Clin Exp Immunol. 2009 Mar;155(3):423-32. doi: 10.1111/j.1365-2249.2008.03785.x.


Human cytomegalovirus elicits fetal gammadelta T cell responses in utero.

Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, Twité N, Goldman M, Marchant A, Willems F.

J Exp Med. 2010 Apr 12;207(4):807-21. doi: 10.1084/jem.20090348. Epub 2010 Apr 5.


Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children.

Tu W, Chen S, Sharp M, Dekker C, Manganello AM, Tongson EC, Maecker HT, Holmes TH, Wang Z, Kemble G, Adler S, Arvin A, Lewis DB.

J Immunol. 2004 Mar 1;172(5):3260-7.


Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus.

Wistuba-Hamprecht K, Frasca D, Blomberg B, Pawelec G, Derhovanessian E.

Immun Ageing. 2013 Jul 3;10(1):26. doi: 10.1186/1742-4933-10-26.


Cytomegalovirus-induced gammadelta T cells associate with reduced cancer risk after kidney transplantation.

Couzi L, Levaillant Y, Jamai A, Pitard V, Lassalle R, Martin K, Garrigue I, Hawchar O, Siberchicot F, Moore N, Moreau JF, Dechanet-Merville J, Merville P.

J Am Soc Nephrol. 2010 Jan;21(1):181-8. doi: 10.1681/ASN.2008101072. Epub 2009 Aug 27.


Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults.

Turner JE, Campbell JP, Edwards KM, Howarth LJ, Pawelec G, Aldred S, Moss P, Drayson MT, Burns VE, Bosch JA.

Age (Dordr). 2014 Feb;36(1):287-97. doi: 10.1007/s11357-013-9557-4. Epub 2013 Jul 12.


Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.

Khan N, Hislop A, Gudgeon N, Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA.

J Immunol. 2004 Dec 15;173(12):7481-9.


Age-associated alteration of γδ T-cell repertoire and different profiles of activation-induced death of Vδ1 and Vδ2 T cells.

Michishita Y, Hirokawa M, Guo YM, Abe Y, Liu J, Ubukawa K, Fujishima N, Fujishima M, Yoshioka T, Kameoka Y, Saito H, Tagawa H, Takahashi N, Sawada K.

Int J Hematol. 2011 Sep;94(3):230-40. doi: 10.1007/s12185-011-0907-7. Epub 2011 Aug 20.


Healthy aging and latent infection with CMV lead to distinct changes in CD8+ and CD4+ T-cell subsets in the elderly.

Weinberger B, Lazuardi L, Weiskirchner I, Keller M, Neuner C, Fischer KH, Neuman B, Würzner R, Grubeck-Loebenstein B.

Hum Immunol. 2007 Feb;68(2):86-90. Epub 2006 Dec 5.

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