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Items: 1 to 20 of 103

1.

Inhibition of farnesyl pyrophosphate synthase prevents angiotensin II-induced cardiac fibrosis in vitro.

Li Z, Bi X, Wang M, Zhang J, Song J, Shen X, Han J, Fu G, Ye Y.

Clin Exp Immunol. 2014 Jun;176(3):429-37. doi: 10.1111/cei.12282.

2.

Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.

Yang J, Zhu HH, Chen GP, Ye Y, Zhao CZ, Mou Y, Hu SJ.

Int J Biochem Cell Biol. 2013 Mar;45(3):657-66. doi: 10.1016/j.biocel.2012.12.016. Epub 2012 Dec 29.

PMID:
23277274
3.

Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice.

Yang J, Mou Y, Wu T, Ye Y, Jiang JC, Zhao CZ, Zhu HH, Du CQ, Zhou L, Hu SJ.

Cardiovasc Res. 2013 Mar 1;97(3):490-9. doi: 10.1093/cvr/cvs347. Epub 2012 Nov 24.

4.

Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced fibrotic responses in vascular smooth muscle cells.

Du CQ, Liu XW, Zeng GZ, Jin HF, Tang LJ.

Int J Mol Med. 2015 Jun;35(6):1767-72. doi: 10.3892/ijmm.2015.2166. Epub 2015 Apr 2.

PMID:
25847782
5.

Knockdown of farnesylpyrophosphate synthase prevents angiotensin II-mediated cardiac hypertrophy.

Ye Y, Mou Y, Bai B, Li L, Chen GP, Hu SJ.

Int J Biochem Cell Biol. 2010 Dec;42(12):2056-64. doi: 10.1016/j.biocel.2010.09.010. Epub 2010 Sep 25.

PMID:
20884373
6.

Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7.

He X, Gao X, Peng L, Wang S, Zhu Y, Ma H, Lin J, Duan DD.

Circ Res. 2011 Jan 21;108(2):164-75. doi: 10.1161/CIRCRESAHA.110.234369. Epub 2010 Dec 2.

7.

Suppression of TGF-β1/Smad signaling pathway by sesamin contributes to the attenuation of myocardial fibrosis in spontaneously hypertensive rats.

Zhao M, Zheng S, Yang J, Wu Y, Ren Y, Kong X, Li W, Xuan J.

PLoS One. 2015 Mar 20;10(3):e0121312. doi: 10.1371/journal.pone.0121312. eCollection 2015.

8.

A-kinase anchoring protein-Lbc promotes pro-fibrotic signaling in cardiac fibroblasts.

Cavin S, Maric D, Diviani D.

Biochim Biophys Acta. 2014 Feb;1843(2):335-45. doi: 10.1016/j.bbamcr.2013.11.008. Epub 2013 Nov 22.

9.

NF-κB-mediated integrin-linked kinase regulation in angiotensin II-induced pro-fibrotic process in cardiac fibroblasts.

Thakur S, Li L, Gupta S.

Life Sci. 2014 Jun 27;107(1-2):68-75. doi: 10.1016/j.lfs.2014.04.030. Epub 2014 May 4.

PMID:
24802124
10.

Antifibrotic response of cardiac fibroblasts in hypertensive hearts through enhanced TIMP-1 expression by basic fibroblast growth factor.

Kinoshita T, Ishikawa Y, Arita M, Akishima-Fukasawa Y, Fujita K, Inomata N, Suzuki T, Namiki A, Mikami T, Ikeda T, Yamazaki J, Ishii T, Akasaka Y.

Cardiovasc Pathol. 2014 Mar-Apr;23(2):92-100. doi: 10.1016/j.carpath.2013.11.001. Epub 2013 Nov 14.

PMID:
24322055
11.

Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats.

Zhao W, Zhao T, Chen Y, Ahokas RA, Sun Y.

Mol Cell Biochem. 2008 Oct;317(1-2):43-50. doi: 10.1007/s11010-008-9803-8. Epub 2008 Jun 26.

PMID:
18581202
12.

Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF β/Smad activation and cardiac fibrosis induced by angiotensin II.

Ma F, Li Y, Jia L, Han Y, Cheng J, Li H, Qi Y, Du J.

PLoS One. 2012;7(5):e35144. doi: 10.1371/journal.pone.0035144. Epub 2012 May 4.

13.

Curcumin attenuates cardiac fibrosis in spontaneously hypertensive rats through PPAR-γ activation.

Meng Z, Yu XH, Chen J, Li L, Li S.

Acta Pharmacol Sin. 2014 Oct;35(10):1247-56. doi: 10.1038/aps.2014.63. Epub 2014 Aug 18.

14.

PPAR-γ activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1.

Hou X, Zhang Y, Shen YH, Liu T, Song S, Cui L, Bu P.

Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. doi: 10.1016/j.ejphar.2013.05.021. Epub 2013 Jun 18.

PMID:
23791613
15.

Chronic inhibition of farnesyl pyrophosphate synthase attenuates cardiac hypertrophy and fibrosis in spontaneously hypertensive rats.

Li L, Chen GP, Yang Y, Ye Y, Yao L, Hu SJ.

Biochem Pharmacol. 2010 Feb 1;79(3):399-406. doi: 10.1016/j.bcp.2009.08.033. Epub 2009 Oct 2.

PMID:
19800872
16.

Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.

Chen K, Mehta JL, Li D, Joseph L, Joseph J.

Circ Res. 2004 Dec 10;95(12):1167-73. Epub 2004 Nov 11.

17.

Resveratrol inhibits high glucose induced collagen upregulation in cardiac fibroblasts through regulating TGF-β1-Smad3 signaling pathway.

Liu J, Zhuo X, Liu W, Wan Z, Liang X, Gao S, Yuan Z, Wu Y.

Chem Biol Interact. 2015 Feb 5;227:45-52. doi: 10.1016/j.cbi.2014.12.031. Epub 2015 Jan 2.

PMID:
25559857
18.

Sp1 Mediates a Therapeutic Role of MiR-7a/b in Angiotensin II-Induced Cardiac Fibrosis via Mechanism Involving the TGF-β and MAPKs Pathways in Cardiac Fibroblasts.

Li R, Xiao J, Qing X, Xing J, Xia Y, Qi J, Liu X, Zhang S, Sheng X, Zhang X, Ji X.

PLoS One. 2015 Apr 29;10(4):e0125513. doi: 10.1371/journal.pone.0125513. eCollection 2015.

19.
20.

Induction of cardiac fibrosis by angiotensin II.

Lijnen PJ, Petrov VV, Fagard RH.

Methods Find Exp Clin Pharmacol. 2000 Dec;22(10):709-23.

PMID:
11346891
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