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Results: 1 to 20 of 104

1.

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.

Chopra P, Papale LA, White AT, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS.

BMC Genomics. 2014 Feb 13;15:131. doi: 10.1186/1471-2164-15-131.

PMID:
24524199
[PubMed - in process]
Free PMC Article
2.

High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.

Davis T, Vaisvila R.

J Vis Exp. 2011 Feb 1;(48). pii: 2661. doi: 10.3791/2661.

PMID:
21307836
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G, Chandran S, Hay DC, Bradley M, Wilmut I, De Sousa P.

Cell Res. 2011 Sep;21(9):1332-42. doi: 10.1038/cr.2011.113. Epub 2011 Jul 12.

PMID:
21747414
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

5-hydroxymethylcytosine: a new insight into epigenetics in cancer.

Ye C, Li L.

Cancer Biol Ther. 2014 Jan;15(1):10-5. doi: 10.4161/cbt.27144. Epub 2013 Nov 19. Review.

PMID:
24253310
[PubMed - indexed for MEDLINE]
5.

Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.

Song CX, He C.

Acc Chem Res. 2011 Sep 20;44(9):709-17. doi: 10.1021/ar2000502. Epub 2011 May 3.

PMID:
21539303
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease.

Wang F, Yang Y, Lin X, Wang JQ, Wu YS, Xie W, Wang D, Zhu S, Liao YQ, Sun Q, Yang YG, Luo HR, Guo C, Han C, Tang TS.

Hum Mol Genet. 2013 Sep 15;22(18):3641-53. doi: 10.1093/hmg/ddt214. Epub 2013 May 12.

PMID:
23669348
[PubMed - indexed for MEDLINE]
Free Article
7.

Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus.

Al-Mahdawi S, Sandi C, Mouro Pinto R, Pook MA.

PLoS One. 2013 Sep 4;8(9):e74956. doi: 10.1371/journal.pone.0074956. eCollection 2013.

PMID:
24023969
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Biochemical characterization of recombinant β-glucosyltransferase and analysis of global 5-hydroxymethylcytosine in unique genomes.

Terragni J, Bitinaite J, Zheng Y, Pradhan S.

Biochemistry. 2012 Feb 7;51(5):1009-19. doi: 10.1021/bi2014739. Epub 2012 Jan 27. Erratum in: Biochemistry. 2012 Aug 7;51(31):6261.

PMID:
22229759
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.

Wen L, Li X, Yan L, Tan Y, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C, Li R, Tang F, Qiao J.

Genome Biol. 2014 Mar 4;15(3):R49. doi: 10.1186/gb-2014-15-3-r49.

PMID:
24594098
[PubMed - in process]
Free PMC Article
10.

Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line.

Zhang LT, Zhang LJ, Zhang JJ, Ye XX, Xie AM, Chen LY, Kang JX, Cai C.

Bioanalysis. 2013 Apr;5(7):839-45. doi: 10.4155/bio.13.28.

PMID:
23534428
[PubMed - indexed for MEDLINE]
11.

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG.

Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033.

PMID:
22980977
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.

Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, Jin P.

Nat Neurosci. 2011 Oct 30;14(12):1607-16. doi: 10.1038/nn.2959.

PMID:
22037496
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.

Chen ML, Shen F, Huang W, Qi JH, Wang Y, Feng YQ, Liu SM, Yuan BF.

Clin Chem. 2013 May;59(5):824-32. doi: 10.1373/clinchem.2012.193938. Epub 2013 Jan 23.

PMID:
23344498
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Selective capture of 5-hydroxymethylcytosine from genomic DNA.

Li Y, Song CX, He C, Jin P.

J Vis Exp. 2012 Oct 5;(68). pii: 4441. doi: 10.3791/4441.

PMID:
23070273
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hydroxymethylation as a Novel Environmental Biosensor.

Dao T, Cheng RY, Revelo MP, Mitzner W, Tang W.

Curr Environ Health Rep. 2014 Mar 1;1(1):1-10.

PMID:
24860723
[PubMed]
16.

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A.

Nucleic Acids Res. 2013 Sep;41(16):e157. doi: 10.1093/nar/gkt601. Epub 2013 Jul 16.

PMID:
23861445
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S.

Oncotarget. 2011 Aug;2(8):627-37.

PMID:
21896958
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation.

Gao F, Xia Y, Wang J, Luo H, Gao Z, Han X, Zhang J, Huang X, Yao Y, Lu H, Yi N, Zhou B, Lin Z, Wen B, Zhang X, Yang H, Wang J.

Epigenetics. 2013 Apr;8(4):421-30. doi: 10.4161/epi.24280. Epub 2013 Mar 15.

PMID:
23502161
[PubMed - in process]
Free PMC Article
19.

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A.

PLoS One. 2010 Jan 26;5(1):e8888. doi: 10.1371/journal.pone.0008888.

PMID:
20126651
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

5-Hydroxymethylcytosine, the sixth base of the genome.

Münzel M, Globisch D, Carell T.

Angew Chem Int Ed Engl. 2011 Jul 11;50(29):6460-8. doi: 10.1002/anie.201101547. Epub 2011 Jun 17. Review.

PMID:
21688365
[PubMed - indexed for MEDLINE]

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