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Results: 1 to 20 of 96

1.

New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners.

Zhang W, Liu Y, Yan J, Cao S, Bai F, Yang Y, Huang S, Yao L, Anzai Y, Kato F, Podust LM, Sherman DH, Li S.

J Am Chem Soc. 2014 Mar 5;136(9):3640-6. doi: 10.1021/ja4130302. Epub 2014 Feb 25.

PMID:
24521145
[PubMed - in process]
2.

Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.

Li S, Tietz DR, Rutaganira FU, Kells PM, Anzai Y, Kato F, Pochapsky TC, Sherman DH, Podust LM.

J Biol Chem. 2012 Nov 2;287(45):37880-90. doi: 10.1074/jbc.M112.410340. Epub 2012 Sep 5.

PMID:
22952225
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin.

Anzai Y, Tsukada S, Sakai A, Masuda R, Harada C, Domeki A, Li S, Kinoshita K, Sherman DH, Kato F.

Antimicrob Agents Chemother. 2012 Jul;56(7):3648-56. doi: 10.1128/AAC.06063-11. Epub 2012 Apr 30.

PMID:
22547618
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.

Anzai Y, Li S, Chaulagain MR, Kinoshita K, Kato F, Montgomery J, Sherman DH.

Chem Biol. 2008 Sep 22;15(9):950-9. doi: 10.1016/j.chembiol.2008.07.014.

PMID:
18804032
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

P450BM-3; a tale of two domains--or is it three?

Peterson JA, Sevrioukova I, Truan G, Graham-Lorence SE.

Steroids. 1997 Jan;62(1):117-23. Review.

PMID:
9029725
[PubMed - indexed for MEDLINE]
6.

Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase.

Li S, Chaulagain MR, Knauff AR, Podust LM, Montgomery J, Sherman DH.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18463-8. doi: 10.1073/pnas.0907203106. Epub 2009 Oct 15.

PMID:
19833867
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A gene-fusion approach to enabling plant cytochromes p450 for biocatalysis.

Schückel J, Rylott EL, Grogan G, Bruce NC.

Chembiochem. 2012 Dec 21;13(18):2758-63. doi: 10.1002/cbic.201200572. Epub 2012 Nov 5.

PMID:
23129550
[PubMed - indexed for MEDLINE]
8.

Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.

Yamazaki H, Gillam EM, Dong MS, Johnson WW, Guengerich FP, Shimada T.

Arch Biochem Biophys. 1997 Jun 15;342(2):329-37.

PMID:
9186495
[PubMed - indexed for MEDLINE]
9.

Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2).

Chun YJ, Shimada T, Sanchez-Ponce R, Martin MV, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC, Guengerich FP.

J Biol Chem. 2007 Jun 15;282(24):17486-500. Epub 2007 Apr 19.

PMID:
17446171
[PubMed - indexed for MEDLINE]
Free Article
10.

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

Ueng YF, Kuwabara T, Chun YJ, Guengerich FP.

Biochemistry. 1997 Jan 14;36(2):370-81.

PMID:
9003190
[PubMed - indexed for MEDLINE]
11.

Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.

Hayashi K, Sakaki T, Kominami S, Inouye K, Yabusaki Y.

Arch Biochem Biophys. 2000 Sep 1;381(1):164-70.

PMID:
11019832
[PubMed - indexed for MEDLINE]
12.

Steroid hydroxylations: a paradigm for cytochrome P450 catalyzed mammalian monooxygenation reactions.

Estabrook RW.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):290-8. Epub 2005 Aug 30.

PMID:
16143297
[PubMed - indexed for MEDLINE]
13.

Regio- and stereospecific hydroxylation of various steroids at the 16α position of the D ring by the streptomyces griseus cytochrome P450 CYP154C3.

Makino T, Katsuyama Y, Otomatsu T, Misawa N, Ohnishi Y.

Appl Environ Microbiol. 2014 Feb;80(4):1371-9. doi: 10.1128/AEM.03504-13. Epub 2013 Dec 13.

PMID:
24334658
[PubMed - in process]
Free PMC Article
14.

Structural basis for effector control and redox partner recognition in cytochrome P450.

Tripathi S, Li H, Poulos TL.

Science. 2013 Jun 7;340(6137):1227-30. doi: 10.1126/science.1235797.

PMID:
23744947
[PubMed - indexed for MEDLINE]
Free Article
15.
16.

A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center.

Roberts GA, Celik A, Hunter DJ, Ost TW, White JH, Chapman SK, Turner NJ, Flitsch SL.

J Biol Chem. 2003 Dec 5;278(49):48914-20. Epub 2003 Sep 27.

PMID:
14514666
[PubMed - indexed for MEDLINE]
Free Article
17.

Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase.

Liu Y, Wang C, Yan J, Zhang W, Guan W, Lu X, Li S.

Biotechnol Biofuels. 2014 Feb 24;7(1):28. doi: 10.1186/1754-6834-7-28.

PMID:
24565055
[PubMed]
Free PMC Article
18.

Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.

Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.

Drug Metab Dispos. 1993 Jul-Aug;21(4):645-56. Erratum in: Drug Metab Dispos Biol Fate Chem 1993 Nov-Dec;21(6):1174.

PMID:
8104124
[PubMed - indexed for MEDLINE]
19.
20.

Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes.

Shimada T, Mernaugh RL, Guengerich FP.

Arch Biochem Biophys. 2005 Mar 1;435(1):207-16.

PMID:
15680923
[PubMed - indexed for MEDLINE]

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