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Items: 1 to 20 of 164


Negative regulation by PD-L1 during drug-specific priming of IL-22-secreting T cells and the influence of PD-1 on effector T cell function.

Gibson A, Ogese M, Sullivan A, Wang E, Saide K, Whitaker P, Peckham D, Faulkner L, Park BK, Naisbitt DJ.

J Immunol. 2014 Mar 15;192(6):2611-21. doi: 10.4049/jimmunol.1302720. Epub 2014 Feb 7.


PD-1/PD-L1 expression on CD(4+) T cells and myeloid DCs correlates with the immune pathogenesis of atrial fibrillation.

Liu L, Zheng Q, Lee J, Ma Z, Zhu Q, Wang Z.

J Cell Mol Med. 2015 Jun;19(6):1223-33. doi: 10.1111/jcmm.12467. Epub 2015 Mar 26.


Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG, Kaufmann DE.

J Virol. 2014 Mar;88(5):2508-18. doi: 10.1128/JVI.02034-13. Epub 2013 Dec 18.


Cytosine-phosphate-guanosine-DNA induces CD274 expression in human B cells and suppresses T helper type 2 cytokine production in pollen antigen-stimulated CD4-positive cells.

Kubo S, Yamada T, Osawa Y, Ito Y, Narita N, Fujieda S.

Clin Exp Immunol. 2012 Jul;169(1):1-9. doi: 10.1111/j.1365-2249.2012.04585.x.


Different roles of PD-L1 and FasL in immunomodulation mediated by human placenta-derived mesenchymal stem cells.

Gu YZ, Xue Q, Chen YJ, Yu GH, Qing MD, Shen Y, Wang MY, Shi Q, Zhang XG.

Hum Immunol. 2013 Mar;74(3):267-76. doi: 10.1016/j.humimm.2012.12.011. Epub 2012 Dec 20.


Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.

Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M.

PLoS One. 2012;7(10):e46776. doi: 10.1371/journal.pone.0046776. Epub 2012 Oct 9.


IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype.

Casey KA, Mescher MF.

J Immunol. 2007 Jun 15;178(12):7640-8.


Mycobacterium tuberculosis PstS1 amplifies IFN-γ and induces IL-17/IL-22 responses by unrelated memory CD4+ T cells via dendritic cell activation.

Palma C, Schiavoni G, Abalsamo L, Mattei F, Piccaro G, Sanchez M, Fernandez C, Singh M, Gabriele L.

Eur J Immunol. 2013 Sep;43(9):2386-97. doi: 10.1002/eji.201243245. Epub 2013 Jul 15.


The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

Brusa D, Serra S, Coscia M, Rossi D, D'Arena G, Laurenti L, Jaksic O, Fedele G, Inghirami G, Gaidano G, Malavasi F, Deaglio S.

Haematologica. 2013 Jun;98(6):953-63. doi: 10.3324/haematol.2012.077537. Epub 2013 Jan 8.


IL-2 induces Fas ligand/Fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones.

Esser MT, Dinglasan RD, Krishnamurthy B, Gullo CA, Graham MB, Braciale VL.

J Immunol. 1997 Jun 15;158(12):5612-8.


Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis.

Pittet CL, Newcombe J, Prat A, Arbour N.

J Neuroinflammation. 2011 Nov 8;8:155. doi: 10.1186/1742-2094-8-155.


Analysis of Th1 and Th2 cytokines expressing CD4+ and CD8+ T cells in rheumatoid arthritis by flow cytometry.

Berner B, Akça D, Jung T, Muller GA, Reuss-Borst MA.

J Rheumatol. 2000 May;27(5):1128-35.


Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model.

Yu P, Steel JC, Zhang M, Morris JC, Waitz R, Fasso M, Allison JP, Waldmann TA.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6187-92. doi: 10.1073/pnas.1203479109. Epub 2012 Apr 2.


Blockade of programmed death receptor-1 signaling restores expression of mostly proinflammatory cytokines in anergic cytomegalovirus-specific T cells.

Dirks J, Egli A, Sester U, Sester M, Hirsch HH.

Transpl Infect Dis. 2013 Feb;15(1):79-89. doi: 10.1111/tid.12025. Epub 2012 Nov 26.


Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.

Duraiswamy J, Kaluza KM, Freeman GJ, Coukos G.

Cancer Res. 2013 Jun 15;73(12):3591-603. doi: 10.1158/0008-5472.CAN-12-4100. Epub 2013 Apr 30.


Suppression of IL-22-producing T helper 22 cells by RPE cells via PD-L1/PD-1 interactions.

Sugita S, Kawazoe Y, Imai A, Usui Y, Takahashi M, Mochizuki M.

Invest Ophthalmol Vis Sci. 2013 Oct 23;54(10):6926-33. doi: 10.1167/iovs.13-12703.


The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands.

Kinter AL, Godbout EJ, McNally JP, Sereti I, Roby GA, O'Shea MA, Fauci AS.

J Immunol. 2008 Nov 15;181(10):6738-46.


Tumor PD-L1 co-stimulates primary human CD8(+) cytotoxic T cells modified to express a PD1:CD28 chimeric receptor.

Prosser ME, Brown CE, Shami AF, Forman SJ, Jensen MC.

Mol Immunol. 2012 Jul;51(3-4):263-72. doi: 10.1016/j.molimm.2012.03.023. Epub 2012 Apr 11.

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