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Items: 1 to 20 of 121

1.

Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses.

Herath S, Benlahrech A, Papagatsias T, Athanasopoulos T, Bouzeboudjen Z, Hervouet C, Klavinskis L, Meiser A, Kelleher P, Dickson G, Patterson S.

PLoS One. 2014 Feb 5;9(2):e88327. doi: 10.1371/journal.pone.0088327. eCollection 2014.

2.

Vaccination with a fusion protein that introduces HIV-1 gag antigen into a multitrimer CD40L construct results in enhanced CD8+ T cell responses and protection from viral challenge by vaccinia-gag.

Gupta S, Termini JM, Raffa FN, Williams CA, Kornbluth RS, Stone GW.

J Virol. 2014 Feb;88(3):1492-501. doi: 10.1128/JVI.02229-13. Epub 2013 Nov 13.

3.

Fragmentation of SIV-gag vaccine induces broader T cell responses.

Benlahrech A, Meiser A, Herath S, Papagatsias T, Athanasopoulos T, Li F, Self S, Bachy V, Hervouet C, Logan K, Klavinskis L, Dickson G, Patterson S.

PLoS One. 2012;7(10):e48038. doi: 10.1371/journal.pone.0048038. Epub 2012 Oct 31.

4.

PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific T cell immunity elicited by dendritic cell-directed lentiviral vaccines.

Dai B, Xiao L, Bryson PD, Fang J, Wang P.

Mol Ther. 2012 Sep;20(9):1800-9. doi: 10.1038/mt.2012.98. Epub 2012 May 15.

5.

Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine.

Kanagavelu SK, Snarsky V, Termini JM, Gupta S, Barzee S, Wright JA, Khan WN, Kornbluth RS, Stone GW.

Vaccine. 2012 Jan 17;30(4):691-702. doi: 10.1016/j.vaccine.2011.11.088. Epub 2011 Dec 4.

6.

mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients.

Van Gulck E, Vlieghe E, Vekemans M, Van Tendeloo VF, Van De Velde A, Smits E, Anguille S, Cools N, Goossens H, Mertens L, De Haes W, Wong J, Florence E, Vanham G, Berneman ZN.

AIDS. 2012 Feb 20;26(4):F1-12. doi: 10.1097/QAD.0b013e32834f33e8.

PMID:
22156965
7.

Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes.

Niu L, Termini JM, Kanagavelu SK, Gupta S, Rolland MM, Kulkarni V, Pavlakis GN, Felber BK, Mullins JI, Fischl MA, Stone GW.

Vaccine. 2011 Mar 3;29(11):2110-9. doi: 10.1016/j.vaccine.2010.12.131. Epub 2011 Jan 15.

8.

Dendritic cells infected by recombinant rabies virus vaccine vector expressing HIV-1 Gag are immunogenic even in the presence of vector-specific immunity.

Wanjalla CN, Faul EJ, Gomme EA, Schnell MJ.

Vaccine. 2010 Dec 10;29(1):130-40. doi: 10.1016/j.vaccine.2010.08.042. Epub 2010 Aug 20.

9.

Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice.

Maamary J, Array F, Gao Q, García-Sastre A, Steinman RM, Palese P, Nchinda G.

J Virol. 2011 Mar;85(5):2235-46. doi: 10.1128/JVI.02036-10. Epub 2010 Dec 15.

10.

Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals.

Climent N, Guerra S, García F, Rovira C, Miralles L, Gómez CE, Piqué N, Gil C, Gatell JM, Esteban M, Gallart T.

PLoS One. 2011;6(5):e19644. doi: 10.1371/journal.pone.0019644. Epub 2011 May 18.

11.

Interleukin-12p70 expression by dendritic cells of HIV-1-infected patients fails to stimulate gag-specific immune responses.

Van Gulck E, Cools N, Atkinson D, Bracke L, Vereecken K, Vekemans M, Van Tendeloo VF, Berneman ZN, Vanham G.

Clin Dev Immunol. 2012;2012:184979. doi: 10.1155/2012/184979. Epub 2012 Jul 12.

12.

Recombinant adeno-associated virus vectors induce functionally impaired transgene product-specific CD8+ T cells in mice.

Lin SW, Hensley SE, Tatsis N, Lasaro MO, Ertl HC.

J Clin Invest. 2007 Dec;117(12):3958-70.

13.

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

Gómez CE, Perdiguero B, Jiménez V, Filali-Mouhim A, Ghneim K, Haddad EK, Quakkelaar ED, Delaloye J, Harari A, Roger T, Duhen T, Sékaly RP, Melief CJ, Calandra T, Sallusto F, Lanzavecchia A, Wagner R, Pantaleo G, Esteban M.

PLoS One. 2012;7(4):e35485. doi: 10.1371/journal.pone.0035485. Epub 2012 Apr 19. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/44b8f849-7885-4ad0-8fc9-b252c9ee1790. Dunhen, Thomas [corrected to Duhen, Thomas]. PLoS One. 2012;7(5): doi/10.1371/annotation/09c18b10-8433-4d64-be1c-61e578cc088b. Quakkerlaar [corrected to Quakkelaar, Esther D]..

14.

PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice.

Zhou J, Cheung AK, Tan Z, Wang H, Yu W, Du Y, Kang Y, Lu X, Liu L, Yuen KY, Chen Z.

J Clin Invest. 2013 Jun;123(6):2629-42. doi: 10.1172/JCI64704. Epub 2013 May 1.

16.

Loading dendritic cells with PLA-p24 nanoparticles or MVA expressing HIV genes induces HIV-1-specific T cell responses.

Climent N, Munier S, Piqué N, García F, Pavot V, Primard C, Casanova V, Gatell JM, Verrier B, Gallart T.

Vaccine. 2014 Oct 29;32(47):6266-76. doi: 10.1016/j.vaccine.2014.09.010. Epub 2014 Sep 19.

PMID:
25240755
17.
18.

Robust immunity to an auxotrophic Mycobacterium bovis BCG-VLP prime-boost HIV vaccine candidate in a nonhuman primate model.

Chege GK, Burgers WA, Stutz H, Meyers AE, Chapman R, Kiravu A, Bunjun R, Shephard EG, Jacobs WR Jr, Rybicki EP, Williamson AL.

J Virol. 2013 May;87(9):5151-60. doi: 10.1128/JVI.03178-12. Epub 2013 Feb 28.

19.

Efficient in vitro expansion of human immunodeficiency virus (HIV)-specific T-cell responses by gag mRNA-electroporated dendritic cells from treated and untreated HIV type 1-infected individuals.

Van Gulck ER, Vanham G, Heyndrickx L, Coppens S, Vereecken K, Atkinson D, Florence E, Kint I, Berneman ZN, Van Tendeloo V.

J Virol. 2008 Apr;82(7):3561-73. doi: 10.1128/JVI.02080-07. Epub 2008 Jan 30.

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