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Results: 1 to 20 of 101

Related Citations for PubMed (Select 24502544)

1.

Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase.

Wang S, Thomas K, Schramm VL.

Biochemistry. 2014 Mar 11;53(9):1527-35. doi: 10.1021/bi401589n. Epub 2014 Feb 21.

2.

Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.

Guan R, Ho MC, Brenowitz M, Tyler PC, Evans GB, Almo SC, Schramm VL.

Biochemistry. 2011 Nov 29;50(47):10408-17. doi: 10.1021/bi201321x. Epub 2011 Nov 7.

3.

Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.

Guan R, Tyler PC, Evans GB, Schramm VL.

Biochemistry. 2013 Nov 19;52(46):8313-22. doi: 10.1021/bi401188w. Epub 2013 Nov 8.

4.

Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.

Singh V, Evans GB, Lenz DH, Mason JM, Clinch K, Mee S, Painter GF, Tyler PC, Furneaux RH, Lee JE, Howell PL, Schramm VL.

J Biol Chem. 2005 May 6;280(18):18265-73. Epub 2005 Mar 4.

5.

Mechanism of substrate specificity in 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases.

Siu KK, Asmus K, Zhang AN, Horvatin C, Li S, Liu T, Moffatt B, Woods VL Jr, Howell PL.

J Struct Biol. 2011 Jan;173(1):86-98. doi: 10.1016/j.jsb.2010.06.006. Epub 2010 Jun 8.

6.

Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.

Singh V, Shi W, Almo SC, Evans GB, Furneaux RH, Tyler PC, Painter GF, Lenz DH, Mee S, Zheng R, Schramm VL.

Biochemistry. 2006 Oct 31;45(43):12929-41.

7.

Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases.

Siu KK, Lee JE, Sufrin JR, Moffatt BA, McMillan M, Cornell KA, Isom C, Howell PL.

J Mol Biol. 2008 Apr 18;378(1):112-28. doi: 10.1016/j.jmb.2008.01.088. Epub 2008 Feb 8.

8.

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.

Lee JE, Singh V, Evans GB, Tyler PC, Furneaux RH, Cornell KA, Riscoe MK, Schramm VL, Howell PL.

J Biol Chem. 2005 May 6;280(18):18274-82. Epub 2005 Mar 3.

9.

Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.

Siu KK, Lee JE, Smith GD, Horvatin-Mrakovcic C, Howell PL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):343-50. doi: 10.1107/S1744309108009275. Epub 2008 Apr 30.

10.

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.

Singh V, Shi W, Evans GB, Tyler PC, Furneaux RH, Almo SC, Schramm VL.

Biochemistry. 2004 Jan 13;43(1):9-18.

PMID:
14705926
11.

Femtomolar inhibitors bind to 5'-methylthioadenosine nucleosidases with favorable enthalpy and entropy.

Thomas K, Haapalainen AM, Burgos ES, Evans GB, Tyler PC, Gulab S, Guan R, Schramm VL.

Biochemistry. 2012 Sep 25;51(38):7541-50. doi: 10.1021/bi3009938. Epub 2012 Sep 11.

PMID:
22931458
12.

Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis.

Lee JE, Smith GD, Horvatin C, Huang DJ, Cornell KA, Riscoe MK, Howell PL.

J Mol Biol. 2005 Sep 23;352(3):559-74.

PMID:
16109423
13.

Transition state analogues in quorum sensing and SAM recycling.

Schramm VL, Gutierrez JA, Cordovano G, Basu I, Guha C, Belbin TJ, Evans GB, Tyler PC, Furneaux RH.

Nucleic Acids Symp Ser (Oxf). 2008;(52):75-6. doi: 10.1093/nass/nrn038.

14.
15.

Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.

Rinaldo-Matthis A, Wing C, Ghanem M, Deng H, Wu P, Gupta A, Tyler PC, Evans GB, Furneaux RH, Almo SC, Wang CC, Schramm VL.

Biochemistry. 2007 Jan 23;46(3):659-68.

16.

Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway.

Kim RQ, Offen WA, Davies GJ, Stubbs KA.

Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):177-85. doi: 10.1107/S1399004713026655. Epub 2013 Dec 31.

PMID:
24419390
17.

Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.

Taylor EA, Rinaldo-Matthis A, Li L, Ghanem M, Hazleton KZ, Cassera MB, Almo SC, Schramm VL.

Biochemistry. 2007 Oct 30;46(43):12405-15. Epub 2007 Oct 6.

PMID:
17918964
18.
19.

Active Site and Remote Contributions to Catalysis in Methylthioadenosine Nucleosidases.

Schramm VL, Thomas K, Cameron SA, Almo SC, Burgos ES, Gulab SA.

Biochemistry. 2015 Mar 25. [Epub ahead of print]

PMID:
25806409
20.

Altered thermodynamics from remote mutations altering human toward bovine purine nucleoside phosphorylase.

Ghanem M, Li L, Wing C, Schramm VL.

Biochemistry. 2008 Feb 26;47(8):2559-64. doi: 10.1021/bi702132e.

PMID:
18281956
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