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Items: 1 to 20 of 147

1.

De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function.

Han A, Stoilov P, Linares AJ, Zhou Y, Fu XD, Black DL.

PLoS Comput Biol. 2014 Jan 30;10(1):e1003442. doi: 10.1371/journal.pcbi.1003442. eCollection 2014 Jan.

2.

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.

Bielli P, Bordi M, Di Biasio V, Sette C.

Nucleic Acids Res. 2014 Oct 29;42(19):12070-81. doi: 10.1093/nar/gku922. Epub 2014 Oct 7.

3.

Structure of PTB bound to RNA: specific binding and implications for splicing regulation.

Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black DL, Allain FH.

Science. 2005 Sep 23;309(5743):2054-7.

4.

PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis.

Izaguirre DI, Zhu W, Hai T, Cheung HC, Krahe R, Cote GJ.

Mol Carcinog. 2012 Nov;51(11):895-906. doi: 10.1002/mc.20859. Epub 2011 Oct 4.

5.

Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines.

Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ.

Brain. 2009 Aug;132(Pt 8):2277-88. doi: 10.1093/brain/awp153. Epub 2009 Jun 8.

6.

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts.

Li YI, Sanchez-Pulido L, Haerty W, Ponting CP.

Genome Res. 2015 Jan;25(1):1-13. doi: 10.1101/gr.181990.114.

7.

An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing.

Zuccato E, Buratti E, Stuani C, Baralle FE, Pagani F.

J Biol Chem. 2004 Apr 23;279(17):16980-8. Epub 2004 Feb 13.

8.

Exon repression by polypyrimidine tract binding protein.

Amir-Ahmady B, Boutz PL, Markovtsov V, Phillips ML, Black DL.

RNA. 2005 May;11(5):699-716.

9.

ABLIM1 splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1.

Ohsawa N, Koebis M, Mitsuhashi H, Nishino I, Ishiura S.

Genes Cells. 2015 Feb;20(2):121-34. doi: 10.1111/gtc.12201. Epub 2014 Nov 18.

10.

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5' splice site choice.

Hamid FM, Makeyev EV.

PLoS Genet. 2014 Nov 6;10(11):e1004771. doi: 10.1371/journal.pgen.1004771. eCollection 2014 Nov.

11.

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB.

Genes Dev. 2012 Jul 15;26(14):1626-42. doi: 10.1101/gad.191338.112.

12.
13.

A splicing repressor domain in polypyrimidine tract-binding protein.

Robinson F, Smith CW.

J Biol Chem. 2006 Jan 13;281(2):800-6. Epub 2005 Nov 9.

14.

Significance of Polypyrimidine Tract-Binding Protein 1 Expression in Colorectal Cancer.

Takahashi H, Nishimura J, Kagawa Y, Kano Y, Takahashi Y, Wu X, Hiraki M, Hamabe A, Konno M, Haraguchi N, Takemasa I, Mizushima T, Ishii M, Mimori K, Ishii H, Doki Y, Mori M, Yamamoto H.

Mol Cancer Ther. 2015 Jul;14(7):1705-16. doi: 10.1158/1535-7163.MCT-14-0142. Epub 2015 Apr 22.

15.

The domains of polypyrimidine tract binding protein have distinct RNA structural preferences.

Clerte C, Hall KB.

Biochemistry. 2009 Mar 17;48(10):2063-74. doi: 10.1021/bi8016872.

16.

U1 snRNA directly interacts with polypyrimidine tract-binding protein during splicing repression.

Sharma S, Maris C, Allain FH, Black DL.

Mol Cell. 2011 Mar 4;41(5):579-88. doi: 10.1016/j.molcel.2011.02.012.

17.

Regulation and functional significance of CDC42 alternative splicing in ovarian cancer.

He X, Yuan C, Yang J.

Oncotarget. 2015 Oct 6;6(30):29651-63. doi: 10.18632/oncotarget.4865.

18.

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.

Ferrarese R, Harsh GR 4th, Yadav AK, Bug E, Maticzka D, Reichardt W, Dombrowski SM, Miller TE, Masilamani AP, Dai F, Kim H, Hadler M, Scholtens DM, Yu IL, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte CW, He X, Prinz M, Chandler JP, Vogel H, Chakravarti A, Rich JN, Carro MS, Bredel M.

J Clin Invest. 2014 Jul;124(7):2861-76. doi: 10.1172/JCI68836. Epub 2014 May 27.

19.

Polypyrimidine tract-binding protein 1 regulates the alternative splicing of dopamine receptor D2.

Sasabe T, Futai E, Ishiura S.

J Neurochem. 2011 Jan;116(1):76-81. doi: 10.1111/j.1471-4159.2010.07086.x. Epub 2010 Dec 2.

20.

Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2.

Keppetipola NM, Yeom KH, Hernandez AL, Bui T, Sharma S, Black DL.

RNA. 2016 Aug;22(8):1172-80. doi: 10.1261/rna.057505.116. Epub 2016 Jun 10.

PMID:
27288314
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