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Items: 1 to 20 of 140

1.

Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo.

Bansal R, Prakash J, De Ruiter M, Poelstra K.

J Control Release. 2014 Apr 10;179:18-24. doi: 10.1016/j.jconrel.2014.01.022. Epub 2014 Jan 31.

PMID:
24491909
2.

Targeted recombinant fusion proteins of IFNγ and mimetic IFNγ with PDGFβR bicyclic peptide inhibits liver fibrogenesis in vivo.

Bansal R, Prakash J, De Ruiter M, Poelstra K.

PLoS One. 2014 Feb 24;9(2):e89878. doi: 10.1371/journal.pone.0089878. eCollection 2014.

3.

Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis.

Bansal R, Prakash J, de Ruijter M, Beljaars L, Poelstra K.

Mol Pharm. 2011 Oct 3;8(5):1899-909. doi: 10.1021/mp200263q. Epub 2011 Aug 8.

PMID:
21800888
4.

Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor-beta on hepatic fibrosis in rats.

Li F, Li QH, Wang JY, Zhan CY, Xie C, Lu WY.

J Control Release. 2012 Apr 30;159(2):261-70. doi: 10.1016/j.jconrel.2011.12.023. Epub 2011 Dec 28.

PMID:
22226772
5.

Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice.

Bansal R, Prakash J, Post E, Beljaars L, Schuppan D, Poelstra K.

Hepatology. 2011 Aug;54(2):586-96. doi: 10.1002/hep.24395. Epub 2011 Jun 26.

PMID:
21538439
6.

3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression.

Zhang Z, Gao Z, Hu W, Yin S, Wang C, Zang Y, Chen J, Zhang J, Dong L.

Br J Pharmacol. 2013 Oct;170(3):649-60. doi: 10.1111/bph.12323.

7.

Caffeine prevents experimental liver fibrosis by blocking the expression of TGF-β.

Arauz J, Zarco N, Segovia J, Shibayama M, Tsutsumi V, Muriel P.

Eur J Gastroenterol Hepatol. 2014 Feb;26(2):164-73. doi: 10.1097/MEG.0b013e3283644e26.

PMID:
23903851
8.
9.

Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines.

Lu DH, Guo XY, Qin SY, Luo W, Huang XL, Chen M, Wang JX, Ma SJ, Yang XW, Jiang HX.

World J Gastroenterol. 2015 Feb 7;21(5):1531-45. doi: 10.3748/wjg.v21.i5.1531.

10.

K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells.

Freise C, Heldwein S, Erben U, Hoyer J, Köhler R, Jöhrens K, Patsenker E, Ruehl M, Seehofer D, Stickel F, Somasundaram R.

Liver Int. 2015 Apr;35(4):1244-52. doi: 10.1111/liv.12681. Epub 2014 Sep 22.

PMID:
25212242
11.

Ameliorative effect of grape seed proanthocyanidin extract on thioacetamide-induced mouse hepatic fibrosis.

Li J, Li J, Li S, He B, Mi Y, Cao H, Zhang C, Li L.

Toxicol Lett. 2012 Sep 18;213(3):353-60. doi: 10.1016/j.toxlet.2012.07.019. Epub 2012 Jul 31.

PMID:
22863721
13.

NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats.

Lin N, Chen S, Pan W, Xu L, Hu K, Xu R.

Am J Physiol Cell Physiol. 2011 Aug;301(2):C469-77. doi: 10.1152/ajpcell.00452.2010. Epub 2011 May 4.

14.

Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice.

Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y, Scholten D, Cong M, Iwaisako K, Liu X, Zhang M, Osterreicher CH, Stickel F, Ley K, Brenner DA, Kisseleva T.

Gastroenterology. 2012 Sep;143(3):765-76.e1-3. doi: 10.1053/j.gastro.2012.05.049. Epub 2012 Jun 8.

15.

Icaritin induces cell death in activated hepatic stellate cells through mitochondrial activated apoptosis and ameliorates the development of liver fibrosis in rats.

Li J, Liu P, Zhang R, Cao L, Qian H, Liao J, Xu W, Wu M, Yin Z.

J Ethnopharmacol. 2011 Sep 1;137(1):714-23. doi: 10.1016/j.jep.2011.06.030. Epub 2011 Jun 24.

PMID:
21726622
16.

Upregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: role of NADPH oxidase.

Wang M, Abais JM, Meng N, Zhang Y, Ritter JK, Li PL, Tang WX.

Free Radic Biol Med. 2014 Jun;71:109-20. doi: 10.1016/j.freeradbiomed.2014.03.015. Epub 2014 Mar 19.

PMID:
24657416
17.

Fibromodulin, an oxidative stress-sensitive proteoglycan, regulates the fibrogenic response to liver injury in mice.

Mormone E, Lu Y, Ge X, Fiel MI, Nieto N.

Gastroenterology. 2012 Mar;142(3):612-621.e5. doi: 10.1053/j.gastro.2011.11.029. Epub 2011 Dec 1.

18.

Morin ameliorates chemically induced liver fibrosis in vivo and inhibits stellate cell proliferation in vitro by suppressing Wnt/β-catenin signaling.

MadanKumar P, NaveenKumar P, Manikandan S, Devaraj H, NiranjaliDevaraj S.

Toxicol Appl Pharmacol. 2014 Jun 1;277(2):210-20. doi: 10.1016/j.taap.2014.03.008. Epub 2014 Mar 20.

PMID:
24657339
19.

Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis.

Baroni GS, D'Ambrosio L, Curto P, Casini A, Mancini R, Jezequel AM, Benedetti A.

Hepatology. 1996 May;23(5):1189-99.

PMID:
8621153
20.

Anti-fibrotic effect of thymoquinone on hepatic stellate cells.

Ghazwani M, Zhang Y, Gao X, Fan J, Li J, Li S.

Phytomedicine. 2014 Feb 15;21(3):254-60. doi: 10.1016/j.phymed.2013.09.014. Epub 2013 Oct 30.

PMID:
24182989
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