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Results: 1 to 20 of 118

1.

Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation.

Kim S, Lee HG, Park SA, Kundu JK, Keum YS, Cha YN, Na HK, Surh YJ.

PLoS One. 2014 Jan 28;9(1):e85984. doi: 10.1371/journal.pone.0085984. eCollection 2014.

PMID:
24489685
[PubMed - in process]
Free PMC Article
2.

Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes.

Tsai CY, Wang CC, Lai TY, Tsu HN, Wang CH, Liang HY, Kuo WW.

Int J Cardiol. 2013 Sep 30;168(2):1286-97. doi: 10.1016/j.ijcard.2012.12.004. Epub 2013 Feb 27.

PMID:
23453443
[PubMed - indexed for MEDLINE]
3.

Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.

Chen C, Pung D, Leong V, Hebbar V, Shen G, Nair S, Li W, Kong AN.

Free Radic Biol Med. 2004 Nov 15;37(10):1578-90.

PMID:
15477009
[PubMed - indexed for MEDLINE]
4.

Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.

Fisher CD, Augustine LM, Maher JM, Nelson DM, Slitt AL, Klaassen CD, Lehman-McKeeman LD, Cherrington NJ.

Drug Metab Dispos. 2007 Jun;35(6):995-1000. Epub 2007 Mar 12.

PMID:
17353348
[PubMed - indexed for MEDLINE]
Free Article
5.

Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.

Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.

Arch Biochem Biophys. 2010 Sep 1;501(1):142-50. doi: 10.1016/j.abb.2010.06.011. Epub 2010 Jun 15.

PMID:
20558128
[PubMed - indexed for MEDLINE]
6.

Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.

Surh YJ, Kundu JK, Na HK.

Planta Med. 2008 Oct;74(13):1526-39. doi: 10.1055/s-0028-1088302. Epub 2008 Oct 20. Review.

PMID:
18937164
[PubMed - indexed for MEDLINE]
7.

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways.

Gan FF, Ling H, Ang X, Reddy SA, Lee SS, Yang H, Tan SH, Hayes JD, Chui WK, Chew EH.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):852-62. doi: 10.1016/j.taap.2013.07.011. Epub 2013 Jul 27.

PMID:
23899529
[PubMed - indexed for MEDLINE]
8.

Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.

Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T.

J Pharmacol Exp Ther. 2009 Oct;331(1):255-64. doi: 10.1124/jpet.109.152702. Epub 2009 Jul 23.

PMID:
19628634
[PubMed - indexed for MEDLINE]
Free Article
9.

CO/HO-1 Induces NQO-1 Expression via Nrf2 Activation.

Kim HJ, Zheng M, Kim SK, Cho JJ, Shin CH, Joe Y, Chung HT.

Immune Netw. 2011 Dec;11(6):376-82. doi: 10.4110/in.2011.11.6.376. Epub 2011 Dec 31.

PMID:
22346778
[PubMed]
Free PMC Article
10.

Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.

He X, Ma Q.

J Pharmacol Exp Ther. 2010 Jan;332(1):66-75. doi: 10.1124/jpet.109.160465. Epub 2009 Oct 6.

PMID:
19808700
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Induction of NAD(P)H:quinone oxidoreductase 1 expression by cysteine via Nrf2 activation in human intestinal epithelial LS180 cells.

Satsu H, Chidachi E, Hiura Y, Ogiwara H, Gondo Y, Shimizu M.

Amino Acids. 2012 Oct;43(4):1547-555.

PMID:
22302369
[PubMed - indexed for MEDLINE]
12.

Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1.

Na HK, Kim EH, Choi MA, Park JM, Kim DH, Surh YJ.

Biochem Pharmacol. 2012 Nov 15;84(10):1241-50. doi: 10.1016/j.bcp.2012.08.024. Epub 2012 Sep 6.

PMID:
22981381
[PubMed - indexed for MEDLINE]
13.

Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway.

Wu J, Liu X, Fan J, Chen W, Wang J, Zeng Y, Feng X, Yu X, Yang X.

Toxicology. 2014 Apr 6;318:22-31. doi: 10.1016/j.tox.2014.01.008. Epub 2014 Feb 12.

PMID:
24530882
[PubMed - indexed for MEDLINE]
14.

Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes.

Keum YS, Han YH, Liew C, Kim JH, Xu C, Yuan X, Shakarjian MP, Chong S, Kong AN.

Pharm Res. 2006 Nov;23(11):2586-94. Epub 2006 Oct 18.

PMID:
17048120
[PubMed - indexed for MEDLINE]
16.

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.

Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):27-36. doi: 10.1016/j.taap.2009.12.012. Epub 2009 Dec 21.

PMID:
20026152
[PubMed - indexed for MEDLINE]
17.

Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediated NQO1 expression.

Korenori Y, Tanigawa S, Kumamoto T, Qin S, Daikoku Y, Miyamori K, Nagai M, Hou DX.

Mol Nutr Food Res. 2013 May;57(5):854-64. doi: 10.1002/mnfr.201200689. Epub 2013 Feb 6.

PMID:
23390006
[PubMed - indexed for MEDLINE]
18.

Regulation of genes encoding NAD(P)H:quinone oxidoreductases.

Jaiswal AK.

Free Radic Biol Med. 2000 Aug;29(3-4):254-62. Review.

PMID:
11035254
[PubMed - indexed for MEDLINE]
19.

The Helicobacter pylori protein HspB interferes with Nrf2/Keap1 pathway altering the antioxidant response of Ags cells.

Buommino E, Donnarumma G, Manente L, De Filippis A, Silvestri F, Iaquinto S, Tufano MA, De Luca A.

Helicobacter. 2012 Dec;17(6):417-25. doi: 10.1111/j.1523-5378.2012.00973.x. Epub 2012 Jul 11.

PMID:
23066931
[PubMed - indexed for MEDLINE]
20.

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells.

Li CQ, Kim MY, Godoy LC, Thiantanawat A, Trudel LJ, Wogan GN.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14547-51. doi: 10.1073/pnas.0907539106. Epub 2009 Aug 11.

PMID:
19706542
[PubMed - indexed for MEDLINE]
Free PMC Article

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