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Results: 1 to 20 of 87

1.

Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration.

Bernis C, Swift-Taylor B, Nord M, Carmona S, Chook YM, Forbes DJ.

Mol Biol Cell. 2014 Apr;25(7):992-1009. doi: 10.1091/mbc.E13-08-0506. Epub 2014 Jan 29.

PMID:
24478460
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly.

Lau CK, Delmar VA, Chan RC, Phung Q, Bernis C, Fichtman B, Rasala BA, Forbes DJ.

Mol Biol Cell. 2009 Sep;20(18):4043-58. doi: 10.1091/mbc.E09-02-0152. Epub 2009 Jul 29.

PMID:
19641022
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Analysis of a RanGTP-regulated gradient in mitotic somatic cells.

Kaláb P, Pralle A, Isacoff EY, Heald R, Weis K.

Nature. 2006 Mar 30;440(7084):697-701.

PMID:
16572176
[PubMed - indexed for MEDLINE]
4.

The translocation of transportin-cargo complexes through nuclear pores is independent of both Ran and energy.

Ribbeck K, Kutay U, Paraskeva E, Görlich D.

Curr Biol. 1999 Jan 14;9(1):47-50.

PMID:
9889126
[PubMed - indexed for MEDLINE]
Free Article
5.

Importazole, a small molecule inhibitor of the transport receptor importin-β.

Soderholm JF, Bird SL, Kalab P, Sampathkumar Y, Hasegawa K, Uehara-Bingen M, Weis K, Heald R.

ACS Chem Biol. 2011 Jul 15;6(7):700-8. doi: 10.1021/cb2000296. Epub 2011 Apr 21.

PMID:
21469738
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitors.

Shah S, Forbes DJ.

Curr Biol. 1998 Dec 17-31;8(25):1376-86.

PMID:
9889100
[PubMed - indexed for MEDLINE]
Free Article
7.

Importin beta is a mitotic target of the small GTPase Ran in spindle assembly.

Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K.

Cell. 2001 Jan 12;104(1):95-106.

PMID:
11163243
[PubMed - indexed for MEDLINE]
Free Article
8.

The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation.

Yokoyama H, Koch B, Walczak R, Ciray-Duygu F, González-Sánchez JC, Devos DP, Mattaj IW, Gruss OJ.

Nat Commun. 2014;5:3270. doi: 10.1038/ncomms4270.

PMID:
24509916
[PubMed - in process]
9.

HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes.

Silljé HH, Nagel S, Körner R, Nigg EA.

Curr Biol. 2006 Apr 18;16(8):731-42.

PMID:
16631580
[PubMed - indexed for MEDLINE]
Free Article
10.

The RanGTP gradient - a GPS for the mitotic spindle.

Kalab P, Heald R.

J Cell Sci. 2008 May 15;121(Pt 10):1577-86. doi: 10.1242/jcs.005959.

PMID:
18469014
[PubMed - indexed for MEDLINE]
Free Article
11.

Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly.

Harel A, Chan RC, Lachish-Zalait A, Zimmerman E, Elbaum M, Forbes DJ.

Mol Biol Cell. 2003 Nov;14(11):4387-96. Epub 2003 Aug 7.

PMID:
14551248
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus.

Izaurralde E, Kutay U, von Kobbe C, Mattaj IW, Görlich D.

EMBO J. 1997 Nov 3;16(21):6535-47.

PMID:
9351834
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr.

Shah S, Tugendreich S, Forbes D.

J Cell Biol. 1998 Apr 6;141(1):31-49.

PMID:
9531546
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Importin beta regulates the seeding of chromatin with initiation sites for nuclear pore assembly.

Rotem A, Gruber R, Shorer H, Shaulov L, Klein E, Harel A.

Mol Biol Cell. 2009 Sep;20(18):4031-42. doi: 10.1091/mbc.E09-02-0150. Epub 2009 Jul 22.

PMID:
19625448
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Definition of a consensus transportin-specific nucleocytoplasmic transport signal.

Bogerd HP, Benson RE, Truant R, Herold A, Phingbodhipakkiya M, Cullen BR.

J Biol Chem. 1999 Apr 2;274(14):9771-7.

PMID:
10092666
[PubMed - indexed for MEDLINE]
Free Article
16.

Transportin is a major nuclear import receptor for c-Fos: a novel mode of cargo interaction.

Arnold M, Nath A, Wohlwend D, Kehlenbach RH.

J Biol Chem. 2006 Mar 3;281(9):5492-9. Epub 2006 Jan 2.

PMID:
16407315
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of importin-beta in coupling Ran to downstream targets in microtubule assembly.

Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y.

Science. 2001 Jan 26;291(5504):653-6.

PMID:
11229403
[PubMed - indexed for MEDLINE]
Free Article
18.

New mitotic regulators released from chromatin.

Yokoyama H, Gruss OJ.

Front Oncol. 2013 Dec 16;3:308. doi: 10.3389/fonc.2013.00308. Review.

PMID:
24380075
[PubMed]
Free PMC Article
19.

Spatial and temporal control of nuclear envelope assembly by Ran GTPase.

Clarke PR, Zhang C.

Symp Soc Exp Biol. 2004;(56):193-204. Review.

PMID:
15565882
[PubMed - indexed for MEDLINE]
20.

Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells.

Ciciarello M, Mangiacasale R, Thibier C, Guarguaglini G, Marchetti E, Di Fiore B, Lavia P.

J Cell Sci. 2004 Dec 15;117(Pt 26):6511-22. Epub 2004 Nov 30.

PMID:
15572412
[PubMed - indexed for MEDLINE]
Free Article

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