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Items: 1 to 20 of 129


Claudin-3 and claudin-5 protein folding and assembly into the tight junction are controlled by non-conserved residues in the transmembrane 3 (TM3) and extracellular loop 2 (ECL2) segments.

Rossa J, Ploeger C, Vorreiter F, Saleh T, Protze J, Günzel D, Wolburg H, Krause G, Piontek J.

J Biol Chem. 2014 Mar 14;289(11):7641-53. doi: 10.1074/jbc.M113.531012. Epub 2014 Jan 29.


Molecular and structural transmembrane determinants critical for embedding claudin-5 into tight junctions reveal a distinct four-helix bundle arrangement.

Rossa J, Protze J, Kern C, Piontek A, Günzel D, Krause G, Piontek J.

Biochem J. 2014 Nov 15;464(1):49-60. doi: 10.1042/BJ20140431.


Probing the cis-arrangement of prototype tight junction proteins claudin-1 and claudin-3.

Milatz S, Piontek J, Schulzke JD, Blasig IE, Fromm M, Günzel D.

Biochem J. 2015 Jun 15;468(3):449-58. doi: 10.1042/BJ20150148. Epub 2015 Apr 7.


Freeze-fracture electron microscopic study of tight junction strands in HEK293 cells and MDCK II cells expressing claudin-1 mutants in the second extracellular loop.

Inai T, Sengoku A, Hirose E, Iida H, Shibata Y.

Histochem Cell Biol. 2009 Jun;131(6):681-90. doi: 10.1007/s00418-009-0571-7. Epub 2009 Feb 21.


Mechanism of Clostridium perfringens enterotoxin interaction with claudin-3/-4 protein suggests structural modifications of the toxin to target specific claudins.

Veshnyakova A, Piontek J, Protze J, Waziri N, Heise I, Krause G.

J Biol Chem. 2012 Jan 13;287(3):1698-708. doi: 10.1074/jbc.M111.312165. Epub 2011 Nov 28.


Manner of interaction of heterogeneous claudin species within and between tight junction strands.

Furuse M, Sasaki H, Tsukita S.

J Cell Biol. 1999 Nov 15;147(4):891-903.


Formation of tight junction: determinants of homophilic interaction between classic claudins.

Piontek J, Winkler L, Wolburg H, Müller SL, Zuleger N, Piehl C, Wiesner B, Krause G, Blasig IE.

FASEB J. 2008 Jan;22(1):146-58. Epub 2007 Aug 29.


Model for the architecture of claudin-based paracellular ion channels through tight junctions.

Suzuki H, Tani K, Tamura A, Tsukita S, Fujiyoshi Y.

J Mol Biol. 2015 Jan 30;427(2):291-7. doi: 10.1016/j.jmb.2014.10.020. Epub 2014 Nov 4.


Claudin-7 expressed on lateral membrane of rat epididymal epithelium does not form aberrant tight junction strands.

Inai T, Sengoku A, Hirose E, Iida H, Shibata Y.

Anat Rec (Hoboken). 2007 Nov;290(11):1431-8.


Elucidating the principles of the molecular organization of heteropolymeric tight junction strands.

Piontek J, Fritzsche S, Cording J, Richter S, Hartwig J, Walter M, Yu D, Turner JR, Gehring C, Rahn HP, Wolburg H, Blasig IE.

Cell Mol Life Sci. 2011 Dec;68(23):3903-18. doi: 10.1007/s00018-011-0680-z. Epub 2011 May 1.


Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5.

Protze J, Eichner M, Piontek A, Dinter S, Rossa J, Blecharz KG, Vajkoczy P, Piontek J, Krause G.

Cell Mol Life Sci. 2015 Apr;72(7):1417-32. doi: 10.1007/s00018-014-1761-6. Epub 2014 Oct 24.


Overexpression of claudin-5 but not claudin-3 induces formation of trans-interaction-dependent multilamellar bodies.

Rossa J, Lorenz D, Ringling M, Veshnyakova A, Piontek J.

Ann N Y Acad Sci. 2012 Jun;1257:59-66. doi: 10.1111/j.1749-6632.2012.06546.x.


Structure and function of extracellular claudin domains.

Krause G, Winkler L, Piehl C, Blasig I, Piontek J, Müller SL.

Ann N Y Acad Sci. 2009 May;1165:34-43. doi: 10.1111/j.1749-6632.2009.04057.x.


The protoplasmic or exoplasmic face association of tight junction particles cannot predict paracellular permeability or heterotypic claudin compatibility.

Inai T, Kamimura T, Hirose E, Iida H, Shibata Y.

Eur J Cell Biol. 2010 Jul;89(7):547-56. doi: 10.1016/j.ejcb.2010.01.003. Epub 2010 Feb 25.


In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization.

Cording J, Berg J, Käding N, Bellmann C, Tscheik C, Westphal JK, Milatz S, Günzel D, Wolburg H, Piontek J, Huber O, Blasig IE.

J Cell Sci. 2013 Jan 15;126(Pt 2):554-64. doi: 10.1242/jcs.114306. Epub 2012 Nov 30.


Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells.

McCarthy KM, Francis SA, McCormack JM, Lai J, Rogers RA, Skare IB, Lynch RD, Schneeberger EE.

J Cell Sci. 2000 Oct;113 Pt 19:3387-98.


Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens.

Yamazaki Y, Tokumasu R, Kimura H, Tsukita S.

Mol Biol Cell. 2011 May;22(9):1495-504. doi: 10.1091/mbc.E10-12-1003. Epub 2011 Mar 3.

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